Zobrazeno 1 - 10 of 17 pro vyhledávání: '"physiology [Dopamine]"'
1
Adaptive changes in striatal projection neurons explain the long duration response and the emergence of dyskinesias in patients with Parkinson's disease
Autor: Björn Falkenburger, Theodoros Kalliakoudas, Heinz Reichmann
Publikováno v: Journal of neural transmission 129, 497-503 (2022). doi:10.1007/s00702-022-02510-8
Neuronal activity in the brain is tightly regulated. During operation in real time, for instance, feedback and feedforward loops limit excessive excitation. In addition, cell autonomous processes ensure that neurons’ average activity is restored to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b99b0289b8be5e128d065675ccf69c8c
https://pubmed.ncbi.nlm.nih.gov/35538324
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2
Frequency-dependent electrical stimulation of fimbria-fornix preferentially affects the mesolimbic dopamine system or prefrontal cortex
Autor: Cornelia Helbing, Frank Angenstein
Publikováno v: Brain stimulation, 13(3):753-764
Brain Stimulation, Vol 13, Iss 3, Pp 753-764 (2020)
Brain stimulation 13(3), 753-764 (2020). doi:10.1016/j.brs.2020.02.026
Background The fimbria/fornix fiber system is an essential part of the hippocampal-VTA loop, and therefore activities that are propagated through this fiber system control the activity of the mesolimbic dopamine system. Objectives/hypothesis We hypot
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fee0da0c1f06cac05a1f6ff8c4f1f723
https://repository.publisso.de/resource/frl:6420609
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3
Do TRPC channels support working memory? Comparing modulations of TRPC channels and working memory through G-protein coupled receptors and neuromodulators
Autor: Frederik M. Theissen, Maria J. Valero-Aracama, Mihaela A. Corbu, Antonio Reboreda, Alberto Arboit, Motoharu Yoshida
Publikováno v: Behavioural brain research 354, 64-83 (2018). doi:10.1016/j.bbr.2018.02.042
Working memory is a crucial ability we use in daily life. However, the cellular mechanisms supporting working memory still remain largely unclear. A key component of working memory is persistent neural firing which is believed to serve short-term (hu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99acba382341226493ae3a98da9ce308
https://pubmed.ncbi.nlm.nih.gov/29501506
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4
Action versus valence in decision making
Autor: Marc, Guitart-Masip, Emrah, Duzel, Ray, Dolan, Peter, Dayan
Publikováno v: Trends in Cognitive Sciences
Trends in cognitive sciences 18(4), 194-202 (2014). doi:10.1016/j.tics.2014.01.003
Highlights • Pavlovian responses couple action and valence. • This coupling interferes with instrumental learning and performance. • Action dominates valence in the striatum and dopaminergic midbrain. • Boosting dopamine enhances the dominanc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fec54b11d3e89827cde9e52efd25d301
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5
Dopamine Modulates Episodic Memory Persistence in Old Age
Autor: Raymond J. Dolan, Marc Guitart-Masip, Emrah Düzel, Nico Bunzeck, Rumana Chowdhury
Publikováno v: The Journal of Neuroscience
The journal of neuroscience 32(41), 14193-14204 (2012). doi:10.1523/JNEUROSCI.1278-12.2012
Activation of the hippocampus is required to encode memories for new events (or episodes). Observations from animal studies suggest that, for these memories to persist beyond 4–6 h, a release of dopamine generated by strong hippocampal activation i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17650710618335b2a6f25361db552508
https://doi.org/10.1523/jneurosci.1278-12.2012
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6
Predictive value and reward in implicit classification learning
Autor: Hans-Otto Karnath, Judith M. Lam, Tobias Wächter, Andreas R. Luft, Christoph Globas
Publikováno v: Hum Brain Mapp
Human brain mapping 34(1), 176-185 (2012). doi:10.1002/hbm.21431
Learning efficacy depends on its emotional context. The contents learned and the feedback received during training tinges this context. The objective here was to investigate the influence of content and feedback on the efficacy of implicit learning a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b37e00bc912cb48576b89ae324a073
https://doi.org/10.1002/hbm.21431
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7
Pitx3 Is a Critical Mediator of GDNF-Induced BDNF Expression in Nigrostriatal Dopaminergic Neurons
Autor: Meng Li, Rüdiger Klein, Changgeng Peng, Wolfgang Wurst, Nilima Prakash, Liviu Aron, Weidong Le
Publikováno v: J. Neurosci. 31, 12802-12815 (2011)
The journal of neuroscience 31(36), 12802-12815 (2011). doi:10.1523/JNEUROSCI.0898-11.2011
Journal of Neuroscience
Pitx3 is a critical homeodomain transcription factor for the proper development and survival of mesodiencephalic dopaminergic (mdDA) neurons in mammals. Several variants of this gene have been associated with human Parkinson's disease (PD), and lack
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::545f96db56ede28fba08ba1fcb6293d2
https://doi.org/10.1523/jneurosci.0898-11.2011
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8
Effects of transcranial direct current stimulation (tDCS) on executive functions: influence of COMT Val/Met polymorphism
Autor: Bastian Zwissler, Rejko Krüger, Brigitte Maurer, Katrin Elisabeth Giel, Christian Plewnia, Isabella Längst
Publikováno v: Cortex 49(7), 1801-1807 (2013). doi:10.1016/j.cortex.2012.11.002
Introduction Transcranial direct current stimulation (tDCS) is a frequently used technique to investigate healthy and impaired neuronal functions. Its modulatory effect on executive functions is of particular interest for understanding the mechanisms
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97deb435193f683916b08a1642945697
https://pubmed.ncbi.nlm.nih.gov/23237479
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9
Dopamine modulates memory consolidation of discrimination learning in the auditory cortex
Autor: Schicknick, Horst, Reichenbach, Nicole, Smalla, Karl-Heinz, Scheich, Henning, Gundelfinger, Eckart D, Tischmeyer, Wolfgang
Publikováno v: European journal of neuroscience 35(5), 763-774 (2012). doi:10.1111/j.1460-9568.2012.07994.x
In Mongolian gerbils, the auditory cortex is critical for discriminating rising vs. falling frequency-modulated tones. Based on our previous studies, we hypothesized that dopaminergic inputs to the auditory cortex during and shortly after acquisition
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::61268c42000ea66c013bcda019aab0aa
https://pubmed.ncbi.nlm.nih.gov/22339853
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10
An imperfect dopaminergic error signal can drive temporal-difference learning
Autor: Wiebke Potjans, Markus Diesmann, Abigail Morrison
Publikováno v: PLoS Computational Biology, Vol 7, Iss 5, p e1001133 (2011)
PLoS computational biology 7(5), e1001133 (2011). doi:10.1371/journal.pcbi.1001133
PLoS Computational Biology
PLoS Computational Biology 7, e1001133 (2011). doi:10.1371/journal.pcbi.1001133
An open problem in the field of computational neuroscience is how to link synaptic plasticity to system-level learning. A promising framework in this context is temporal-difference (TD) learning. Experimental evidence that supports the hypothesis tha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd1528907840a6f6b21897e8ffd095cd
http://europepmc.org/articles/PMC3093351?pdf=render
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