Zobrazeno 1 - 10
of 222
pro vyhledávání: '"peter Schlenke"'
Publikováno v:
Pharmaceutics, Vol 16, Iss 10, p 1317 (2024)
Background: There is a narrow therapeutic window for immunosuppression using calcineurin inhibitors. Drug trough levels do not reflect immunosuppression and should be replaced by pharmacodynamic monitoring. This prospective cohort study was designed
Externí odkaz:
https://doaj.org/article/83c63cf9bbf24963aeb117f7e3a78f56
Publikováno v:
Stem Cell Research, Vol 64, Iss , Pp 102910- (2022)
We performed reprogramming of human erythroblasts derived from CD34+ hematopoietic stem / progenitor cells of a healthy donor. CD34+ cells were differentiated in-vitro into a pure population of CD36+ erythroblasts and nucleofected with four episomal
Externí odkaz:
https://doaj.org/article/1d520636f1cc449b85e5eb1a3cc9b609
Autor:
Claudia Bernecker, Maria Lima, Tatjana Kolesnik, Annika Lampl, Catalin Ciubotaru, Riccardo Leita, Dagmar Kolb, Eleonore Fröhlich, Peter Schlenke, Gerhard A. Holzapfel, Isabel Dorn, Dan Cojoc
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Modern medicine increases the demand for safe blood products. Ex vivo cultured red blood cells (cRBC) are eagerly awaited as a standardized, safe source of RBC. Established culture models still lack the terminal cytoskeletal remodeling from reticuloc
Externí odkaz:
https://doaj.org/article/6d259a3685024f7184fef1f6c2fbaf4e
Autor:
Stefan Hatzl, Florian Posch, Nazanin Sareban, Martin Stradner, Konrad Rosskopf, Alexander C. Reisinger, Philipp Eller, Michael Schörghuber, Wolfgang Toller, Zdenka Sloup, Florian Prüller, Katharina Gütl, Stefan Pilz, Alexander R. Rosenkranz, Hildegard T. Greinix, Robert Krause, Peter Schlenke, Gernot Schilcher
Publikováno v:
Annals of Intensive Care, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Background This study aimed to quantify the potential survival benefit of convalescent plasma therapy (CVP) in critically ill patients with acute respiratory failure related to coronavirus disease-2019 (COVID-19). Methods This is a single-ce
Externí odkaz:
https://doaj.org/article/a98ae351f6124254a83c929fde57044f
Autor:
Eduard Schulz, Isabel Hodl, Patrick Forstner, Stefan Hatzl, Nazanin Sareban, Martina Moritz, Johannes Fessler, Barbara Dreo, Barbara Uhl, Claudia Url, Andrea J. Grisold, Michael Khalil, Barbara Kleinhappl, Christian Enzinger, Martin H. Stradner, Hildegard T. Greinix, Peter Schlenke, Ivo Steinmetz
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Immunocompromised patients are considered high-risk and prioritized for vaccination against COVID-19. We aimed to analyze B-cell subsets in these patients to identify potential predictors of humoral vaccination response. Patients (n=120) suffering fr
Externí odkaz:
https://doaj.org/article/d95143a5e2e14deebe59299291a8d7cc
Autor:
Claudia Bernecker, Eva Maria Matzhold, Dagmar Kolb, Afrim Avdili, Lisa Rohrhofer, Annika Lampl, Martin Trötzmüller, Heike Singer, Johannes Oldenburg, Peter Schlenke, Isabel Dorn
Publikováno v:
Cells, Vol 11, Iss 16, p 2473 (2022)
Cultured red blood cells from human induced pluripotent stem cells (cRBC_iPSCs) are a promising source for future concepts in transfusion medicine. Before cRBC_iPSCs will have entrance into clinical or laboratory use, their functional properties and
Externí odkaz:
https://doaj.org/article/f1d6cb1f3e774da2b324e5b5155c9897
Autor:
Katarina Kovacic Krizanic, Florian Prüller, Konrad Rosskopf, Jean-Marc Payrat, Silke Andresen, Peter Schlenke
Publikováno v:
Pathogens, Vol 11, Iss 7, p 805 (2022)
Cryoprecipitate is a plasma-derived blood product, enriched for fibrinogen, factor VIII, factor XIII, and von Willebrand factor. Due to infectious risk, the use of cryoprecipitate in Central Europe diminished over the last decades. However, after the
Externí odkaz:
https://doaj.org/article/64157c5f4f8543a1ae016beb05505164
Autor:
Sabine Lichtenegger, Julia Stiehler, Sabine Saiger, Andrea Zauner, Barbara Kleinhappl, Claudia Bernecker, Peter Schlenke, Gabriel E Wagner, Kathrin Krause, Magdalena Gastager, Ivo Steinmetz
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 11, p e0008840 (2020)
Most of the current knowledge on Burkholderia pseudomallei-induced inflammasome activation and cell death in macrophages is derived from murine systems. Little is known about the involved bacterial structures and mechanisms in primary human macrophag
Externí odkaz:
https://doaj.org/article/b6847a495f534362b08508c603985871
Autor:
Claudia Bernecker, Harald Köfeler, Georg Pabst, Martin Trötzmüller, Dagmar Kolb, Karl Strohmayer, Slave Trajanoski, Gerhard A. Holzapfel, Peter Schlenke, Isabel Dorn
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Ex vivo generation of red blood cells (cRBCs) is an attractive tool in basic research and for replacing blood components donated by volunteers. As a prerequisite for the survival of cRBCs during storage as well as in the circulation, the quality of t
Externí odkaz:
https://doaj.org/article/78cd14b974f747538647a84909a60d77
Autor:
Silke Schrom, Thomas Hebesberger, Stefanie Angela Wallner, Ines Anders, Erika Richtig, Waltraud Brandl, Birgit Hirschmugl, Mariangela Garofalo, Claudia Bernecker, Peter Schlenke, Karl Kashofer, Christian Wadsack, Ariane Aigelsreiter, Ellen Heitzer, Sabrina Riedl, Dagmar Zweytick, Nadine Kretschmer, Georg Richtig, Beate Rinner
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11318 (2021)
Melanomas are aggressive tumors with a high metastatic potential and an increasing incidence rate. They are known for their heterogeneity and propensity to easily develop therapy-resistance. Nowadays they are one of the most common cancers diagnosed
Externí odkaz:
https://doaj.org/article/c86b37e968a74524acd04b21308ff46f