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Akademický článek

Identification and functional analysis of hub genes involved in deoxynivalenol-induced enterotoxicity in porcine (Sus scrofa)

Autor: Jinhua He, Geng Zhao, Mingxia Chen, Ximing Ren, Peizhi Zhu, Zhizhong Liu, Jiayi Zhou, Hanwei Chen, Chuqiao Xiao, Xiang-Guang Li

Publikováno v: Ecotoxicology and Environmental Safety, Vol 290, Iss , Pp 117544- (2025)

Deoxynivalenol (DON) is a type of mycotoxin commonly found in food and animal feed. When consumed, it can have harmful effects on the intestine. The porcine digestive system is physiologically similar to that of humans, making pigs a suitable model f

Externí odkaz: https://doaj.org/article/350aa336f0f446d69927e150481c7911

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Akademický článek

Inhibition of Caspase-1 Ameliorates Ischemia-Associated Blood-Brain Barrier Dysfunction and Integrity by Suppressing Pyroptosis Activation

Autor: Yubin Liang, Pingping Song, Wei Chen, Xuemin Xie, Rixin Luo, Jiehua Su, Yunhui Zhu, Jiamin Xu, Rongrong Liu, Peizhi Zhu, Yusheng Zhang, Min Huang

Publikováno v: Frontiers in Cellular Neuroscience, Vol 14 (2021)

Ischemic cerebral infarction represents a significant cause of disability and death worldwide. Caspase-1 is activated by the NLRP3/ASC pathway and inflammasomes, thus triggering pyroptosis, a programmed cell death. In particular, this death is mediat

Externí odkaz: https://doaj.org/article/fd69841cc5804407ae41049ab6ce824c

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Akademický článek

Bone-targeted methotrexate–alendronate conjugate inhibits osteoclastogenesis in vitro and prevents bone loss and inflammation of collagen-induced arthritis in vivo

Autor: Zi’ang Xie, Guanxiong Liu, Pan Tang, Xuewu Sun, Shuai Chen, An Qin, Peizhi Zhu, Jianfeng Zhang, Shunwu Fan

Publikováno v: Drug Delivery, Vol 25, Iss 1, Pp 187-197 (2018)

Rheumatoid arthritis (RA), a disease that causes joint destruction and bone erosion, is related to osteoclast activity. RA is generally treated with methotrexate (MTX). In this study, a MTX–Alendronate (ALN) conjugate was synthesized and characteri

Externí odkaz: https://doaj.org/article/d64e4f2cd01d41afacab6c9126374ea2

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Akademický článek

Anti-tumor Study of Chondroitin Sulfate-Methotrexate Nanogels

Autor: Jinyu Wang, Weibo Zhao, Haixiao Chen, An Qin, Peizhi Zhu

Publikováno v: Nanoscale Research Letters, Vol 12, Iss 1, Pp 1-8 (2017)

Abstract Self-assembly nanogels (NGs) were formed by bioconjugating methotrexate (MTX) with chondroitin sulfate (CS). MTX-CS NGs can greatly enhance the solubility and improve the delivery efficacy of MTX due to the CD44 binding property of CS. Vivo

Externí odkaz: https://doaj.org/article/8f98fa4be45347d8a38c43cc07c92b4a

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Akademický článek

Preparation and Characterization of Biomimetic Hydroxyapatite Nanocrystals by Using Partially Hydrolyzed Keratin as Template Agent

Autor: Chunxia Gao, Ke Zhao, Liwei Lin, Jinyu Wang, Yang Liu, Peizhi Zhu

Publikováno v: Nanomaterials, Vol 9, Iss 2, p 241 (2019)

Hydroxyapatite (HA), a typical inorganic component of bone, is a widely utilized biomaterial for bone tissue repair and regeneration due to its excellent properties. Inspired by the recent findings on the important roles of protein in biomineralizati

Externí odkaz: https://doaj.org/article/fff917b4be0543cd8d4948e4272ff13e

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Akademický článek

Time-Resolved Study of Nanomorphology and Nanomechanic Change of Early-Stage Mineralized Electrospun Poly(lactic acid) Fiber by Scanning Electron Microscopy, Raman Spectroscopy and Atomic Force Microscopy

Autor: Mengmeng Wang, Yin Cai, Bo Zhao, Peizhi Zhu

Publikováno v: Nanomaterials, Vol 7, Iss 8, p 223 (2017)

In this study, scanning electron microscopy (SEM), Raman spectroscopy and high-resolution atomic force microscopy (AFM) were used to reveal the early-stage change of nanomorphology and nanomechanical properties of poly(lactic acid) (PLA) fibers in a

Externí odkaz: https://doaj.org/article/5dd35a90620343f3bb152878a3810543

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Akademický článek

Synthesis of Ball-Like Ag Nanorod Aggregates for Surface-Enhanced Raman Scattering and Catalytic Reduction

Autor: Wenjing Zhang, Yin Cai, Rui Qian, Bo Zhao, Peizhi Zhu

Publikováno v: Nanomaterials, Vol 6, Iss 6, p 99 (2016)

In this work, ball-like Ag nanorod aggregates have been synthesized via a simple seed-mediated method. These Ag mesostructures were characterized by scanning electron microscope (SEM), transmission electron microscopy (TEM), ultraviolet-visible spect

Externí odkaz: https://doaj.org/article/46bf42a7973a4e48a37c2581f799a753

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Demonstrating the Interfacial Polymer Thermal Transition from Coil-to-Globule to Coil-to-Stretch under Shear Flow Using SFG and MD Simulation

Autor: Yongsheng Luo, Ai-Ping Pang, Peizhi Zhu, Dayang Wang, Xiaolin Lu

Publikováno v: The Journal of Physical Chemistry Letters. 13:1617-1627

Revealing interfacial shear-induced structural responsiveness has long been an important topic in that most fluids in nature and human life are in motion and cause interesting boundary phenomena. It is amazing how the polymer chain conformation or lo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bb4b7bbdcf09156632b2c92d3c188d3
https://doi.org/10.1021/acs.jpclett.1c03866

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