Zobrazeno 1 - 10
of 46
pro vyhledávání: '"phosphatase and tensin homologue(pten)"'
Publikováno v:
Guoji Yanke Zazhi, Vol 24, Iss 1, Pp 24-29 (2024)
AIM: To study the protective effect of fenofibrate on diabetic retinal neurodegeneration and observe its effect on miR-26a-5p and its target gene PTEN in the retinal of diabetic mice.METHODS: Diabetic mice models were established and they were gavage
Externí odkaz:
https://doaj.org/article/f8a4e32391ee4ee9b4336bf394c42b9b
Akademický článek
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Autor:
So-Youn Kim, Takeshi Kurita
Publikováno v:
European Medical Journal, Vol 3, Iss 2, Pp 119-125 (2018)
The immature oocytes within primordial follicles are arrested at Prophase I of meiosis and remain dormant until awakened by an increase in intracellular levels of phosphatidylinositol (3,4,5)-trisphosphate (PIP3). Oocyte PIP3 level is determined by t
Externí odkaz:
https://doaj.org/article/e1a430a0a9ef49828e7278998c28c811
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-14 (2018)
Abstract Regulation of the PI-3 kinase (PI3K)/Akt signalling pathway is essential for maintaining the integrity of fundamental cellular processes, cell growth, survival, death and metabolism, and dysregulation of this pathway is implicated in the dev
Externí odkaz:
https://doaj.org/article/e66e0438c073488981f1d22adb2c096f
Autor:
Angeliki eMavrantoni, Veronika eThallmair, Michael G Leitner, Daniela N Schreiber, Dominik eOliver, Christian R Halaszovich
Publikováno v:
Frontiers in Pharmacology, Vol 6 (2015)
Voltage sensitive phosphatases (VSPs), including engineered voltage sensitive PTEN, are excellent tools to rapidly and reversibly alter the phosphoinositide (PI) content of the plasma membrane in vivo and study the tumor suppressor PTEN. However, wid
Externí odkaz:
https://doaj.org/article/d772dd7048914ed28b2e969b85f77661
Publikováno v:
Journal of Cancer
HES1 is a transcriptional repressor involved in cell differentiation and proliferation as well as in various cancer developments, but its expression pattern and biological roles in breast cancer have not been examined. In this study, we assessed HES1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::409e3f30b1213f287730b217f242ea7f
https://doi.org/10.7150/jca.22319
https://doi.org/10.7150/jca.22319
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-14 (2018)
Molecular Cancer
Molecular Cancer
© 2018 The Author(s). Regulation of the PI-3 kinase (PI3K)/Akt signalling pathway is essential for maintaining the integrity of fundamental cellular processes, cell growth, survival, death and metabolism, and dysregulation of this pathway is implica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec1ac0a8bde14f80a4710e23c7cc4eb
https://doi.org/10.1186/s12943-018-0803-3
https://doi.org/10.1186/s12943-018-0803-3
Autor:
Hiroshi Wada, H. Nagano, Hidetoshi Eguchi, Shigeru Marubashi, S. Kobayashi, Masaki Mori, Akira Tomokuni, Yuichiro Doki, Masahiro Tanemura, Yoshito Takeda, Yoshito Tomimaru, K Umeshita
Publikováno v:
British Journal of Cancer
Background: We reported recently the clinical efficiency of interferon (IFN)-α/5-fluorouracil (5-FU) combination therapy in advanced hepatocellular carcinoma (HCC). However, prediction of the response to the combination therapy remains unsatisfactor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24bd5ca4842a843c7f0fc54f01acc15d
http://europepmc.org/articles/PMC2990590
http://europepmc.org/articles/PMC2990590
Autor:
Christian R. Halaszovich, Angeliki Mavrantoni, Dominik Oliver, Michael G. Leitner, Veronika Thallmair, Daniela N. Schreiber
Publikováno v:
Frontiers in Pharmacology, Vol 6 (2015)
Frontiers in Pharmacology
Frontiers in Pharmacology
Voltage sensitive phosphatases (VSPs), including engineered voltage sensitive PTEN, are excellent tools to rapidly and reversibly alter the phosphoinositide (PI) content of the plasma membrane in vivo and study the tumor suppressor PTEN. However, wid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e7e8f89d6c64078d0156c54309b7d8
https://doi.org/10.3389/fphar.2015.00068
https://doi.org/10.3389/fphar.2015.00068
Publikováno v:
Bioscience Reports, Vol 35, Iss 1, p e00174 (2015)
Bioscience Reports
Bioscience Reports
Apoptosis mediates the precise and programmed natural death of neurons and is a physiologically important process in neurogenesis during maturation of the central nervous system. However, premature apoptosis and/or an aberration in apoptosis regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d5cc0036ace835e990f23edeb46f15
https://doi.org/10.1042/bsr20140104
https://doi.org/10.1042/bsr20140104