Zobrazeno 1 - 10
of 3 564
pro vyhledávání: '"personalized treatment"'
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Objective Colorectal cancer (CRC) is characterized by high incidence and mortality rates worldwide. In this study, we present a novel aging-related gene-based risk scoring system (Aging score) as a predictive tool for CRC prognosis. Method:
Externí odkaz:
https://doaj.org/article/ae2b2b22d2eb46be83f362b307592321
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Nasopharyngeal carcinoma (NPC) arises from the mucosal epithelium of the nasopharynx and is frequently located in the pharyngeal crypts. This is a highly aggressive malignant tumor that frequently leads to distant metastases in many cases an
Externí odkaz:
https://doaj.org/article/eb194e0384514dc5bc14de01a91393d7
Publikováno v:
BMC Immunology, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background Glioblastoma is characterized by high aggressiveness, frequent recurrence, and poor prognosis. Histone acetylation-associated genes have been implicated in its occurrence and development, yet their predictive ability in glioblasto
Externí odkaz:
https://doaj.org/article/7880f7cfe1a1411d9b514a5a82d50209
Publikováno v:
Surgeries, Vol 5, Iss 3, Pp 499-516 (2024)
The challenges inherent in spinal oncology are multi-dimensional, stemming from the complex anatomy of the spine, the high risk of neurological complications, and the indispensability of personalized treatment plans. These challenges are further comp
Externí odkaz:
https://doaj.org/article/e7e85ee8742d43589c7c6f481ac9b9f1
Publikováno v:
Dermatology and Therapy, Vol 14, Iss 7, Pp 1729-1738 (2024)
Abstract Atopic dermatitis (AD) is a chronic inflammatory skin condition. The pathogenesis involves genetic, environmental, and immunological factors as well as a barrier dysfunction of the epidermis. Biomarkers may play a significant role in diagnos
Externí odkaz:
https://doaj.org/article/7040b67fcaff4677889b0bfe2d400306
Autor:
Oleg V. Drobotun, Nikolai N. Kolotilov, Volodymyr F. Konovalenko, Sergii V. Konovalenko, Nikolai N. Ternovyy
Publikováno v:
Клінічна та профілактична медицина, Iss 3, Pp 132-141 (2024)
Introduction. The article is devoted to the current problem of modern oncology – increasing the treatment effectiveness of cancer patients with comorbidities. Comorbidity is accompanied by higher rates of mortality, disability, side effects of trea
Externí odkaz:
https://doaj.org/article/c78eb9d5c1634cfcb9f4ca70f3ac49e8
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Background Cancer stem cells (CSCs) and long non-coding RNAs (lncRNAs) are known to play a crucial role in the growth, migration, recurrence, and drug resistance of tumor cells, particularly in triple-negative breast cancer (TNBC). This stud
Externí odkaz:
https://doaj.org/article/8d76208372644d98ae464eaf46ffa8ad
Autor:
Ravneet Chhabra
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Precision medicine is revolutionizing the world in combating different disease modalities, including cancer. The concept of personalized treatments is not new, but modeling it into a reality has faced various limitations. The last decade has seen sig
Externí odkaz:
https://doaj.org/article/248f2ff180244f26b0bdf28d5a381f72
Autor:
U. Okazaki, I. Nakayama, N. Sakamoto, T. Kuwata, A. Kawazoe, M. Yoshida, M. Yura, Y. Matsubara, A. Jubashi, S. Sato, S. Ushiyama, Y. Miyashita, A. Kobayashi, T. Hashimoto, S. Mishima, D. Kotani, Y. Nakamura, Y. Kuboki, H. Bando, T. Kojima, T. Yoshino, T. Kinoshita, K. Shitara
Publikováno v:
ESMO Gastrointestinal Oncology, Vol 5, Iss , Pp 100086- (2024)
Background: Evaluating multiple biomarkers including human epidermal growth factor receptor 2 (HER2), mismatch repair (MMR) status, programed death-ligand 1 (PD-L1), and claudin 18.2 (CLDN18.2) is essential for selecting appropriate first-line therap
Externí odkaz:
https://doaj.org/article/e80fd40b8c964d00924be1440d8c3a14
Autor:
Huifang Guan, Shuang Zhao, Jiarui Li, Ying Wang, Ping Niu, Yuxin Zhang, Yanjiao Zhang, Xinyi Fang, Runyu Miao, Jiaxing Tian
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
This review examines the complexities of Type 2 Diabetes Mellitus (T2DM), focusing on the critical role of integrating omics technologies with traditional experimental methods. It underscores the advancements in understanding the genetic diversity of
Externí odkaz:
https://doaj.org/article/1f5e400ae1734c7588737beaf224b7ec