Výsledky vyhledávání - "pharmacology [Dopamine]"

Trial of Deferiprone in Parkinson’s Disease

Autor: Devos, David, Labreuche, Julien, Dušek, Petr, Post, Bart, Bloem, Bastiaan R, Berg, Daniela, Maetzler, Walter, Otto, Markus, Habert, Marie-Odile, Lehericy, Stéphane, Ferreira, Joaquim, Dodel, Richard, Rascol, Olivier, Tranchant, Christine, Eusebio, Alexandre, Thobois, Stéphane, Marques, Ana-Raquel, Meissner, Wassilios G, Ory-Magne, Fabienne, Walter, Uwe, de Bie, Rob M A, Gago, Miguel, Vilas, Dolores, Corvol, Jean-Christophe, Kulisevsky, Jaime, Januario, Cristina, Coelho, Miguel V S, Behnke, Stefanie, Worth, Paul, Seppi, Klaus, Ouk, Thavarak, Potey, Camille, Leclercq, Céline, Viard, Romain, Duhamel, Alain, Kuchcinski, Gregory, Lopes, Renaud, Pruvo, Jean-Pierre, Pigny, Pascal, Garçon, Guillaume, Simonin, Ophélie, Carpentier, Jessica, Rolland, Anne-Sophie, Nyholm, Dag, Scherfler, Christoph, Guyon Delannoy, Pauline, Mangin, Jean-François, Chupin, Marie, Bordet, Régis, Dexter, David T, Fradette, Caroline, Spino, Michael, Tricta, Fernando, Ayton, Scott, Bush, Ashley I, Devedjian, Jean-Christophe, Poewe, Werner, Duce, James A, Cabantchik, Ioav, Defebvre, Luc, Deplanque, Dominique, Moreau, Caroline, Group, FAIRPARK-II Study, Compta, Yaroslau, Pavese, Nicola, Růžička, Evžen

Publikováno v: The New England journal of medicine 387(22), 2045-2055 (2022). doi:10.1056/NEJMoa2209254
The New England Journal of Medicine, 387, 2045-2055
The New England Journal of Medicine, 387, 22, pp. 2045-2055
New England journal of medicine, 387(22), 2045-2055. Massachussetts Medical Society

Contains fulltext : 287484.pdf (Publisher’s version ) (Open Access) BACKGROUND: Iron content is increased in the substantia nigra of persons with Parkinson's disease and may contribute to the pathophysiology of the disorder. Early research suggests

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3511431d06e2ec946902f62c2163ae
https://doi.org/10.1056/nejmoa2209254

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Pharmacological activation of dopamine D4 receptor modulates morphine-induced changes in the expression of GAD65/67 and GABAB receptors in the basal ganglia

Autor: Kirill Shumilov, Antonio Rodríguez-Moreno, José Vicente Negrete-Díaz, José Medina-Luque, Alejandra Valderrama-Carvajal, Alicia Rivera, Gonzalo Flores, M. Ángeles Real

Publikováno v: Neuropharmacology 152, 22-29 (2019). doi:10.1016/j.neuropharm.2019.01.024

Dopamine D4 receptor (D4R) stimulation, in a putative D4R/μ opioid heteroreceptor (MOR) complex, counteracts the molecular, cellular and behavioural actions of morphine which are associated with morphine addiction, without any effect on its analgesi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adc627f11a5d08a30704ce1b23100240
https://doi.org/10.1016/j.neuropharm.2019.01.024

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A new dopaminergic nigro-olfactory projection

Autor: Vincent Ries, Günter U. Höglinger, Andreas Borta, Rainer K.W. Schwarting, Ursula Keber, Wolfgang H. Oertel, Dieter Scheller, Miriam Djufri, Oscar Arias-Carrión, Daniel Alvarez-Fischer, Andrea Windolph

Publikováno v: Acta neuropathologica 130(3), 333-348 (2015). doi:10.1007/s00401-015-1451-y

Parkinson disease (PD) is a neurodegenerative disorder characterized by massive loss of midbrain dopaminergic neurons. Whereas onset of motor impairments reflects a rather advanced stage of the disorder, hyposmia often marks the beginning of the dise

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a42afd330dc60ddbf98fefbacc2ae706
https://doi.org/10.1007/s00401-015-1451-y

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Dopamine elevates and lowers astroglial Ca2+ through distinct pathways depending on local synaptic circuitry

Autor: Jennings, Alistair, Tyurikova, Olga, Bard, Lucie, Zheng, Kaiyu, Semyanov, Alexey, Henneberger, Christian, Rusakov, Dmitri A

Publikováno v: Glia 65(3), 447-459 (2016). doi:10.1002/glia.23103

Whilst astrocytes in culture invariably respond to dopamine with cytosolic Ca2+ rises, the dopamine sensitivity of astroglia in situ and its physiological roles remain unknown. To minimize effects of experimental manipulations on astroglial physiolog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10678::26bb1f2a1ae32c19e8dae3f919388bef
https://pub.dzne.de/record/139131

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Contributions of dopaminergic and non-dopaminergic neurons to VTA-stimulation induced neurovascular responses in brain reward circuits

Autor: Michael T. Lippert, Marta Brocka, Daniel Vincenz, Jürgen Goldschmidt, Thomas Scherf, Dirk Montag, Frank Angenstein, Cornelia Helbing

Publikováno v: NeuroImage 177, 88-97 (2018). doi:10.1016/j.neuroimage.2018.04.059
NeuroImage, 177:88-97

Mapping the activity of the human mesolimbic dopamine system by BOLD-fMRI is a tempting approach to non-invasively study the action of the brain reward system during different experimental conditions. However, the contribution of dopamine release to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204e49f2e2cfaec233156e218ef3515a

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