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pro vyhledávání: '"pharmacodynamic and efficacy studies"'
Akademický článek
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Autor:
G. K. Lloyd, Ajita V. Singh, Barbara C. M. Potts, Michael A. Palladino, Kenneth C. Anderson, Dharminder Chauhan
Publikováno v:
British Journal of Haematology. 149:550-559
Our previous study showed that the novel proteasome inhibitor NPI-0052 induces apoptosis in multiple myeloma (MM) cells resistant to conventional and bortezomib (Velcade, Takeda, Boston, MA, USA) therapies. In vivo studies using human MM-xenografts d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efe0de85da0fa688a1d5785c67107912
https://doi.org/10.1111/j.1365-2141.2010.08144.x
https://doi.org/10.1111/j.1365-2141.2010.08144.x
Autor:
Singh, Ajita V., Palladino, Michael A., Lloyd, G. Kenneth, Potts, Barbara, Chauhan, Dharminder, Anderson, Kenneth C.
Our previous study showed that the novel proteasome inhibitor NPI-0052 induces apoptosis in multiple myeloma (MM) cells resistant to conventional and bortezomib (Velcade, Takeda, Boston, MA, USA) therapies. In vivo studies using human MM-xenografts d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8cf30496a123cba6e48c28152a5b82ae
https://europepmc.org/articles/PMC4427841/
https://europepmc.org/articles/PMC4427841/
Autor:
Ajita V. Singh, Kenneth C. Anderson, Dharminder Chauhan, Michael A. Palladino, G. Kenneth Lloyd
Publikováno v:
Blood. 112:3665-3665
Background: We recently characterized a novel proteasome inhibitor NPI-0052, a small molecule derived from the fermentation of a marine gram-positive actinomycete Salinispora tropica. NPI-0052 induces apoptosis in multiple myeloma (MM) cells resistan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b4690ad425b0ebb86fd35d1612e895b
https://doi.org/10.1182/blood.v112.11.3665.3665
https://doi.org/10.1182/blood.v112.11.3665.3665
Autor:
Singh, Ajita V., Lloyd, G. Kenneth *, Palladino, Michael A., Chauhan, Dharminder, Anderson, Kenneth C. *
Publikováno v:
In Blood 16 November 2008 112(11):3665-3665
Autor:
S Ryder, Jeffrey I. Everitt, Stephen R. Wedge, V Robinson, Paul Workman, Martin J. Glennie, D.J. Chaplin, V Navaratnam, Gillian M. Tozer, D A H Farningham, Lloyd R. Kelland, John A. Double, Allan Balmain, G Bruder, Suzanne A. Eccles, Frances R. Balkwill, Susan A. Watson, Ian J. Stratford, Eric O. Aboagye
Publikováno v:
British Journal of Cancer
Animal experiments remain essential to understand the fundamental mechanisms underpinning malignancy and to discover improved methods to prevent, diagnose and treat cancer. Excellent standards of animal care are fully consistent with the conduct of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f529462ba29f74e91ce38826531f7b5
https://doi.org/10.1038/sj.bjc.6605642
https://doi.org/10.1038/sj.bjc.6605642
Autor:
Kusaczuk, Magdalena1 (AUTHOR) mkusaczuk@wp.pl, Tyszka, Natalia1 (AUTHOR), Krętowski, Rafał1 (AUTHOR), Cechowska-Pasko, Marzanna1 (AUTHOR) mkusaczuk@wp.pl
Publikováno v:
Pharmaceuticals (14248247). Aug2024, Vol. 17 Issue 8, p1089. 15p.
Autor:
Workman, P, Aboagye, EO, Balkwill, F, Balmain, A, Bruder, G, Chaplin, DJ, Double, JA, Everitt, J, Farningham, DAH, Glennie, MJ, Kelland, LR, Robinson, V, Stratford, IJ, Tozer, GM, Watson, S, Wedge, SR, Eccles, SA, Committee of the National Cancer Research Institute
Publikováno v:
British journal of cancer, vol 102, iss 11
Animal experiments remain essential to understand the fundamental mechanisms underpinning malignancy and to discover improved methods to prevent, diagnose and treat cancer. Excellent standards of animal care are fully consistent with the conduct of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1f60c0f813ca8ef5379712ce53259ab5
https://escholarship.org/uc/item/748691d2
https://escholarship.org/uc/item/748691d2
Autor:
Maulvi, Furqan A., Patel, Ashmi R., Shetty, Kiran H., Desai, Ditixa T., Shah, Dinesh O., Willcox, Mark D. P.
Publikováno v:
Drug Delivery & Translational Research; Nov2024, Vol. 14 Issue 11, p3212-3224, 13p
Autor:
Abulwerdi, Gelareh A.1 (AUTHOR) gelareh.abulwerdi@fda.hhs.gov, Ramamoorthy, Anuradha1 (AUTHOR), Bashaw, Edward1 (AUTHOR), Burckart, Gilbert J.1 (AUTHOR), Madabushi, Rajanikanth1 (AUTHOR), Fletcher, Elimika Pfuma1 (AUTHOR)
Publikováno v:
CTS: Clinical & Translational Science. Oct2023, Vol. 16 Issue 10, p2046-2057. 12p.