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PERP May Affect the Prognosis of Lung Adenocarcinoma by Inhibiting Apoptosis

Autor: Liu Z, Han S, Luo Y, Zhao Z, Ni L, Chai L, Tang H

Publikováno v: Cancer Management and Research, Vol Volume 16, Pp 199-214 (2024)

Zhongxiang Liu,1,* Shuhua Han,2,* Yuhong Luo,3,* Zhangyan Zhao,4 Lingyu Ni,5 Linlin Chai,6 Haicheng Tang4 1Department of Pulmonary and Critical Care Medicine, the Yancheng Clinical College of Xuzhou Medical University, The First People’

Externí odkaz: https://doaj.org/article/9dc2353033f344f3b229628fa440edde

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Akademický článek

Illustrating Important Effects of Second-Order Sensitivities on Response Uncertainties in Reactor Physics

Autor: Dan G. Cacuci

Publikováno v: Journal of Nuclear Engineering, Vol 2, Iss 2, Pp 114-123 (2021)

This paper illustrates the relative importance of the largest first- and second-order sensitivities of the leakage response of an OECD/NEA reactor physics benchmark (a polyethylene-reflected plutonium sphere) to the benchmark’s underlying total cro

Externí odkaz: https://doaj.org/article/e1166d29ebc44676a2b211582a9b3cbb

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Akademický článek

Insulin receptor substrate 1 gene expression is strongly up-regulated by HSPB8 silencing in U87 glioma cells

Autor: Hnatiuk Oksana S., Tsymbal Dariia O., Minchenko Dmytro O., Khita Olena O., Viletska Yulia M., Rundytska Olha V., Kozynkevych Halyna E., Maslak Hanna S., Minchenko Oleksandr H.

Publikováno v: Endocrine Regulations, Vol 54, Iss 4, Pp 231-243 (2020)

Objective. The aim of the present investigation was to study the expression of genes encoding IRS1 (insulin receptor substrate 1) and some other functionally active proteins in U87 glioma cells under silencing of polyfunctional chaperone HSPB8 for ev

Externí odkaz: https://doaj.org/article/b45330ce0084424193b26340eb8116c3

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Upregulation of METTL14 mediates the elevation of PERP mRNA N6 adenosine methylation promoting the growth and metastasis of pancreatic cancer

Autor: Min Wang, Jun Liu, Yan Zhao, Ruizhi He, Xiaodong Xu, Xingjun Guo, Xu Li, Simiao Xu, Ji Miao, Jianpin Guo, Hang Zhang, Jun Gong, Feng Zhu, Rui Tian, Chengjian Shi, Feng Peng, Yechen Feng, Shuo Yu, Yu Xie, Jianxin Jiang, Min Li, Wenyi Wei, Chuan He, Renyi Qin

Publikováno v: Molecular Cancer, Vol 19, Iss 1, Pp 1-15 (2020)

Abstract Background Pancreatic cancer is one of the most lethal human cancers. N 6-methyladenosine (m6A), a common eukaryotic mRNA modification, plays critical roles in both physiological and pathological processes. However, its role in pancreatic ca

Externí odkaz: https://doaj.org/article/7b43f90622754d36a7c0300e57b2b7ae

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Akademický článek

IKKα mediates UVB-induced cell apoptosis by regulating p53 pathway activation

Autor: Hongli Wang, Min Zhang, Xiuduan Xu, Shaojun Hou, Zhihui Liu, Xuejiao Chen, Chongchong Zhang, Huan Xu, Lin Wu, Kun Liu, Lun Song

Publikováno v: Ecotoxicology and Environmental Safety, Vol 227, Iss , Pp 112892- (2021)

Exposure to ultraviolet B (UVB) has been demonstrated to induce DNA damage as well as angiogenesis-related photo-damages, which are implicated in a variety of medical problems, including sunburn, photo-aging and skin cancers. However, the molecular m

Externí odkaz: https://doaj.org/article/2e47407df2da434e9f7f672e45cf7257

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