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A Diazirine‐Modified Membrane Lipid to Study Peptide/Lipid Interactions – Chances and Challenges

Autor: Simon Drescher, Kai Gruhle, Vasil M. Garamus, Andrea Sinz, Christian Schwieger, Julia Dorner, Annette Meister, Hauke Lilie, Christian Ihling, Patricia Korn, Daniel Ramsbeck

Publikováno v: Dorner, J.; Korn, P.; Gruhle, K.; Ramsbeck, D.; Garamus, V.; Lilie, H.; Meister, A.; Schwieger, C.; Ihling, C.; Sinz, A.; Drescher, S.: A Diazirine-Modified Membrane Lipid to Study Peptide/Lipid Interactions – Chances and Challenges. In: Chemistry-A European Journal. Vol. 27 (2021) 59, 14586-14593. (DOI: /10.1002/chem.202102048)
Chemistry (Weinheim an Der Bergstrasse, Germany)

Although incorporation of photo‐activatable lipids into membranes potentially opens up novel avenues for investigating interactions with proteins, the question of whether diazirine‐modified lipids are suitable for such studies, remains under deba

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361ba8379c6323d4b71ac206abf437e7
https://doi.org/10.1002/chem.202102048

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Biophysical Investigations Elucidating the Mechanisms of Action of Antimicrobial Peptides and Their Synergism

Autor: Arnaud Marquette, Burkhard Bechinger

Publikováno v: Biomolecules, Vol 8, Iss 2, p 18 (2018)

Biophysical and structural investigations are presented with a focus on the membrane lipid interactions of cationic linear antibiotic peptides such as magainin, PGLa, LL37, and melittin. Observations made with these peptides are distinct as seen from

Externí odkaz: https://doaj.org/article/937b8deba4f74dbcbaebc04e8417c39a

Biophysical approaches for exploring lipopeptide-lipid interactions

Autor: Renaud Conde, Brandt Bertrand, Sathishkumar Munusamy, Carlos Muñoz-Garay

Publikováno v: Biochimie

In recent years, lipopeptides (LPs) have attracted a lot of attention in the pharmaceutical industry due to their broad-spectrum of antimicrobial activity against a variety of pathogens and their unique mode of action. This class of compounds has eno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d5409aa10e5f34f42b8645b027e0688
http://europepmc.org/articles/PMC7116911