Zobrazeno 1 - 10
of 13
pro vyhledávání: '"physiology [Astrocytes]"'
Autor:
Kiara Freitag, Pascale Eede, Andranik Ivanov, Nele Sterczyk, Shirin Schneeberger, Tatiana Borodina, Sascha Sauer, Dieter Beule, Frank L. Heppner
Publikováno v:
Communications biology 6(1), 40 (2023). doi:10.1038/s42003-023-04410-3
Astrocytes are resident glial cells of the central nervous system (CNS) that play complex and heterogeneous roles in brain development, homeostasis and disease. Since their vast involvement in health and disease is becoming increasingly recognized, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99852135ced24bd9f5a9ea568a46c5ca
http://edoc.mdc-berlin.de/23038/7/23038suppl.zip
http://edoc.mdc-berlin.de/23038/7/23038suppl.zip
Autor:
Henning, Lukas, Unichenko, Petr, Bedner, Peter, Steinhäuser, Christian, Henneberger, Christian
Publikováno v:
Neurochemical research 48(4), 1091-1099 (2023). doi:10.1007/s11064-022-03773-z
Astrocytes play a dual role in the brain. On the one hand, they are active signaling partners of neurons and can for instance control synaptic transmission and its plasticity. On the other hand, they fulfill various homeostatic functions such as clea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b47cf8fe5d3fc7d7debca72d2311d70b
https://pubmed.ncbi.nlm.nih.gov/36244037
https://pubmed.ncbi.nlm.nih.gov/36244037
Autor:
Julia Schneider, Johannes Weigel, Marie‐Theres Wittmann, Pavel Svehla, Sebastian Ehrt, Fang Zheng, Tarek Elmzzahi, Julian Karpf, Lucía Paniagua‐Herranz, Onur Basak, Arif Ekici, Andre Reis, Christian Alzheimer, Felipe Ortega de la O, Sabine Liebscher, Ruth Beckervordersandforth
Publikováno v:
The EMBO journal 41(11), e110409 (2022). doi:10.15252/embj.2021110409
Astrocytes are highly abundant in the mammalian brain, and their functions are of vital importance for all aspects of development, adaption, and aging of the central nervous system (CNS). Mounting evidence indicates the important contributions of ast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad920c92b77455d8f3447a120403285
https://doi.org/10.15252/embj.2021110409
https://doi.org/10.15252/embj.2021110409
Autor:
Kirsten Bohmbach, Nicola Masala, Eva M. Schönhense, Katharina Hill, André N. Haubrich, Andreas Zimmer, Thoralf Opitz, Heinz Beck, Christian Henneberger
Publikováno v:
Nature Communications 13(1), 7932 (2022). doi:10.1038/s41467-022-35620-8
Dendrites of hippocampal CA1 pyramidal cells amplify clustered glutamatergic input by activation of voltage-gated sodium channels and N-methyl-D-aspartate receptors (NMDARs). NMDAR activity depends on the presence of NMDAR co-agonists such as D-serin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c8eeecb37800295e64926a02448fd6d
Publikováno v:
Nature reviews / Neuroscience 21(10), 551-564 (2020). doi:10.1038/s41583-020-0361-8
Astrocytes functionally interact with neurons and with other brain cells. Although not electrically excitable, astrocytes display a complex repertoire of intracellular Ca2+ signalling that evolves in space and time within single astrocytes and across
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b086a0e03fe42b9139ea0b2af245918d
Autor:
Phillip C. Wong, Diana Wiesner, Francesco Roselli, Tobias M. Boeckers, Deniz Yilmazer-Hanke, Barbara Commisso, Linyun Tang, Albert C. Ludolph, Jochen H. Weishaupt, Najwa Ouali Alami, Luc Dupuis, David Bayer, Bernd Baumann, Thomas Wirth
Publikováno v:
Life science alliance 3(11), e201900571 (2020). doi:10.26508/lsa.201900571
Life Science Alliance
Life Science Alliance, Life Science Alliance LLC, 2020, 3 (11), pp.e201900571. ⟨10.26508/lsa.201900571⟩
Life Science Alliance, 2020, 3 (11), pp.e201900571. ⟨10.26508/lsa.201900571⟩
Life Science Alliance
Life Science Alliance, Life Science Alliance LLC, 2020, 3 (11), pp.e201900571. ⟨10.26508/lsa.201900571⟩
Life Science Alliance, 2020, 3 (11), pp.e201900571. ⟨10.26508/lsa.201900571⟩
Chemogenetic motoneuron excitation and astrocyte GPCR-Gi signaling restore blood–spinal cord barrier, disrupted in four ALS mouse models, revealing its role in disease progression but not initiation.
Blood–spinal cord barrier (BSCB) disrupti
Blood–spinal cord barrier (BSCB) disrupti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93218dfe1100975b7bc1fb24ea761df4
https://pub.dzne.de/record/164314
https://pub.dzne.de/record/164314
Autor:
Maria Angeliki S. Pavlou, Kevin Carvalho, Gaurav Jain, Didier Vieau, Patrícia I. Santos, Lucrezia Cellai, Thorsten Gnad, David Blum, Tiago F. Outeiro, Luc Buée, Andre Fischer, Alexander Pfeifer, Isabel Paiva
Publikováno v:
Glia
Glia, Wiley, 2019, 67 (12), pp.2329-2342. ⟨10.1002/glia.23688⟩
Glia, 2019, 67 (12), pp.2329-2342. ⟨10.1002/glia.23688⟩
Glia 67(12), 2329-2342 (2019). doi:10.1002/glia.23688
Glia, Wiley, 2019, 67 (12), pp.2329-2342. ⟨10.1002/glia.23688⟩
Glia, 2019, 67 (12), pp.2329-2342. ⟨10.1002/glia.23688⟩
Glia 67(12), 2329-2342 (2019). doi:10.1002/glia.23688
International audience; Adenosine A2A receptors (A2A R) are modulators of various physiological processes essential for brain homeostasis and fine synaptic tuning. In certain neurodegenerative conditions, notably Alzheimer's disease (AD), A2A Rs are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fccdc1fb931c1093242620a28c33f90e
https://www.hal.inserm.fr/inserm-02350068
https://www.hal.inserm.fr/inserm-02350068
Publikováno v:
European journal of neuroscience 44(1), 1734-1746 (2016). doi:10.1111/ejn.13271
The neural cell adhesion molecule (NCAM) plays important functional roles in development of the nervous system. We investigated the influence of a constitutive ablation of NCAM on the outcome of spinal cord injury. Transgenic mice lacking NCAM (NCAM-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6b786cf54e593b7515af97c5a37d09
https://doi.org/10.1111/ejn.13271
https://doi.org/10.1111/ejn.13271
Autor:
Savtchenko, Leonid P., Bard, Lucie, Jensen, Thomas P., Reynolds, James P., Kraev, Igor, Medvedev, Nikolay, Stewart, Michael G., Henneberger, Christian, Rusakov, Dmitri A.
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Nature Communications 9(1), 3554 (2018). doi:10.1038/s41467-018-05896-w
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Nature Communications 9(1), 3554 (2018). doi:10.1038/s41467-018-05896-w
Electrically non-excitable astroglia take up neurotransmitters, buffer extracellular K+ and generate Ca2+ signals that release molecular regulators of neural circuitry. The underlying machinery remains enigmatic, mainly because the sponge-like astroc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9f9b717c155df985308fb7b6adcea2dc
http://europepmc.org/articles/PMC6120909
http://europepmc.org/articles/PMC6120909
Autor:
Henneberger, Christian
Publikováno v:
The journal of physiology 595(6), 1917-1927 (2016). doi:10.1113/JP271958
The hippocampus is a key brain region in the pathophysiology of mesial temporal lobe epilepsy. Long-term changes of its architecture and function on the network and cellular level are well documented in epilepsy. Astrocytes can control many aspects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::33366225da7252e7c161c52c1ff7b401
https://europepmc.org/articles/PMC5350435/
https://europepmc.org/articles/PMC5350435/