Zobrazeno 1 - 10
of 2 011
pro vyhledávání: '"pharmacokinetics-pharmacodynamics"'
Publikováno v:
BMC Veterinary Research, Vol 20, Iss 1, Pp 1-14 (2024)
Abstract Background The widespread practice of delivering antimicrobials through drinking water to livestock leads to considerable variability in exposure levels among animals, raising concerns regarding disease outbreaks and the emergence of antimic
Externí odkaz:
https://doaj.org/article/ecd31530f450458c962f25c3071d227f
Autor:
Claire Roger
Publikováno v:
Journal of Intensive Medicine, Vol 4, Iss 3, Pp 287-298 (2024)
Effective treatment of sepsis not only demands prompt administration of appropriate antimicrobials but also requires precise dosing to enhance the likelihood of patient survival. Adequate dosing refers to the administration of doses that yield therap
Externí odkaz:
https://doaj.org/article/ef57d3bb7fb34eeda44309601cf25163
Autor:
Youquan Wang, Hongxiang Li, Dongxia Wang, Yuting Li, Yangyang Shen, Yao Fu, Yanhua Li, Meng Gao, Dong Zhang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract This study aimed to explore the changes of pharmacokinetic parameters after meropenem in patients with abdominal septic shock after gastrointestinal perforation, and to simulate the probability of different dosing regimens achieving differen
Externí odkaz:
https://doaj.org/article/06eee52009e34614ae427bd2ba8a09ad
Autor:
Hongjuan Wang, Longfei Zhang
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionActinobacillus pleuropneumoniae (APP) is a serious pathogen that affects the development of livestock breeding. Due to excessive use of antimicrobial drugs, many multidrug-resistant bacteria have emerged and spread, which have threatened
Externí odkaz:
https://doaj.org/article/8f1f8298bc264d7698e37bcc6839166c
Autor:
Susan J. Lewis, Bruce A. Mueller
Publikováno v:
BMC Nephrology, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background The Tablo Hemodialysis System is a new innovative kidney replacement therapy (KRT) providing a range of options for critically ill patients with acute kidney injury. The use of various effluent rate and treatment durations/frequen
Externí odkaz:
https://doaj.org/article/166d2fa55bce49efa64ff26cc7b84f41
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-7 (2024)
Abstract Background With the widespread use of antibiotics, antimicrobial resistance in Neisseria gonorrhoeae is worsening. The objective of this study was to evaluate the efficacy changes of seven antibiotics in the treatment of N. gonorrhoeae by us
Externí odkaz:
https://doaj.org/article/4ecf3ca4230d477a81ab371ad3d517d1
Autor:
Zhiwei Huang, Xingchen Bian, Yi Li, Jiali Hu, Beining Guo, Xinyi Yang, Yi Jin, Shansong Zheng, Xinmei Wang, Cong Gao, Jing Zhang, Xiaojie Wu
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Objective: FL058 is a novel beta-lactamase inhibitor with a broad spectrum of activity and a favorable safety profile. The objective of this study was to evaluate pharmacokinetic/pharmacodynamic (PK/PD) relationships for the combination of FL058 and
Externí odkaz:
https://doaj.org/article/60441e5558104525a9d7e9a014220d30
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1122 (2024)
Remimazolam, widely used for procedural sedation and general anesthesia, is a new ultra short-acting benzodiazepine for intravenous sedation and anesthesia. We aim to characterize the pharmacokinetics/pharmacodynamics (PK/PD) of remimazolam and its m
Externí odkaz:
https://doaj.org/article/67c03e030f81494cb5a2b0528e1b8162
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1124 (2024)
Tafenoquine (TQ) is a new 8-aminoquinoline antimalarial drug developed by the US Army for Plasmodium vivax malaria treatment. Modeling and simulation are essential tools for drug development and improving rationality in pharmacotherapy, and different
Externí odkaz:
https://doaj.org/article/7de46518574948a3b83e668cccbc5134
Autor:
Shinya Chihara, Tomoyuki Ishigo, Satoshi Kazuma, Kana Matsumoto, Kunihiko Morita, Yoshiki Masuda
Publikováno v:
Antibiotics, Vol 13, Iss 8, p 755 (2024)
Aggressive pharmacokinetic (PK)/pharmacodynamic (PD) targets have shown better microbiological eradication rates and a lower propensity to develop resistant strains than conservative targets. We investigated whether meropenem blood levels, including
Externí odkaz:
https://doaj.org/article/aa0ddcbdc4bb492daa7477ccf78dd7ff