Výsledky vyhledávání - "physiology [Embryonic Stem Cells]"

Developmental HCN channelopathy results in decreased neural progenitor proliferation and microcephaly in mice

Autor: Jochen Roeper, Niklas Kleinenkuhnen, Malte Stockebrand, Marta Florio, Anna Katharina Schlusche, Igor Jakovcevski, Sabine Ulrike Vay, Steffi Sandke, Dirk Isbrandt, Achim Tresch, Wieland B. Huttner, Rafael Campos-Martin, Maria Adele Rueger

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America 118(35), e2009393118 (2021). doi:10.1073/pnas.2009393118
Proc Natl Acad Sci U S A

The development of the cerebral cortex relies on the controlled division of neural stem and progenitor cells. The requirement for precise spatiotemporal control of proliferation and cell fate places a high demand on the cell division machinery, and d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a71eaa9257832f436b89f3211d3ea06
https://pub.dzne.de/record/162815

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Pluripotent stem cell-derived radial glia-like cells as stable intermediate for efficient generation of human oligodendrocytes

Autor: Gorris, Raphaela, Fischer, Julia, Brüstle, Oliver, Erwes, Kim Lina, Kesavan, Jaideep, Peterson, Daniel A, Alexander, Michael, Nöthen, Markus M, Peitz, Michael, Quandel, Tamara, Karus, Michael

Publikováno v: Glia 63(12), 2152-2167 (2015). doi:10.1002/glia.22882

Neural precursor cells (NPCs) derived from human pluripotent stem cells (hPSCs) represent an attractive tool for the in vitro generation of various neural cell types. However, the developmentally early NPCs emerging during hPSC differentiation typica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4dcaa6969dbd82e7367fc480320e9509
https://pubmed.ncbi.nlm.nih.gov/26123132

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Visualizing corticotropin-releasing hormone receptor type 1 expression and neuronal connectivities in the mouse using a novel multifunctional allele

Autor: Claudia Kühne, Wolfgang Wurst, Jan M. Deussing, Jochen Graw, Martin Hrabě de Angelis, Günther Schütz, Oliver Puk

Publikováno v: The journal of comparative neurology 520(14), 3150-3180 (2012). doi:10.1002/cne.23082

The corticotropin-releasing hormone (CRH) and its type 1 receptor (CRHR1) play a central role in coordinating the endocrine, autonomic, and behavioral responses to stress. A prerequisite to functionally dissect the complexity of the CRH/CRHR1 system

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e019eac943d77a8470d9746a0e157190
https://pubmed.ncbi.nlm.nih.gov/22886732

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miR-7 and miR-214 are specifically expressed during neuroblastoma differentiation, cortical development and embryonic stem cells differentiation, and control neurite outgrowth in vitro

Autor: Paola Tucci, Hailan Chen, Mariuca Vasa-Nicotera, Daniel Aberdam, Shu-Dong Zhang, Joan Riley, Massimiliano Agostini, Pierluigi Nicotera, Ruby Shalom-Feuerstein, Gerry Melino, Giuseppe Genchi, Richard A. Knight

Publikováno v: Biochemical and biophysical research communications 394(4), 921-927 (2010). doi:10.1016/j.bbrc.2010.03.076

The mammalian nervous system exerts essential control on many physiological processes in the organism and is itself controlled extensively by a variety of genetic regulatory mechanisms. microRNA (miR), an abundant class of small non-coding RNA, are e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5fe01c7261765dfd3086e41d1b968fd
https://pubmed.ncbi.nlm.nih.gov/20230785

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Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP

Autor: Luca Giovanni Di Giovannantonio, Antonio Simeone, Wolfgang Wurst, Raffaele Prosperi, Dario Acampora, Daniela Omodei, Michela Di Salvio, Nilima Prakash

Publikováno v: Nature neuroscience
13 (2010): 1481–1488. doi:10.1038/nn.2661
info:cnr-pdr/source/autori:Di Salvio M.; Di Giovannantonio L.G.; Acampora D.; Prosperi R.; Omodei D.; Prakash N.; Wurst W.; Simeone A./titolo:Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP/doi:10.1038%2Fnn.2661/rivista:Nature neuroscience (Print)/anno:2010/pagina_da:1481/pagina_a:1488/intervallo_pagine:1481–1488/volume:13
Nature reviews / Neuroscience 13(12), 1481-1488 (2010). doi:10.1038/nn.2661
Nature Neuroscience; Vol 13

Mesencephalic-diencephalic dopaminergic neurons control locomotor activity and emotion and are affected in neurodegenerative and psychiatric diseases. The homeoprotein Otx2 is restricted to ventral tegmental area (VTA) neurons that are prevalently co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06928c2ccaedce1ec00354e5a4fe1e79
https://publications.cnr.it/doc/27006

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