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pro vyhledávání: '"physiology [Fragile X Mental Retardation Protein]"'
Autor:
Phillip A. Sharp, Bridget M. Dolan, Kelly A. Foster, Dieter Edbauer, Chi-Fong Wang, Tomoko Tada, Morgan Sheng, Joel R. Neilson, Matthew N. Batterton, Daniel P. Seeburg
Publikováno v:
Neuron 65(3), 373-384 (2010). doi:10.1016/j.neuron.2010.01.005
SummaryMicroRNAs (miRNAs) are noncoding RNAs that suppress translation of specific mRNAs. The miRNA machinery interacts with fragile X mental retardation protein (FMRP), which functions as translational repressor. We show that miR-125b and miR-132, a