Zobrazeno 1 - 10
of 2 264
pro vyhledávání: '"phenome"'
Autor:
Edalatifar, Mohammad, Shafi, Jana, Khalid, Majdi, Baro, Manuel, Sheremet, Mikhail A., Ghalambaz, Mohammad
Publikováno v:
International Journal of Numerical Methods for Heat & Fluid Flow, 2024, Vol. 34, Issue 8, pp. 3107-3130.
Externí odkaz:
http://www.emeraldinsight.com/doi/10.1108/HFF-11-2023-0678
Autor:
Rui Yin, Maxime Wack, Claire Hassen-Khodja, Michael T. McDuffie, Geraldine Bliss, Elizabeth J. Horn, Cartik Kothari, Brittany McLarney, Rebecca Davis, Kristen Hanson, Megan O’Boyle, Catalina Betancur, Paul Avillach
Publikováno v:
Molecular Autism, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Background Phelan-McDermid syndrome (PMS) is a rare neurodevelopmental disorder caused by 22q13 deletions that include the SHANK3 gene or pathogenic sequence variants in SHANK3. It is characterized by global developmental delay, intellectual
Externí odkaz:
https://doaj.org/article/6a99ab8229bd44dfa398029474c7791b
Autor:
Yao Dong, An-qun Hu, Bai-xue Han, Meng-ting Cao, Hai-yan Liu, Zong-guang Li, Qing Li, Ying-jie Zheng
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract Background Observational studies have revealed associations between maternal lipid metabolites and gestational diabetes mellitus (GDM). However, whether these associations are causal remain uncertain. Objective To evaluate the causal relatio
Externí odkaz:
https://doaj.org/article/0391a265412749b7ad3827ca2dcbed33
Publikováno v:
Immunological Medicine, Pp 1-10 (2024)
Disorders associated with the immune system burden multiple organs, although the shared biology exists across the diseases. Preceding family-based studies reveal that immune diseases are heritable to varying degrees, providing the basis for immunogen
Externí odkaz:
https://doaj.org/article/121486d690f64619b84d779c49e3bc06
Autor:
Wan-Hsuan Chou, Lu-Chun Chen, Henry Sung-Ching Wong, Ching-Hsuan Chao, Hou-Wei Chu, Wei-Chiao Chang
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Background The human leukocyte antigen (HLA) genes, exhibiting significant genetic diversity, are associated with susceptibility to various clinical diseases and diverse in drug responses. High costs of HLA sequencing and the population-spec
Externí odkaz:
https://doaj.org/article/5d714eba63554e35ae434c40769a9312
Autor:
Mengjie Zhong, Wenjie Xu, Pan Tian, Qin Zhang, Zixian Wang, Limiao Liang, Qixiang Zhang, Yuehong Yang, Ying Lu, Gong‐Hong Wei
Publikováno v:
Advanced Science, Vol 11, Iss 32, Pp n/a-n/a (2024)
Abstract Genetic and epigenetic alterations are cancer hallmark characteristics. However, the role of inherited cancer predisposition alleles in co‐opting lineage factor epigenetic reprogramming and tumor progression remains elusive. Here the FinnG
Externí odkaz:
https://doaj.org/article/52b2215bb66f4b908aa3592e93dfdd0d
Publikováno v:
Heliyon, Vol 10, Iss 16, Pp e35649- (2024)
Background: Smoking is a widespread behavior, while the relationship between smoking and various diseases remains a topic of debate. Objective: We conducted analysis to further examine the identified associations and assess potential causal relations
Externí odkaz:
https://doaj.org/article/f324f286dc97402488e4d86a09225b3e
Autor:
Yifei Cheng, Lang Wu, Junyi Xin, Shuai Ben, Silu Chen, Huiqin Li, Lingyan Zhao, Meilin Wang, Gong Cheng, Mulong Du
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Early-onset prostate cancer (EOPC, ≤ 55 years) has a unique clinical entity harboring high genetic risk, but the majority of EOPC patients still substantial opportunity to be early-detected thus suffering an unfavorable prognosi
Externí odkaz:
https://doaj.org/article/fbbb3387f0cb4e768eba0026b4e11c62
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-15 (2024)
Abstract Background Male-pattern baldness (MPB) is the most common cause of hair loss in men. It can be categorized into three types: type 2 (T2), type 3 (T3), and type 4 (T4), with type 1 (T1) being considered normal. Although various MPB-associated
Externí odkaz:
https://doaj.org/article/d53c906b15c44335a0e6cfb284ada755
Autor:
Young Chan Lee, Sang-Hyuk Jung, Manu Shivakumar, Soojin Cha, Woong-Yang Park, Hong-Hee Won, Young-Gyu Eun, Penn Medicine Biobank, Dokyoon Kim
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Numerous observational studies have highlighted associations of genetic predisposition of head and neck squamous cell carcinoma (HNSCC) with diverse risk factors, but these findings are constrained by design limitations of observa
Externí odkaz:
https://doaj.org/article/1ae348504cf743f89ce320ee4fcb2717