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pro vyhledávání: '"pharmacology [Thiazolidines]"'
Autor:
Niva Natan, Lili Wu, Victoria Nahum, Abraham Fisher, Eitan Gershonov, Nira Bar-Ner, Hanoch Elkon, Rodrigo Medeiros, Frank M. LaFerla, Ilya Bezprozvanny, Daniel A. Ryskamp, Rachel Brandeis
Publikováno v:
Fisher, Abraham; Bezprozvanny, Ilya; Wu, Lili; Ryskamp, Daniel A; Bar-Ner, Nira; Natan, Niva; et al.(2016). AF710B, a Novel M1/σ1 Agonist with Therapeutic Efficacy in Animal Models of Alzheimer’s Disease.. Neuro-degenerative diseases, 16(1-2), 95-110. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/0rm238hc
We previously developed orthosteric M1 muscarinic agonists (e.g. AF102B, AF267B and AF292), which act as cognitive enhancers and potential disease modifiers. We now report on a novel compound, AF710B, a highly potent and selective allosteric M1 musca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c808f1fecaeec6a83b471e4875eadfe
https://europepmc.org/articles/PMC4803577/
https://europepmc.org/articles/PMC4803577/