Zobrazeno 1 - 10
of 332
pro vyhledávání: '"phosphatase and tensin homolog (PTEN)"'
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background This study was designed to investigate the mechanism by which miR-30a-5p mediates cardiomyocyte apoptosis after acute myocardial infarction (AMI) induced by hypoxia/reoxygenation (H/R). Methods Differentially expressed miRNAs were
Externí odkaz:
https://doaj.org/article/aa13dd7aef844144895c47a7b3cf4c5e
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Disruption of inhibitory interneurons is common in the epileptic brain and is hypothesized to play a pivotal role in epileptogenesis. Abrupt disruption and loss of interneurons is well-characterized in status epilepticus models of epilepsy, however,
Externí odkaz:
https://doaj.org/article/224eff835e1048a9a1fa3c42fe47ee04
Autor:
Wei Li, Chuanyu Yang, Zhuo Cheng, Yuanyuan Wu, Sihan Zhou, Xiaowei Qi, Yi Zhang, Jinhui Hu, Mingjin Xie, Ceshi Chen
Publikováno v:
MedComm, Vol 5, Iss 8, Pp n/a-n/a (2024)
Abstract Colorectal cancer (CRC) is one of the most common malignancies worldwide. In the clinical realm, platinum‐based drugs hold an important role in the chemotherapy of CRC. Nonetheless, a multitude of patients, due to tumor protein 53 (TP53) g
Externí odkaz:
https://doaj.org/article/b58a674ecc524aa083d0d3a7f9c21779
Publikováno v:
Shanghai Jiaotong Daxue xuebao. Yixue ban, Vol 43, Iss 11, Pp 1339-1347 (2023)
Objective·To study the effect of phosphatase and tensin homolog on chromosome 10 (PTEN) on alternative splicing of forkhead box M1 (FoxM1), and its impact on tumor cell migration.Methods·PTEN was knocked down by short hairpin RNA (shRNA) in human e
Externí odkaz:
https://doaj.org/article/2d708e964c334e3aaa6cb9cc914202e7
Publikováno v:
Medicina, Vol 60, Iss 11, p 1744 (2024)
Background and Objectives: Type 1 Diabetes Mellitus (T1DM) is an autoimmune disease with T cell-mediated pathogenesis of pancreatic β-cell destruction, leading to insulin deficiency. MicroRNAs such as miR-223 and miR-106b, along with PTEN, have been
Externí odkaz:
https://doaj.org/article/44095f71cd974799902a700ac25651eb
Autor:
Zhao Wang, Menghan Luo, Qian Liang, Ke Zhao, Yuelin Hu, Wei Wang, Xiangling Feng, Bolang Hu, Jianjin Teng, Tianyi You, Ran Li, Zhengkai Bao, Wenhao Pan, Tielong Yang, Chao Zhang, Ting Li, Xiaobao Dong, Xianfu Yi, Ben Liu, Li Zhao, Miaoxin Li, Kexin Chen, Weihong Song, Jilong Yang, Mulin Jun Li
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-32 (2023)
Abstract Background The high mutation rate throughout the entire melanoma genome presents a major challenge in stratifying true driver events from the background mutations. Numerous recurrent non-coding alterations, such as those in enhancers, can sh
Externí odkaz:
https://doaj.org/article/ea2c5d7f313e4e34877e64882a16ffd9
Akademický článek
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Akademický článek
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Autor:
Rongguiyi Zhang, Jiyuan Ai, Jiakun Wang, Chi sun, Hongcheng Lu, Aoxiao He, Min Li, Yuting Liao, Jun Lei, Fan Zhou, Linquan Wu, Wenjun Liao
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-16 (2022)
Abstract Background NCAPG, non-SMC subunit in the concentrate I complex, might promote the proliferation of hepatocellular carcinoma (HCC), but the mechanism is unclear. The aim of this study was to explore how NCAPG affects PTEN to influence the pro
Externí odkaz:
https://doaj.org/article/76aa9bd662394325aa798ccda259329b
Akademický článek
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