Zobrazeno 1 - 10
of 25 206
pro vyhledávání: '"phage-display"'
Autor:
Soobin Han, Ji Hong Kim, Vivek Kumar Gupta, Ju Eun Bae, Chae Hwan Cho, Hanseung Kim, Yonghyeon Park, Mi‐Hwa Oh, Jong Pil Park Professor, Yun Suk Huh
Publikováno v:
Food Frontiers, Vol 5, Iss 6, Pp 2591-2604 (2024)
Abstract The globalization of food distribution has made it necessary to ensure the delivery of fresh food to the consumers. Protein‐rich foods produce a significant amount of tyramine when spoiled. Therefore, it was envisaged to develop localized
Externí odkaz:
https://doaj.org/article/7facf9a096ae4f22b7d4db500d4d6d3e
Autor:
Sharareh Mohammad Hasani, Mahdi Behdani, Zohreh Amirkhani, Ilnaz Rahimmanesh, Mahsa Esmaeilifallah, Erfan Zaker, Parvaneh Nikpour, Mahmood Fadaie, Elham Ghafouri, Shamsi Naderi, Hossein Khanahmad
Publikováno v:
Research in Pharmaceutical Sciences, Vol 19, Iss 5, Pp 573-590 (2024)
Background and purpose: The global emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has prompted widespread concern. Bacteriophages have recently gained attention as a cost-effective and stable alternative for vaccine dev
Externí odkaz:
https://doaj.org/article/7412bf70a95946cbbe1e94c4e75346be
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Influenza continues to be one of the top public health problems since it creates annual epidemics and can start a worldwide pandemic. The virus’s rapid evolution allows the virus to evade the host defense, and then seasonal vaccines need t
Externí odkaz:
https://doaj.org/article/e5ef4b3df0214805bf501989900c1135
Autor:
Yu Fan, Ruibing Feng, Xinya Zhang, Zhen-Liang Wang, Feng Xiong, Shuihua Zhang, Zhang-Feng Zhong, Hua Yu, Qing-Wen Zhang, Zhang Zhang, Yitao Wang, Guodong Li
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 8, Pp 3362-3384 (2024)
Drug discovery is a sophisticated process that incorporates scientific innovations and cutting-edge technologies. Compared to traditional bioactivity-based screening methods, encoding and display technologies for combinatorial libraries have recently
Externí odkaz:
https://doaj.org/article/8c51e2672b6e4c08aee0596430c903da
Autor:
Johanna Kliche, Leandro Simonetti, Izabella Krystkowiak, Hanna Kuss, Marcel Diallo, Emma Rask, Jakob Nilsson, Norman E Davey, Ylva Ivarsson
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 9, Pp 1025-1048 (2024)
Abstract Whole genome and exome sequencing are reporting on hundreds of thousands of missense mutations. Taking a pan-disease approach, we explored how mutations in intrinsically disordered regions (IDRs) break or generate protein interactions mediat
Externí odkaz:
https://doaj.org/article/0bbc2585d8e5430193b425c67f6f3b23
Autor:
Yulia S. Massino, Yulia N. Tarakanova, Olga L. Segal, Anastasia A. Pechelyulko, Dinora A. Yakovleva, Maria V. Lichutina, Dmitriy A. Dmitriev, Alexander D. Dmitriev
Publikováno v:
Журнал микробиологии, эпидемиологии и иммунобиологии, Vol 101, Iss 3, Pp 412-427 (2024)
Monoclonal antibodies are widely used in all fields of biology and medicine. The emergence and development of the technology for their production revolutionized immunology and allowed the creation of not only new diagnostic methods, but also many eff
Externí odkaz:
https://doaj.org/article/17dd52db90804d1e8d601fdc1ddbf7d5
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Using conventional immunoglobulin G (IgG) molecules as therapeutic agents presents several well-known disadvantages owing to their large size and structural complexity, negatively impacting development and production efficiency. Single-domai
Externí odkaz:
https://doaj.org/article/d86067ade20f4a04a6a1aa6bb6b3d357
Autor:
Qingyu Ren, Yu Sheng, Ling Sun, Feijian Zheng, Chengwu Hu, Jianqing Chen, Zhengbing Lyu, Chen Yuan, Xiaofeng Jiang
Publikováno v:
Frontiers in Marine Science, Vol 11 (2024)
IntroductionB-cell lymphoma, a malignant proliferative disease originating from lymphoid tissue, poses a grave threat to human health. CD20 has emerged as a promising target for lymphoma treatment. However, due to the significant heterogeneity of B-c
Externí odkaz:
https://doaj.org/article/09108f0f62da46c7988618e93cb94c46
Autor:
Michele Pitaro, Giovanni Antonini, Alessandro Arcovito, Francesco Buccisano, Alfredo De Lauro, Maria Irno Consalvo, Valentina Gallo, Noah Giacon, Giuseppe Felice Mangiatordi, Maddalena Pacelli, Maria Teresa Pitaro, Fabio Polticelli, Matteo Sorrenti, Adriano Venditti
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundMature T-cell neoplasms arise from the neoplastic transformation of a single T lymphocyte, and all cells in a neoplastic clone share the same V segment in the beta chain of the T-cell receptor (TCR). These segments may represent an innovati
Externí odkaz:
https://doaj.org/article/9b22bb8d9430438db1ba358cc30ff6c2
Autor:
Melissa R. Soto, Mae M. Lewis, Jasmim Leal, Yuting Pan, Rashmi P. Mohanty, Arian Veyssi, Esther Y. Maier, Brittany J. Heiser, Debadyuti Ghosh
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 4, Pp 102375- (2024)
For cystic fibrosis patients, a lung-targeted gene therapy would significantly alleviate pulmonary complications associated with morbidity and mortality. However, mucus in the airways and cell entry pose huge delivery barriers for local gene therapy.
Externí odkaz:
https://doaj.org/article/e8f77c73d20b47b7862c329c25cf9246