Antigen-Antibody Affinity for Dry Eye Biomarkers by Label Free Biosensing. Comparison with the ELISA Technique

Autor: Maríafe Laguna, Miguel Holgado, Ana L. Hernandez, Beatriz Santamaría, Alvaro Lavín, Javier Soria, Tatiana Suarez, Carlota Bardina, Mónica Jara, Francisco J. Sanza, Rafael Casquel

Publikováno v: Sensors, Vol 15, Iss 8, Pp 19819-19829 (2015)

The specificity and affinity of antibody-antigen interactions is a fundamental way to achieve reliable biosensing responses. Different proteins involved with dry eye dysfunction: ANXA1, ANXA11, CST4, PRDX5, PLAA and S100A6; were validated as biomarke

Externí odkaz: https://doaj.org/article/8bcfe6617f9542b39615ee35b774f0af

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Antigen-Antibody Affinity for Dry Eye Biomarkers by Label Free Biosensing. Comparison with the ELISA Technique

Autor: Miguel Holgado, Beatriz Santamaría, Ana L. Hernandez, Maríafe Laguna, Álvaro Lavín, Tatiana Suárez, Rafael Casquel, Mónica Jara, Francisco J. Sanza, Javier Soria, Carlota Bardina

Publikováno v: Sensors, Vol 15, Iss 8, Pp 19819-19829 (2015)
Sensors, ISSN 1424-8220, 2015, Vol. 15
Sensors
Volume 15
Issue 8
Pages 19819-19829
Sensors (Basel, Switzerland)
Archivo Digital UPM
Universidad Politécnica de Madrid

The specificity and affinity of antibody-antigen interactions is a fundamental way to achieve reliable biosensing responses. Different proteins involved with dry eye dysfunction: ANXA1, ANXA11, CST4, PRDX5, PLAA and S100A6
were validated as biom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c9578eb0cd9753d6a75dcc51e5e8452
https://doi.org/10.3390/s150819819

Optimization of Dengue immunoassay by label-free interferometric optical detection method

Autor: Francisco J. Sanza, M.F. Laguna, Rafael Casquel, Miguel Holgado, Ana López, Álvaro Lavín

Publikováno v: Sensors, ISSN 1424-8220, 2014-04, Vol. 14
Archivo Digital UPM
Universidad Politécnica de Madrid
Sensors (Basel, Switzerland)
Sensors, Vol 14, Iss 4, Pp 6695-6700 (2014)

In this communication we report a direct immunoassay for detecting dengue virus by means of a label-free interferometric optical detection method. We also demonstrate how we can optimize this sensing response by adding a blocking step able to signifi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac8ed610ecde77f01c54cc2b0cca8db5
https://oa.upm.es/40118/

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