Zobrazeno 1 - 10 of 11 pro vyhledávání: '"physiology [Carrier Proteins]"'
1
The Golgi-Associated PDZ Domain Protein Gopc/PIST Is Required for Synaptic Targeting of mGluR5
Autor: Alexander Dityatev, Inseon Song, Malte Klüssendorf, Fabio Morellini, Lynn Schau, Hans-Jürgen Kreienkamp, Judith Koliwer
Publikováno v: Molecular Neurobiology
Molecular neurobiology 58, 5618-5634 (2021). doi:10.1007/s12035-021-02504-9
In neuronal cells, many membrane receptors interact via their intracellular, C-terminal tails with PSD-95/discs large/ZO-1 (PDZ) domain proteins. Some PDZ proteins act as scaffold proteins. In addition, there are a few PDZ proteins such as Gopc which
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4efd6a224e5ae0af900c012afaa95cb6
http://europepmc.org/articles/PMC8599212
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2
Characterization of myo -Inositol Utilization by Corynebacterium glutamicum : the Stimulon, Identification of Transporters, and Influence on l -Lysine Formation
Autor: Volker F. Wendisch, Lothar Eggeling, Karin Krumbach, Eva Krings, Brigitte Bathe, Hermann Sahm, Ralf Kelle
Publikováno v: Journal of bacteriology 188(23), 8054-8061 (2006). doi:10.1128/JB.00935-06
Although numerous bacteria possess genes annotated iol in their genomes, there have been very few studies on the possibly associated myo -inositol metabolism and its significance for the cell. We found that Corynebacterium glutamicum utilizes myo -in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caaa1855edd3bb71f99611144a1ba41e
https://doi.org/10.1128/jb.00935-06
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3
Differential expression of the cationic amino acid transporter 2(B) in the adult rat brain
Autor: Claude Bachmann, Marc Loup, Masataka Mori, Tomomi Gotoh, Olivier Braissant
Publikováno v: Brain Research. Molecular Brain Research, vol. 91, no. 1-2, pp. 189-195
l -Arginine is a substrate for the synthesis of proteins, nitric oxide (NO), creatine, urea, proline, glutamate, polyamines and agmatine. In the central nervous system (CNS), arginine is extracted from the blood and exchanged by cells through carrier
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b61df736c5d8b3c83f851fb2c676ff04
https://doi.org/10.1016/s0169-328x(01)00113-9
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4
iRHOM2 takes control of rheumatoid arthritis
Autor: Stefan F. Lichtenthaler
Publikováno v: The journal of clinical investigation 123(2), JCI67548 (2013). doi:10.1172/JCI67548
iRHOM2, encoded by the gene Rhbdf2, regulates the maturation of the TNF-α convertase (TACE), which controls shedding of TNF-α and its biological activity in vivo. TACE is a potential target to treat TNF-α–dependent diseases, such as rheumatoid a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b422e1013d00f788786a23a2336e92a
https://pub.dzne.de/record/136783
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6
RIM-binding protein, a central part of the active zone, is essential for neurotransmitter release
Autor: Stephan J. Sigrist, Carolin Wichmann, Johanna Bückers, Elena Knoche, Dietmar Schmitz, Graeme W. Davis, Karen S. Y. Liu, Sara Mertel, Matthias Siebert, Stephanie Wegener, Tanja Matkovic, Harald Depner, Stefan W. Hell, Karzan Muhammad, Martin Müller, Christoph Mettke
Publikováno v: Science / Science now 334(6062), 1565-1569 (2011). doi:10.1126/science.1212991
Science (New York N.Y.)
Science
The molecular machinery mediating the fusion of synaptic vesicles (SVs) at presynaptic active zone (AZ) membranes has been studied in detail, and several essential components have been identified. AZ-associated protein scaffolds are viewed as only mo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df413e6e8928254013d484da4a2a902
https://pub.dzne.de/record/136382
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7
Niemann-Pick type C cells show cholesterol dependent decrease of APP expression at the cell surface and its increased processing through the beta-secretase pathway
Autor: Stefan Mitterreiter, Martina Malnar, Damir Omerbašić, Marko Kosicek, Silva Hećimović, Stefan F. Lichtenthaler, Alison Goate
Publikováno v: Biochimica et biophysica acta / Molecular basis of disease 1802(7-8), 682-691 (2010). doi:10.1016/j.bbadis.2010.05.006
Biochimica et Biophysica Acta-Molecular Basis of Disease
Biochimica et Biophysica Acta-Molecular Basis of Disease, Elsevier, 2010, 1802 (7-8), pp.682. ⟨10.1016/j.bbadis.2010.05.006⟩
Biochimica et biophysica acta : molecular basis of diseas
The link between cholesterol and Alzheimer's disease has recently been revealed in Niemann-Pick type C disease. We found that NPC1(-/-) cells show decreased expression of APP at the cell surface and increased processing of APP through the beta-secret
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2f6727d7dfbb240364d39e68b5ca47
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8
Bilirubin, a curse and a boon
Autor: J. D. Ostrow, Claudio Tiribelli
Unconjugated bilirubin is a curse at high concentrations, producing apoptosis and cell death, but a boon at more physiological levels, protecting cells against oxidant damage Both hydrophobic bile salts1,2 and unconjugated bilirubin (UCB)3 induce apo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c54421ba16936271c3b7414ef2907ba1
http://www.ncbi.nlm.nih.gov/pubmed/14633940
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9
Paradoxical [correction of parodoxical] effect of orexin A: hypophagia induced by hyperthermia
Autor: M, Monda, A, Viggiano, V, De Luca
This experiment tested the effect of the sympathetic and thermogenic activation induced by orexin A on eating behavior. The food intake, firing rate (FR) of the sympathetic nerves to interscapular brown adipose tissue (IBAT), IBAT and abdominal tempe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::684c914886da7fc4665707e9beee0b77
http://hdl.handle.net/11386/3930597
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10
Haloperidol reduces the sympathetic and thermogenic activation induced by orexin A
Autor: Marcellino Monda, Andrea Viggiano, V. De Luca
Publikováno v: Neuroscience research. 45(1)
This experiment tested the effect of haloperidol on the sympathetic and thermogenic effects induced by orexin A. The firing rates of the sympathetic nerves to interscapular brown adipose tissue (IBAT), along with IBAT and colonic temperatures and hea
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273ca66e1bb8ae48f6c82c143b76a9c2
https://pubmed.ncbi.nlm.nih.gov/12507720
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