Application of Quantitative Motor Assessments in Friedreich Ataxia and Evaluation of Their Relation to Clinical Measures

Autor: Matthis Synofzik, Claire Didszun, Imis Dogan, Robin Schubert, Jörg B. Schulz, Thomas Klockgether, Kathrin Reetz, Ludger Schöls, Ralf Reilmann, Christian Hohenfeld, Ilaria Giordano

Publikováno v: The Cerebellum 18(5), 896-909 (2019). doi:10.1007/s12311-019-01073-x

Friedreich's ataxia (FRDA) is a rare autosomal-recessive slowly progressive neurodegenerative disorder. As common clinical measures for this devastating disease lack sensitivity, we explored whether (a) the quantitative motor assessments of the Q-Mot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afba26d581f9c10e3ac8d7db5961e836
https://doi.org/10.1007/s12311-019-01073-x

The Impact of Visual Cues, Reward, and Motor Feedback on the Representation of Behaviorally Relevant Spatial Locations in Primary Visual Cortex

Autor: Pakan, Janelle M P, Currie, Stephen P, Fischer, Lukas, Rochefort, Nathalie L

Publikováno v: Pakan, J M P, Currie, S P, Fischer, L & Rochefort, N L 2018, ' The Impact of Visual Cues, Reward, and Motor Feedback on the Representation of Behaviorally Relevant Spatial Locations in Primary Visual Cortex ', Cell Reports, vol. 24, no. 10, pp. 2521-2528 . https://doi.org/10.1016/j.celrep.2018.08.010
Cell Reports, Vol 24, Iss 10, Pp 2521-2528 (2018)
Cell reports 24(10), 2521-2528 (2018). doi:10.1016/j.celrep.2018.08.010

Summary: The integration of visual stimuli and motor feedback is critical for successful visually guided navigation. These signals have been shown to shape neuronal activity in the primary visual cortex (V1), in an experience-dependent manner. Here,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::21854d4009b3b1bc865ab982263b431b
https://www.pure.ed.ac.uk/ws/files/75240547/1_s2.0_S2211124718312646_main_1_.pdf

Dissociation of Neural Networks for Predisposition and for Training-Related Plasticity in Auditory-Motor Learning

Autor: Sibylle C. Herholz, Robert J. Zatorre, Emily B. J. Coffey, Christo Pantev

Publikováno v: Cerebral cortex 26(7), 3125-3134 (2015). doi:10.1093/cercor/bhv138

Skill learning results in changes to brain function, but at the same time individuals strongly differ in their abilities to learn specific skills. Using a 6-week piano-training protocol and pre- and post-fMRI of melody perception and imagery in adult

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265c56a51d8ea24bcd3532f33b2c4759
https://europepmc.org/articles/PMC4898668/

Region and task-specific activation of Arc in primary motor cortex of rats following motor skill learning

Autor: S. Mann, Jonas A. Hosp, Michael E. Calhoun, Bettina M. Wegenast-Braun, A.R. Luft

Publikováno v: Neuroscience 250, 557-564 (2013). doi:10.1016/j.neuroscience.2013.06.060
Neuroscience

Motor learning requires protein synthesis within the primary motor cortex (M1). Here, we show that the immediate early gene Arc/Arg3.1 is specifically induced in M1 by learning a motor skill. Arc mRNA was quantified using a fluorescent in situ hybrid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3758e6bed48ef6228bf96a1c5a66f157
https://pub.dzne.de/record/137050

Shift of preferred directions of premotor cortical cells with arm movements performed across the workspace

Autor: P. B. Johnson, Yves Burnod, C Galli, Stefano Ferraina, Roberto Caminiti

Publikováno v: Experimental Brain Research. 83

The activity of 156 neurons was recorded in the premotor cortex (Weinrich and Wise 1982) and in an adjoining rostral region of area 6 (area 6 DR; Barbas and Pandya 1987) while monkeys made visually-guided arm movements of similar direction within dif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa2a27581991b9a0f069bbb35253278c
https://doi.org/10.1007/bf00232214