Zobrazeno 1 - 10
of 325
pro vyhledávání: '"pharmaceutical proteins"'
Publikováno v:
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-17 (2021)
Abstract Monoclonal antibodies, antibody fragments and fusion proteins derived thereof have revolutionized the practice of medicine. Major challenges faced by the biopharmaceutical industry are however high production costs, long processing times and
Externí odkaz:
https://doaj.org/article/a774b0c4890f4a01b4bd04da0adef376
Autor:
Mohsen Akbarian, Shu-Hui Chen
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2533 (2022)
Maintaining the structure of protein and peptide drugs has become one of the most important goals of scientists in recent decades. Cold and thermal denaturation conditions, lyophilization and freeze drying, different pH conditions, concentrations, io
Externí odkaz:
https://doaj.org/article/547186994d644917a87187fc9c275d70
Autor:
Jaakko Itkonen, Leo Ghemtio, Daniela Pellegrino, Pia J. Jokela (née Heinonen), Henri Xhaard, Marco G. Casteleijn
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1639 (2022)
Pharmaceutical proteins, compared to small molecular weight drugs, are relatively fragile molecules, thus necessitating monitoring protein unfolding and aggregation during production and post-marketing. Currently, many analytical techniques take offl
Externí odkaz:
https://doaj.org/article/927cd2094a154036a17e0b177537a3c5
Autor:
Azadeh Niknejad
Publikováno v:
یافتههای نوین در علوم زیستی, Vol 5, Iss 3, Pp 262-273 (2018)
Molecular farming technology offers a unique advantage that almost any protein can be produced economically and safely under very controlled conditions. Besides traditional production systems, such as bacteria, yeasts, insects and mammal cell lines,
Externí odkaz:
https://doaj.org/article/5d9fffc190f64874bf994d9d7d0f8abf
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Autor:
Ingrid Ramm, Adrian Sanchez-Fernandez, Jaeyeong Choi, Christian Lang, Jonas Fransson, Herje Schagerlöf, Marie Wahlgren, Lars Nilsson
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1853 (2021)
The addition of glycerol to protein solutions is often used to hinder the aggregation and denaturation of proteins. However, it is not a generalised practice against chemical degradation reactions. The chemical degradation of proteins, such as deamid
Externí odkaz:
https://doaj.org/article/9f1544ffd84b4b91b9480d507d08173d
Akademický článek
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Publikováno v:
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-17 (2021)
Wang, Y, Li, X, Chen, X, Nielsen, J, Petranovic, D & Siewers, V 2021, ' Expression of antibody fragments in Saccharomyces cerevisiae strains evolved for enhanced protein secretion ', Microbial Cell Factories, vol. 20, 134 . https://doi.org/10.1186/s12934-021-01624-0
Microbial Cell Factories
Wang, Y, Li, X, Chen, X, Nielsen, J, Petranovic, D & Siewers, V 2021, ' Expression of antibody fragments in Saccharomyces cerevisiae strains evolved for enhanced protein secretion ', Microbial Cell Factories, vol. 20, 134 . https://doi.org/10.1186/s12934-021-01624-0
Microbial Cell Factories
Monoclonal antibodies, antibody fragments and fusion proteins derived thereof have revolutionized the practice of medicine. Major challenges faced by the biopharmaceutical industry are however high production costs, long processing times and low prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0687c1504ece369a81ef5125b2ff9ecd
https://doaj.org/article/a774b0c4890f4a01b4bd04da0adef376
https://doaj.org/article/a774b0c4890f4a01b4bd04da0adef376
