Alcohol-abuse drug disulfiram targets pediatric glioma via MLL degradation

Autor: S Cantilena, Stefanie Meier, Darren Hargrave, David Michod, John Anderson, Jasper de Boer, Maria Victoria Niklison Chirou, Paolo Salomoni

Publikováno v: Cell Death & Disease
Cell death & disease 12(8), 785 (2021). doi:10.1038/s41419-021-04078-9
Cell Death and Disease, Vol 12, Iss 8, Pp 1-12 (2021)

Pediatric gliomas comprise a broad range of brain tumors derived from glial cells. While high-grade gliomas are often resistant to therapy and associated with a poor outcome, children with low-grade gliomas face a better prognosis. However, the treat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::352d109b5f0dbec2fa754da507bbd703
https://pubmed.ncbi.nlm.nih.gov/34381018