Zobrazeno 1 - 10
of 41
pro vyhledávání: '"physiology [Action Potentials]"'
Autor:
Prateep Beed, Richard Kempter, Michael Brecht, John J. Tukker, Edvard I. Moser, Dietmar Schmitz
Publikováno v:
Physiological Reviews
Physiological reviews 102(2), 653-688 (2022). doi:10.1152/physrev.00042.2020
Physiological reviews 102(2), 653-688 (2022). doi:10.1152/physrev.00042.2020
The hippocampal formation is critically involved in learning and memory and contains a large proportion of neurons encoding aspects of the organism’s spatial surroundings. In the medial entorhinal cortex (MEC), this includes grid cells with their d
Autor:
Nicola Masala, Martin Pofahl, André N Haubrich, Khondker Ushna Sameen Islam, Negar Nikbakht, Maryam Pasdarnavab, Kirsten Bohmbach, Kunihiko Araki, Fateme Kamali, Christian Henneberger, Kurtulus Golcuk, Laura A Ewell, Sandra Blaess, Tony Kelly, Heinz Beck
Publikováno v:
Brain 146(6), 2399-2417 (2023). doi:10.1093/brain/awac455
Memory deficits are a debilitating symptom of epilepsy, but little is known about mechanisms underlying cognitive deficits. Here, we describe a Na+ channel-dependent mechanism underlying altered hippocampal dendritic integration, degraded place codin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbeaa2b524ee2be384bba35a7ff7c581
https://pub.dzne.de/record/258241
https://pub.dzne.de/record/258241
Publikováno v:
Cerebral Cortex (New York, NY)
Cerebral cortex 32(1), 76-92 (2021). doi:10.1093/cercor/bhab195
Cerebral cortex 32(1), 76-92 (2021). doi:10.1093/cercor/bhab195
The parasubiculum (PaS) is located within the parahippocampal region, where it is thought to be involved in the processing of spatial navigational information. It contains a number of functionally specialized neuron types including grid cells, head d
Publikováno v:
Nature Communications 13, 3934 (2022). doi:10.1038/s41467-022-31195-6
Almost seventy years after the discovery of the mechanisms of action potential generation, some aspects of their computational consequences are still not fully understood. Based on mathematical modeling, we here explore a type of action potential dyn
Autor:
Yacine Brahimi, Beate Knauer, Alan Tobias Price, Maria Jesus Valero-Aracama, Antonio Reboreda, Magdalena Sauvage, Motoharu Yoshida
Publikováno v:
eNeuro, 10(3):ENEURO.0479-22.2023
eNeuro 10(3), ENEURO.0479-22.2023 (2023). doi:10.1523/ENEURO.0479-22.2023
eNeuro 10(3), ENEURO.0479-22.2023 (2023). doi:10.1523/ENEURO.0479-22.2023
Persistent neuronal firing is often observed in working memory and temporal association tasks both in humans and animals, and is believed to retain necessary information in these tasks. We have reported that hippocampal CA1 pyramidal cells are able t
Publikováno v:
Neuron 110(12), 1884-1886 (2022). doi:10.1016/j.neuron.2022.05.019
In this issue of Neuron, Szabo et al. uncover a unique subtype of interneurons that is highly active during ripples but largely silent during theta oscillations. The study provides exciting new insights into the regulation and propagation of ripples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee41ea24aa86e5c68a1cda6332bcea70
Autor:
Pedro Belio-Mairal, Emmanuel Nivet, Laurie Arnaud, Alexander Dityatev, Santiago Rivera, Nikita Arnst, Laura García-González, Louise Greetham
Publikováno v:
Cells
Cells, 2021, 10 (7), pp.1705. ⟨10.3390/cells10071705⟩
Volume 10
Issue 7
Cells, Vol 10, Iss 1705, p 1705 (2021)
Cells 10(7), 1705 (2021). doi:10.3390/cells10071705 special issue: "Pluripotent Stem Cells for Regenerative Medicine"
Cells, MDPI, 2021, 10 (7), pp.1705. ⟨10.3390/cells10071705⟩
Cells, 2021, 10 (7), pp.1705. ⟨10.3390/cells10071705⟩
Volume 10
Issue 7
Cells, Vol 10, Iss 1705, p 1705 (2021)
Cells 10(7), 1705 (2021). doi:10.3390/cells10071705 special issue: "Pluripotent Stem Cells for Regenerative Medicine"
Cells, MDPI, 2021, 10 (7), pp.1705. ⟨10.3390/cells10071705⟩
International audience; For some time, it has been accepted that the β-site APP cleaving enzyme 1 (BACE1) and the γ-secretase are two main players in the amyloidogenic processing of the β-amyloid precursor protein (APP). Recently, the membrane-typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7770ce90448455c7c181fcd8dbf6931e
https://hal.science/hal-03423990
https://hal.science/hal-03423990
Autor:
Zafeiriou, Maria-Patapia, Bao, Guobin, Hudson, James, Halder, Rashi, Blenkle, Alica, Schreiber, Marie-Kristin, Fischer, Andre, Schild, Detlev, Zimmermann, Wolfram-Hubertus
Publikováno v:
Nature Communications
Nature Communications 11(1), 3791 (2020). doi:10.1038/s41467-020-17521-w
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications 11(1), 3791 (2020). doi:10.1038/s41467-020-17521-w
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Brain organoids are promising tools for disease modeling and drug development. For proper neuronal network formation excitatory and inhibitory neurons as well as glia need to co-develop. Here, we report the directed self-organization of human induced
Publikováno v:
Cells
Cells, Vol 9, Iss 2, p 365 (2020)
Cells 9(2), 365 (2020). doi:10.3390/cells9020365
Cells, 9(2):365
Cells, Vol 9, Iss 2, p 365 (2020)
Cells 9(2), 365 (2020). doi:10.3390/cells9020365
Cells, 9(2):365
Persistent neural activity has been observed in vivo during working memory tasks, and supports short-term (up to tens of seconds) retention of information. While synaptic and intrinsic cellular mechanisms of persistent firing have been proposed, unde
Autor:
Michael Brecht, Albert K. Lee
Publikováno v:
Trends in neurosciences 41(6), 385-403 (2018). doi:10.1016/j.tins.2018.03.014
Intracellular recording allows measurement and perturbation of the membrane potential of identified neurons with sub-millisecond and sub-millivolt precision. This gives intracellular recordings a unique capacity to provide rich information about indi