Zobrazeno 1 - 10
of 116
pro vyhledávání: '"pentraxin 3 (ptx3)"'
Autor:
Zhirui Fan, Yuanyuan Zheng, Xiaoli Li, Xiaoming Deng, Yan Ba, Kun Feng, Jin Su, Hui Wang, Zhenhe Suo, Lifeng Li
Publikováno v:
Molecular Therapy: Oncolytics, Vol 24, Iss , Pp 772-787 (2022)
Pentraxin 3 (PTX3) is an inflammatory molecule that is closely related to the proliferation, invasion, and metastasis of cancer. In order to explore the role of PTX3 in the occurrence and development of esophageal carcinoma (ESCA), we modified the PT
Externí odkaz:
https://doaj.org/article/04a8d35c7640466fbf753c8915e9f1e8
Autor:
Anna Paola Capra, Lelio Crupi, Giuseppe Pantò, Alberto Repici, Fabrizio Calapai, Raffaele Squeri, Alessio Ardizzone, Emanuela Esposito
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14195 (2023)
Currently, biological markers for COVID-19 disease severity still constitute the main goal of enhancing an efficient treatment to reduce critical consequences such as an abnormal systemic inflammatory response. In this regard, the latest research has
Externí odkaz:
https://doaj.org/article/f4962d4263a94984ad120cdefb1dd6ea
Autor:
Giuseppe Lapadula, Roberto Leone, Davide Paolo Bernasconi, Andrea Biondi, Emanuela Rossi, Mariella D’Angiò, Barbara Bottazzi, Laura Rachele Bettini, Ilaria Beretta, Cecilia Garlanda, Maria Grazia Valsecchi, Alberto Mantovani, Paolo Bonfanti
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundPTX3 is an important mediator of inflammation and innate immunity. We aimed at assessing its prognostic value in a large cohort of patients hospitalized with COVID-19.MethodsLevels of PTX3 were measured in 152 patients hospitalized with COV
Externí odkaz:
https://doaj.org/article/485a00f885e94117957a1e9ed85ecbd3
Autor:
Yu‐Wei Hsiao, Jhih‐Ying Chi, Chien‐Feng Li, Lei‐Yi Chen, Yi‐Ting Chen, Hsin‐Yin Liang, Yu‐Chih Lo, Jhen‐Yi Hong, Chin‐Pin Chuu, Liang‐Yi Hung, Jyun‐Yi Du, Wen‐Chang Chang, Ju‐Ming Wang
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 1, Pp n/a-n/a (2022)
Abstract Due to the heterogeneity and high frequency of genome mutations in cancer cells, targeting vital protumour factors found in stromal cells in the tumour microenvironment may represent an ideal strategy in cancer therapy. However, the regulati
Externí odkaz:
https://doaj.org/article/57e2d11844154b1fb091704d1e6bfcd8
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 15, p 4384 (2022)
Shigella causes moderate to severe diarrhea or dysentery after invading the colon mucosa. Long Pentraxin 3 (PTX3) is recognized as the humoral component of the innate immune response to bacterial pathogens. We examined the interplay between levels of
Externí odkaz:
https://doaj.org/article/528b44dab22a446f92939ce012e18d93
Autor:
Fatemeh Asgari, Domenico Supino, Raffaella Parente, Nadia Polentarutti, Matteo Stravalaci, Remi Porte, Fabio Pasqualini, Marialuisa Barbagallo, Chiara Perucchini, Camilla Recordati, Elena Magrini, Andrea Mariancini, Federica Riva, Alessia Giordano, Sadaf Davoudian, Thierry Roger, Cornelis van’t Veer, Sebastien Jaillon, Alberto Mantovani, Andrea Doni, Cecilia Garlanda
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Klebsiella pneumoniae is a common pathogen in human sepsis. The emergence of multidrug-resistant K. pneumoniae strains represents a major clinical challenge in nosocomial and community acquired infections. The long pentraxin PTX3, a key component of
Externí odkaz:
https://doaj.org/article/adba4df649134b50a3509fcba851198e
Publikováno v:
Balkan Journal of Medical Genetics, Vol 22, Iss 1, Pp 21-28 (2019)
Pentraxin 3 (PTX3), a prototypical member of the long pentraxin subfamily, is a evolutionarily conserved multimeric pattern recognition receptor involved in the humoral component of the innate immune system. Pentraxin 3 is released when tissue is str
Externí odkaz:
https://doaj.org/article/92d4075ddcde41cdae7e3aad94763f2d
Autor:
Andrea Farini, Chiara Villa, Dario Di Silvestre, Pamela Bella, Luana Tripodi, Rossana Rossi, Clementina Sitzia, Stefano Gatti, Pierluigi Mauri, Yvan Torrente
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Pentraxin 3 (PTX3) is a main component of the innate immune system by inducing complement pathway activation, acting as an inflammatory mediator, coordinating the functions of macrophages/dendritic cells and promoting apoptosis/necrosis. Additionally
Externí odkaz:
https://doaj.org/article/fe9e85ea6ed1469b93e070e89ca1770f
Publikováno v:
Frontiers in Neurology, Vol 10 (2020)
Background: Carotid artery stenosis (CAS), typically resulting from atherosclerotic progression, is more common than intracranial atherosclerotic disease in patients with cerebrovascular disease. Prior literature has incompletely established the rela
Externí odkaz:
https://doaj.org/article/fb3fb9b938b0422d88971f652da7a3d7
Autor:
Michał Kukla, Tomasz Menżyk, Marcin Dembiński, Marek Winiarski, Aleksander Garlicki, Monika Bociąga-Jasik, Magdalena Skonieczna, Dorota Hudy, Barbara Maziarz, Beata Kuśnierz-Cabala, Maria Kapusta, Lubomir Skladany, Ivica Grgurevic, Ivana Mikolasevic, Tajana Filipec-Kanizaj, Małgorzata Wójcik-Bugajska, Tomasz Grodzicki, Tomasz Rogula, Dominika Stygar
Publikováno v:
Biomolecules, Vol 11, Iss 10, p 1422 (2021)
Analysis of liver biopsy specimens showed that SARS-CoV-2 might have led to liver damage. This study aimed to evaluate the role of selected hepatokines and myokines in the development and progression of COVID-19. Seventy patients with laboratory-conf
Externí odkaz:
https://doaj.org/article/614c0c276da24f2b81fcc776d598a6ff