Zobrazeno 1 - 10
of 423
pro vyhledávání: '"permeability assay"'
Autor:
Pitaksit Supjaroen, Wisanu Niamsi, Pannawich Thirabowonkitphithan, Parichut Thummarati, Wanida Laiwattanapaisal
Publikováno v:
HardwareX, Vol 20, Iss , Pp e00603- (2024)
The permeability-based assay is commonly used to assess intestinal barrier function, and it relies on using a transwell insert as an essential compartment. The device consists of a semipermeable membrane that is attached at the bottom of the insert a
Externí odkaz:
https://doaj.org/article/e32a9b18e9c94f6daaf4633515db1b92
Autor:
András Dohárszky, Erika Mária Vági, Árpád Könczöl, Alexandra Simon, Erzsébet Várnagy, Miras Muratov, Kristóf István Steiger, Bianka Várnai, Szabolcs Béni, Eszter Riethmüller, Ida Fejős
Publikováno v:
Molecules, Vol 29, Iss 22, p 5302 (2024)
Mitragynine is an “atypic opioid” analgesic with an alternative mechanism of action and a favorable side-effect profile. Our aim was to optimize the alkaloid extraction procedure from kratom leaves and to determine and isolate the most relevant c
Externí odkaz:
https://doaj.org/article/7db4b8936f3c42b7856ddcae2c74d4cc
Autor:
Rintaro Kato, Wenyu Zeng, Vishal B. Siramshetty, Jordan Williams, Md Kabir, Natalie Hagen, Elias C. Padilha, Amy Q. Wang, Ewy A. Mathé, Xin Xu, Pranav Shah
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Efficiently circumventing the blood-brain barrier (BBB) poses a major hurdle in the development of drugs that target the central nervous system. Although there are several methods to determine BBB permeability of small molecules, the Parallel Artific
Externí odkaz:
https://doaj.org/article/f2af9b80c1964c48b71ae481314f0507
Autor:
Kevin Tsai, Caixia Ma, Xiao Han, Joannie Allaire, Genelle R. Healey, Shauna M. Crowley, Hongbing Yu, Kevan Jacobson, Lijun Xia, John J. Priatel, Bruce A. Vallance
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 2, Pp 425-438 (2023)
Background & Aims: Increased intestinal permeability is seen in a variety of inflammatory conditions such as enteric infections and inflammatory bowel disease. Because barrier function can provide a key biomarker of disease severity, it often is assa
Externí odkaz:
https://doaj.org/article/e200241212c84c828e2aef45303564ca
Autor:
Riley D. Kirk, Toyosi Akanji, Huifang Li, Jie Shen, Saleh Allababidi, Navindra P. Seeram, Matthew J. Bertin, Hang Ma
Publikováno v:
Medical Cannabis and Cannabinoids, Vol 5, Iss 1, Pp 129-137 (2022)
Introduction: Cannabinoids including cannabidiol (CBD) have attracted enormous interest as bioactive ingredients for various dermatological and/or cosmeceutical uses. However, topical applications of cannabinoids might be limited without a fundamenta
Externí odkaz:
https://doaj.org/article/940b5f9c6254466eb9967112f789d561
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Environment International, Vol 170, Iss , Pp 107589- (2022)
Parallel Artificial Membrane Permeability Assay (PAMPA) is an in vitro laboratory method for screening the transmembrane permeability of chemicals. Stemming from medicinal chemistry, PAMPA has the potential for use in the cost-effective high-throughp
Externí odkaz:
https://doaj.org/article/ee2b040d608342bdb74f074cbd11a56d
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Domenico Ventrella, Roberta Salaroli, Alberto Elmi, Giacomo Carnevali, Monica Forni, Fabio Baldi, Maria Laura Bacci
Publikováno v:
Veterinary World, Vol 13, Iss 12, Pp 2728-2735 (2020)
Aim: The aim of the study was to set up a porcine ex vivo model of acid-induced damage and to evaluate its performance by means of multichannel intraluminal impedance and pH (MII-pH) live recording, histology, and Evans blue (EB) permeability assay.
Externí odkaz:
https://doaj.org/article/c3daf91e54ff422ab77114205aa0341f