An Insight into the Degradation Processes of the Anti-Hypertensive Drug Furosemide

Autor: Micaela Giannetti, Viviana Claudia Canale, Laura Micheli, Maurizio Fiori, Claudia Mazzuca, Antonio Palleschi

Publikováno v: Molecules, Vol 28, Iss 1, p 381 (2023)

Furosemide (FUR), an active pharmaceutical ingredient (API) belonging to a group of drugs known as loop diuretics, has widespread use, but, is characterized by a strong instability to light, which causes chemical transformations that could give a yel

Externí odkaz: https://doaj.org/article/75ac54e9276745b68077f6da092400fb

Daisy-Chaining Photo- and Thermal Chemistry: Multistep Continuous Flow Synthesis of Visible-Light-Mediated Photochemistry with a High-Temperature Cascade Reaction

Autor: Luke D. Elliott, Alastair J. J. Lennox, Kevin I. Booker-Milburn

Publikováno v: Elliott, L D, Booker-Milburn, K I & Lennox, A J J 2021, ' Daisy-Chaining Photo-and Thermal Chemistry : Multi-Step Continuous Flow Synthesis of Visible-Light Mediated Photo-chemistry with a High Temperature Cascade Reaction ', Organic Process Research & Development, vol. 25, no. 8, pp. 1943-1949 . https://doi.org/10.1021/acs.oprd.1c00187

A highly efficient visible light mediated photochemical [2+2] cycloaddition is coupled with an atom economic thermal cascade reaction in a continuous flow process. By moving the photochemistry from UV to visible it is made more energy efficient and c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d1854af8a70b571a011613162e9411
https://doi.org/10.1021/acs.oprd.1c00187

Multiple Light Control Mechanisms in ATP‐Fueled Non‐equilibrium DNA Systems

Autor: Jie Deng, Henning J. Jessen, Dominik Bezold, Andreas Walther

Publikováno v: Angewandte Chemie International Edition
Angewandte Chemie (International Ed. in English)

Fuel‐driven self‐assemblies are gaining ground for creating autonomous systems and materials, whose temporal behavior is preprogrammed by a reaction network. However, up to now there has been a lack of simple external control mechanisms of the tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88a67519b917cdb9382396f46c5cf30a
https://doi.org/10.1002/ange.202003102

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A Self‐immolative Molecular Beacon for Amplified Nucleic Acid Detection

Autor: Magdalena Roth, Oliver Seitz

Publikováno v: Chemistry – A European Journal
Chemistry (Weinheim an Der Bergstrasse, Germany)

Fluorogenic hybridization probes allow the detection of RNA and DNA sequences in homogeneous solution. Typically, one target molecule activates the fluorescence of a single probe molecule. This limits the sensitivity of nucleic acid detection. Herein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b61efa296d40a397807745f5c06cc067
http://edoc.hu-berlin.de/18452/25261