Zobrazeno 1 - 10
of 25 191
pro vyhledávání: '"phage display."'
Autor:
Soobin Han, Ji Hong Kim, Vivek Kumar Gupta, Ju Eun Bae, Chae Hwan Cho, Hanseung Kim, Yonghyeon Park, Mi‐Hwa Oh, Jong Pil Park Professor, Yun Suk Huh
Publikováno v:
Food Frontiers, Vol 5, Iss 6, Pp 2591-2604 (2024)
Abstract The globalization of food distribution has made it necessary to ensure the delivery of fresh food to the consumers. Protein‐rich foods produce a significant amount of tyramine when spoiled. Therefore, it was envisaged to develop localized
Externí odkaz:
https://doaj.org/article/7facf9a096ae4f22b7d4db500d4d6d3e
Autor:
Sharareh Mohammad Hasani, Mahdi Behdani, Zohreh Amirkhani, Ilnaz Rahimmanesh, Mahsa Esmaeilifallah, Erfan Zaker, Parvaneh Nikpour, Mahmood Fadaie, Elham Ghafouri, Shamsi Naderi, Hossein Khanahmad
Publikováno v:
Research in Pharmaceutical Sciences, Vol 19, Iss 5, Pp 573-590 (2024)
Background and purpose: The global emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has prompted widespread concern. Bacteriophages have recently gained attention as a cost-effective and stable alternative for vaccine dev
Externí odkaz:
https://doaj.org/article/7412bf70a95946cbbe1e94c4e75346be
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Influenza continues to be one of the top public health problems since it creates annual epidemics and can start a worldwide pandemic. The virus’s rapid evolution allows the virus to evade the host defense, and then seasonal vaccines need t
Externí odkaz:
https://doaj.org/article/e5ef4b3df0214805bf501989900c1135
Autor:
Yu Fan, Ruibing Feng, Xinya Zhang, Zhen-Liang Wang, Feng Xiong, Shuihua Zhang, Zhang-Feng Zhong, Hua Yu, Qing-Wen Zhang, Zhang Zhang, Yitao Wang, Guodong Li
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 8, Pp 3362-3384 (2024)
Drug discovery is a sophisticated process that incorporates scientific innovations and cutting-edge technologies. Compared to traditional bioactivity-based screening methods, encoding and display technologies for combinatorial libraries have recently
Externí odkaz:
https://doaj.org/article/8c51e2672b6e4c08aee0596430c903da
Autor:
Johanna Kliche, Leandro Simonetti, Izabella Krystkowiak, Hanna Kuss, Marcel Diallo, Emma Rask, Jakob Nilsson, Norman E Davey, Ylva Ivarsson
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 9, Pp 1025-1048 (2024)
Abstract Whole genome and exome sequencing are reporting on hundreds of thousands of missense mutations. Taking a pan-disease approach, we explored how mutations in intrinsically disordered regions (IDRs) break or generate protein interactions mediat
Externí odkaz:
https://doaj.org/article/0bbc2585d8e5430193b425c67f6f3b23
Autor:
Yulia S. Massino, Yulia N. Tarakanova, Olga L. Segal, Anastasia A. Pechelyulko, Dinora A. Yakovleva, Maria V. Lichutina, Dmitriy A. Dmitriev, Alexander D. Dmitriev
Publikováno v:
Журнал микробиологии, эпидемиологии и иммунобиологии, Vol 101, Iss 3, Pp 412-427 (2024)
Monoclonal antibodies are widely used in all fields of biology and medicine. The emergence and development of the technology for their production revolutionized immunology and allowed the creation of not only new diagnostic methods, but also many eff
Externí odkaz:
https://doaj.org/article/17dd52db90804d1e8d601fdc1ddbf7d5
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Using conventional immunoglobulin G (IgG) molecules as therapeutic agents presents several well-known disadvantages owing to their large size and structural complexity, negatively impacting development and production efficiency. Single-domai
Externí odkaz:
https://doaj.org/article/d86067ade20f4a04a6a1aa6bb6b3d357
Autor:
Melissa R. Soto, Mae M. Lewis, Jasmim Leal, Yuting Pan, Rashmi P. Mohanty, Arian Veyssi, Esther Y. Maier, Brittany J. Heiser, Debadyuti Ghosh
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 4, Pp 102375- (2024)
For cystic fibrosis patients, a lung-targeted gene therapy would significantly alleviate pulmonary complications associated with morbidity and mortality. However, mucus in the airways and cell entry pose huge delivery barriers for local gene therapy.
Externí odkaz:
https://doaj.org/article/e8f77c73d20b47b7862c329c25cf9246
Autor:
Marcelo Jacobs-Lorena, Sung-Jae Cha
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
Malaria is among the deadliest infectious diseases. Over 200 million annual clinical malaria cases are reported and more than half a million people, mostly children, die every year. The most advanced RTS,S/AS01 vaccine based on the P. falciparum circ
Externí odkaz:
https://doaj.org/article/e30304767ca24b1eb265a1f99fc7412a
Autor:
Marianne Bachmann Salvy, Luca Santuari, Emanuel Schmid-Siegert, Nikolaos Lykoskoufis, Ioannis Xenarios, Bulak Arpat
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
Antibodies have emerged as the leading class of biotherapeutics, yet traditional screening methods face significant time and resource challenges in identifying lead candidates. Integrating high-throughput sequencing with computational approaches mark
Externí odkaz:
https://doaj.org/article/f85acb18d6bb4dca8286f8f0fd6b6991