Spinal TNF-α receptor 1 is differentially required for phrenic long-term facilitation (pLTF) over the course of motor neuron death in adult rats

Autor: Ryan D. Lewis, Amy N. Keilholz, Catherine L. Smith, Ethan A. Burd, Nicole L. Nichols

Publikováno v: Frontiers in Physiology, Vol 15 (2024)

IntroductionIntrapleural injections of cholera toxin B conjugated to saporin (CTB-SAP) result in selective respiratory (e.g., phrenic) motor neuron death and mimics aspects of motor neuron disease [(e.g., amyotrophic lateral sclerosis (ALS) and spina

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Spinal TNF-α receptor 1 is differentially required for phrenic long-term facilitation (pLTF) over the course of motor neuron death in adult rats.

Autor: Lewis RD; Department of Biological Chemistry, Grinnell College, Grinnell, IA, United States., Keilholz AN; Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, MO, United States.; Department of Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, MO, United States., Smith CL; Department of Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, MO, United States., Burd EA; Department of Biology, Seton Hill University, Greensburg, PA, United States., Nichols NL; Department of Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, MO, United States.; Department of Medical Pharmacology and Physiology, School of Medicine, University of Missouri, Columbia, MO, United States.; Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO, United States.

Publikováno v: Frontiers in physiology [Front Physiol] 2024 Dec 05; Vol. 15, pp. 1488951. Date of Electronic Publication: 2024 Dec 05 (Print Publication: 2024).