Zobrazeno 1 - 10
of 7 404
pro vyhledávání: '"phosphoproteomics"'
Publikováno v:
Zhongliu Fangzhi Yanjiu, Vol 51, Iss 10, Pp 820-830 (2024)
ObjectiveTo analyze the differences in the expressions of the total and phosphorylated proteins in human colon cancer HCT116 cells after the knockout (KO) of retinoic acid-induced protein 16 (RAI16) and explore the possible mechanism and related sign
Externí odkaz:
https://doaj.org/article/330c58fa250c4759bc917d83f4f435ce
Autor:
Jonathan Samuel Achter, Estefania Torres Vega, Andrea Sorrentino, Konstantin Kahnert, Katrine Douglas Galsgaard, Pablo Hernandez-Varas, Michael Wierer, Jens Juul Holst, Jørgen Frank Pind Wojtaszewski, Robert William Mills, Rasmus Kjøbsted, Alicia Lundby
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-16 (2024)
Abstract Background Insulin signaling regulates cardiac substrate utilization and is implicated in physiological adaptations of the heart. Alterations in the signaling response within the heart are believed to contribute to pathological conditions su
Externí odkaz:
https://doaj.org/article/7f7d63dc57134c099c235fc73a14ffc2
Autor:
Pengfei Gan, Chunlei Tang, Yi Lu, Chenrong Ren, Hojjatollah Rabbani Nasab, Xufeng Kun, Xiaodong Wang, Liangzhuang Li, Zhensheng Kang, Xiaojie Wang, Jianfeng Wang
Publikováno v:
Stress Biology, Vol 4, Iss 1, Pp 1-15 (2024)
Abstract Protein phosphorylation plays an important role in immune signaling transduction in plant resistance to pathogens. Wheat stripe rust, caused by Puccinia striiformis f. sp. tritici (Pst), severely devastates wheat production. Nonetheless, the
Externí odkaz:
https://doaj.org/article/6ee47459863b46b9a59b21ccafe3a5cb
Autor:
Denys Oliinyk, Andreas Will, Felix R Schneidmadel, Maximilian Böhme, Jenny Rinke, Andreas Hochhaus, Thomas Ernst, Nina Hahn, Christian Geis, Markus Lubeck, Oliver Raether, Sean J Humphrey, Florian Meier
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 8, Pp 972-995 (2024)
Abstract Mass spectrometry has revolutionized cell signaling research by vastly simplifying the analysis of many thousands of phosphorylation sites in the human proteome. Defining the cellular response to perturbations is crucial for further illumina
Externí odkaz:
https://doaj.org/article/6e562a7488544cb3987d5a02f54ee0a2
Autor:
Chao Song, Ganggang Wang, Mengmeng Liu, Siyang Han, Meiyuan Dong, Maozhen Peng, Wenquan Wang, Yicun Wang, Yaolin Xu, Liang Liu
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Objective This study aims to elucidate the functional role of IQGAP1 phosphorylation modification mediated by the SOX4/MAPK1 regulatory axis in developing pancreatic cancer through phosphoproteomics analysis. Methods Proteomics and phosphopr
Externí odkaz:
https://doaj.org/article/1ad6203a921d4bd798ff220110f11655
Publikováno v:
Heliyon, Vol 10, Iss 22, Pp e40060- (2024)
The mosquito fat body is the principal source of yolk protein precursors (YPP) during mosquito egg development in female Aedes aegypti. To better understand the metabolic and signaling pathways involved in mosquito reproduction, we investigated chang
Externí odkaz:
https://doaj.org/article/d4329369060f41178a026f3d6a1a1bed
Autor:
YuYing Zheng, Yu Liu, Yan Jiang, Zhihua Li, Qiang Zhang, Qing Yu, Jun Liu, Zhimin Yang, Yu Chen
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 286, Iss , Pp 117220- (2024)
Seashore paspalum (Paspalum vaginatum) is a warm-season and perennial turfgrass and is known for its cadmium (Cd)-stress tolerance. Here, a Phosphoproteomics analysis was performed to examine the key proteins relating to Cd tolerance in seashore pasp
Externí odkaz:
https://doaj.org/article/a977657d8c0f43b5958306d07e1c323f
Autor:
Mingzhu Fan, Jin Hu, Xiaoyan Xu, Jia Chen, Wenwen Zhang, Xiaoping Zheng, Jinheng Pan, Wei Xu, Shan Feng
Publikováno v:
Heliyon, Vol 10, Iss 19, Pp e38182- (2024)
Hepatocellular Carcinoma (HCC) is a serious primary solid tumor that is prevalent worldwide. Due to its high mortality rate, it is crucial to explore both early diagnosis and advanced treatment for HCC. In recent years, multi-omics approaches have em
Externí odkaz:
https://doaj.org/article/9d461717c5964440acd1115ac8e755fc
Autor:
Weronika E. Borek, Luis Nobre, S. Federico Pedicona, Amy E. Campbell, Josie A. Christopher, Nazrath Nawaz, David N. Perkins, Pedro Moreno-Cardoso, Janet Kelsall, Harriet R. Ferguson, Bela Patel, Paolo Gallipoli, Andrea Arruda, Alex J. Ambinder, Andrew Thompson, Andrew Williamson, Gabriel Ghiaur, Mark D. Minden, John G. Gribben, David J. Britton, Pedro R. Cutillas, Arran D. Dokal
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105316- (2024)
Summary: Background: Acute myeloid leukaemia (AML) is a bone marrow malignancy with poor prognosis. One of several treatments for AML is midostaurin combined with intensive chemotherapy (MIC), currently approved for FLT3 mutation-positive (FLT3-MP) A
Externí odkaz:
https://doaj.org/article/c1ed1c39383540cb899802e9a5af0c25
Autor:
Juan Manuel Gomez, Hendrik Nolte, Elisabeth Vogelsang, Bipasha Dey, Michiko Takeda, Girolamo Giudice, Miriam Faxel, Theresa Haunold, Alina Cepraga, Robert P Zinzen, Marcus Krüger, Evangelia Petsalaki, Yu-Chiun Wang, Maria Leptin
Publikováno v:
eLife, Vol 13 (2024)
The initially homogeneous epithelium of the early Drosophila embryo differentiates into regional subpopulations with different behaviours and physical properties that are needed for morphogenesis. The factors at top of the genetic hierarchy that cont
Externí odkaz:
https://doaj.org/article/b0c680df25ca4144b7b8c28327ad121a