Zobrazeno 1 - 10
of 431
pro vyhledávání: '"phenol-soluble modulins"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
BackgroundStaphylococcus epidermidis is an important conditionally pathogenic bacterium. SarZ, belonging to the SarA family protein, has been demonstrated in S. aureus to promote the expression of invasive virulence factors while inhibiting biofilm f
Externí odkaz:
https://doaj.org/article/79cebf02eb494b39a71e22e245ec8f0c
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Staphylococcus aureus secretes phenol-soluble modulins (PSMs), a family of small, amphipathic, secreted peptides with multiple biologic activities. Community-acquired S. aureus strains produce high levels of PSMs in planktonic cultures, and
Externí odkaz:
https://doaj.org/article/160443d1516d43dda288430a463693e7
Autor:
Matthew K. Howard, Karlie R. Miller, Brian S. Sohn, Jeremy J. Ryan, Andy Xu, Meredith E. Jackrel
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Phenol-soluble modulins (PSMs) are the primary proteinaceous component of Staphylococcus aureus biofilms. Residence in the protective environment of biofilms allows bacteria to rapidly evolve and acquire antimicrobial resistance, which can l
Externí odkaz:
https://doaj.org/article/61adf2fa236b4edabda0ec692c3ce899
Akademický článek
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Publikováno v:
Biomimetics, Vol 8, Iss 6, p 459 (2023)
Since the proposal of the brainstem axis theory, increasing research attention has been paid to the interactions between bacterial amyloids produced by intestinal flora and the amyloid β−protein (Aβ) related to Alzheimer’s disease (AD), and it
Externí odkaz:
https://doaj.org/article/eae5102dc33a4197a616783f700f2484
Akademický článek
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Autor:
Alexia Damour, Brandon Robin, Luc Deroche, Lauranne Broutin, Nicolas Bellin, Julien Verdon, Gérard Lina, Franck Marie Leclère, Magali Garcia, Julie Cremniter, Nicolas Lévêque, Charles Bodet
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 2474-2492 (2021)
Staphylococcus aureus is a skin commensal microorganism commonly colonizing healthy humans. Nevertheless, S. aureus can also be responsible for cutaneous infections and contribute to flare-up of inflammatory skin diseases such as atopic dermatitis (A
Externí odkaz:
https://doaj.org/article/0963c36f14b94250847545240cd2a698
Autor:
Anke Siegmund, Muhammad Awais Afzal, Felix Tetzlaff, Daniela Keinhörster, Fabio Gratani, Kerstin Paprotka, Martin Westermann, Sandor Nietzsche, Christiane Wolz, Martin Fraunholz, Christian A. Hübner, Bettina Löffler, Lorena Tuchscherr
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 1186-1198 (2021)
A large proportion of clinical S. aureus isolates that carry an inactive Agr system are associated with persistent infection that is difficult to treat. Once S. aureus is inside the bloodstream, it can cross the endothelial barrier and invade almost
Externí odkaz:
https://doaj.org/article/d2be581b9a5d43d987b9dcb1ebf0c0ca
Autor:
Kaitlyn Grando, Lauren K. Nicastro, Sarah A. Tursi, Jaime De Anda, Ernest Y. Lee, Gerard C. L. Wong, Çağla Tükel
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The bacterial amyloid curli, produced by Enterobacteriales including Salmonella species and Escherichia coli, is implicated in the pathogenesis of several complex autoimmune diseases. Curli binds to extracellular DNA, and these complexes drive autoim
Externí odkaz:
https://doaj.org/article/87edc39e6510410cb2ecc65a785cf741
Autor:
Elisabeth Hodille, Laetitia Beraud, Séverine Périan, Valentine Berti, Michèle Bes, Anne Tristan, Emilie Blond, Gérard Lina, Oana Dumitrescu
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 1 (2022)
ABSTRACT Staphylococcus aureus (SA) is a major human pathogen producing virulence factors, such as Panton-Valentine-leucocidin (PVL), alpha-hemolysin (Hla), and phenol-soluble-modulins alpha (PSMα), including delta-hemolysin (Hld). Unlike oxacillin,
Externí odkaz:
https://doaj.org/article/e886c1004d16456480a57e10c9a9ca93