Zobrazeno 1 - 10
of 14
pro vyhledávání: '"physiology [Dendritic Spines]"'
Autor:
Nebeling, Felix Christopher, Poll, Stefanie, Justus, Lena Christine, Steffen, Julia, Keppler, Kevin, Mittag, Manuel, Fuhrmann, Martin
Publikováno v:
eLife 12, e83176 (2023). doi:10.7554/eLife.83176
Microglia, the resident immune cells of the brain, play a complex role in health and disease. They actively survey the brain parenchyma by physically interacting with other cells and structurally shaping the brain. Yet, the mechanisms underlying micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ae378542f1328423466e5a760e08623
https://doi.org/10.7554/elife.83176
https://doi.org/10.7554/elife.83176
Autor:
Fabio Bertan, Lena Wischhof, Liudmila Sosulina, Manuel Mittag, Dennis Dalügge, Alessandra Fornarelli, Fabrizio Gardoni, Elena Marcello, Monica Di Luca, Martin Fuhrmann, Stefan Remy, Daniele Bano, Pierluigi Nicotera
Publikováno v:
Cell Death & Differentiation
Cell death and differentiation, 27(12):3354-3373
Cell Death and Differentiation
Cell death and differentiation 27(12), 3354-3373 (2020). doi:10.1038/s41418-020-0584-2
Cell death and differentiation, 27(12):3354-3373
Cell Death and Differentiation
Cell death and differentiation 27(12), 3354-3373 (2020). doi:10.1038/s41418-020-0584-2
Dendritic spines are postsynaptic domains that shape structural and functional properties of neurons. Upon neuronal activity, Ca2+ transients trigger signaling cascades that determine the plastic remodeling of dendritic spines, which modulate learnin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0277fd5150bdb3eaabea65eab22dcf
https://doi.org/10.1038/s41418-020-0584-2
https://doi.org/10.1038/s41418-020-0584-2
Autor:
Nicholas Cole, Katrin Böhm, Lucie Bard, Monika Bijata, Schwab Mh, Bijata K, Compan, Andre Zeug, Cherkas, Jakub Wlodarczyk, Yvonne Schill, Abdel-Galil D, Dmitri A. Rusakov, Subhadip Basu, Olga Kopach, Evgeni Ponimaskin, Alexander Dityatev, Michiyuki Matsuda
Publikováno v:
Communications biology 3(1), 76 (2020). doi:10.1038/s42003-020-0791-x
Communications Biology, Vol 3, Iss 1, Pp 1-16 (2020)
Communications Biology, Vol 3, Iss 1, Pp 1-16 (2020)
Activity-dependent remodeling of excitatory connections underpins memory formation in the brain. Serotonin receptors are known to contribute to such remodeling, yet the underlying molecular machinery remains poorly understood. Here, we employ high-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbaaa183eeb5c3d111d335105bf6594d
https://pub.dzne.de/record/151632
https://pub.dzne.de/record/151632
Autor:
Juha Saarikangas, Geneviève Chazal, Lore Becker, Valerie Gailus-Durner, Yosuke Senju, Rimante Minkeviciene, Thomas Klopstock, Martin Hrabě de Angelis, Lotta von Ossowski, Tomi Taira, Helmut Fuchs, Wolfgang Hans, Lillian Garrett, Sabine M. Hölter, Andreas Zimmer, Nazim Kourdougli, Pirta Hotulainen, Claudio Rivera, Ildiko Racz, Jaakko Kuurne, Pieta K. Mattila, Wolfgang Wurst, Mikael Segerstråle, Pekka Lappalainen
Publikováno v:
Dev. Cell 33, 644-659 (2015)
Developmental cell 33(6), 644-659 (2015). doi:10.1016/j.devcel.2015.04.014
Developmental cell 33(6), 644-659 (2015). doi:10.1016/j.devcel.2015.04.014
SummaryProper morphogenesis of neuronal dendritic spines is essential for the formation of functional synaptic networks. However, it is not known how spines are initiated. Here, we identify the inverse-BAR (I-BAR) protein MIM/MTSS1 as a nucleator of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68204dd715fc46291e65a034be0a265b
Publikováno v:
The journal of neuroscience 35(9), 3772-3781 (2015). doi:10.1523/JNEUROSCI.2043-14.2015
Classical conditioning that involves mnemonic processing, that is, a “trace” period between conditioned and unconditioned stimulus, requires awareness of the association to be formed and is considered a simple model paradigm for declarative learn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf2f2f59e8cdc9d83a7a2d45aa73161d
https://doi.org/10.1523/jneurosci.2043-14.2015
https://doi.org/10.1523/jneurosci.2043-14.2015
Autor:
Pfeiffer, Thomas, Poll, Stefanie, Bancelin, Stephane, Angibaud, Julie, Inavalli, VVG Krishna, Keppler, Kevin, Mittag, Manuel, Fuhrmann, Martin, Nägerl, U Valentin
Publikováno v:
eLife 7, e34700 (2018). doi:10.7554/eLife.34700
eLife, Vol 7 (2018)
eLife
eLife, Vol 7 (2018)
eLife
Rewiring neural circuits by the formation and elimination of synapses is thought to be a key cellular mechanism of learning and memory in the mammalian brain. Dendritic spines are the postsynaptic structural component of excitatory synapses, and thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::89a655a23b1222635061fa14c41635c4
Autor:
Miriam Chamoun, Jens Wagner, Felix Nebeling, Stefanie Kleiber, Lena C. Schmid, Martin Fuhrmann, Ligang Gu, Julia Steffen
Publikováno v:
The journal of neuroscience 34(42), 13948-13953 (2014). doi:10.1523/JNEUROSCI.1464-14.2014
Hippocampal function is important for learning and memory. During memory processing, hippocampal CA1 neurons play a crucial role by integrating excitatory synaptic input from CA3 and the entorhinal cortex. These neurons receive excitatory input almos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ebab8bd8dde6ea64cb5e89bdd5e599
https://doi.org/10.1523/jneurosci.1464-14.2014
https://doi.org/10.1523/jneurosci.1464-14.2014
Autor:
Anneke Kremer, Saak V. Ovsepian, Mario M. Dorostkar, G Aramuni, F. Van Leuven, Severin Filser, Christian Schön, Simon M. Ochs, Julia Pöschl, Jochen Herms
Publikováno v:
Europe PubMed Central
Molecular psychiatry 20(4), 482-489 (2014). doi:10.1038/mp.2014.55
Molecular Psychiatry
Molecular psychiatry 20(4), 482-489 (2014). doi:10.1038/mp.2014.55
Molecular Psychiatry
Central nervous glycogen synthase kinase 3β (GSK3β) is implicated in a number of neuropsychiatric diseases, such as bipolar disorder, depression, schizophrenia, fragile X syndrome or anxiety disorder. Many drugs employed to treat these conditions i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87263365e778bc6123c606053ba8c3c9
https://doi.org/10.1038/mp.2014.55
https://doi.org/10.1038/mp.2014.55
Autor:
Philippe Marin, Alexander Dityatev
Publikováno v:
Journal of neurochemistry 141(5), 644-646 (2017). doi:10.1111/jnc.13981
Read the highlighted article 'Serotonin 5-HT7 receptor increases the density of dendritic spines and facilitates synaptogenesis in forebrain neurons' on page 647.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0147e8b954689bdc6dc93f66bad9541d
https://pubmed.ncbi.nlm.nih.gov/28122114
https://pubmed.ncbi.nlm.nih.gov/28122114
Autor:
Eva Benito, Jeffrey McIlhinney, Hamid Ahmad, Saheeb Ahmed, Joaquin I. Hurtado-Zavala, Binu Ramachandran, Pavel V Perestenko, Katja Burk, Aarti Swaminathan, Camin Dean, Ankit Awasthi, Ruth Faram, Andre Fischer
Publikováno v:
Cerebral cortex 28(4), 1087-1104 (2017). doi:10.1093/cercor/bhx009
Dendritic spines compartmentalize information in the brain, and their morphological characteristics are thought to underly synaptic plasticity. Here we identify copine-6 as a novel modulator of dendritic spine morphology. We found that brain-derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c69651459715fc20ba48cd6dc51e4d13
https://pubmed.ncbi.nlm.nih.gov/28158493
https://pubmed.ncbi.nlm.nih.gov/28158493