Zobrazeno 1 - 10
of 680
pro vyhledávání: '"peg-ifn"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Background and aimsLimited data have been reported on achieving functional cure using pegylated interferon (Peg-IFN) alpha-2b treatment for postpartum hepatitis B e antigen (HBeAg)-negative women with chronic hepatitis B virus (HBV) infection. This s
Externí odkaz:
https://doaj.org/article/4a3fff43db384556bcaa435c54dca13f
Autor:
Selma El Messaoudi, Ségolène Brichler, Claire Fougerou-Leurent, Emmanuel Gordien, Athenaïs Gerber, Amal Kortebi, Garance Lagadic, Miroslava Subic-Levrero, Sophie Metivier, Stanislas Pol, Anne Minello, Vlad Ratziu, Vincent Leroy, Philippe Mathurin, Laurent Alric, Fatoumata Coulibaly, Jean-Michel Pawlotsky, Fabien Zoulim, Victor de Lédinghen, Jérémie Guedj
Publikováno v:
JHEP Reports, Vol 6, Iss 8, Pp 101070- (2024)
Background & Aims: Bulevirtide is a first-in-class entry inhibitor antiviral treatment for chronic hepatitis D. The viral kinetics during bulevirtide therapy and the effect of combining bulevirtide with pegylated-interferon (Peg-IFN) are unknown. Met
Externí odkaz:
https://doaj.org/article/73e8c7b7ac3f4fe3a3996b07dd278246
Publikováno v:
Virology Journal, Vol 20, Iss 1, Pp 1-11 (2023)
Abstract Objective To investigate whether the expression of triple motif protein 19/38 (TRIM19/38) mRNA in peripheral blood mononuclear cells (PBMCs) of HBeAg-negative chronic hepatitis B virus (HBV) carriers is associated with the response to pegyla
Externí odkaz:
https://doaj.org/article/98028fc06d0d4ba9b84777ebaeb12843
Autor:
Li-Li Wu, Xiao-Yan Li, Kai Deng, Bing-Liang Lin, Hong Deng, Dong-Ying Xie, Geng-Lin Zhang, Qi-Yi Zhao, Zhi-Shuo Mo, Yue-Hua Huang, Zhi-Liang Gao
Publikováno v:
Liver Research, Vol 7, Iss 2, Pp 136-144 (2023)
Background and aims: The primary goal of chronic hepatitis B (CHB) treatment is to reduce hepatitis B surface antigen (HBsAg). T helper 17 (Th17) and regulatory T (Treg) cells are essential for the development of CHB. However, how Th17 and Treg cells
Externí odkaz:
https://doaj.org/article/8d959db95e01445fb794174860636754
Autor:
Shengxia Yin, Yawen Wan, Rahma Issa, Yijia Zhu, Xiaoming Xu, Jiacheng Liu, Minxin Mao, Ming Li, Xin Tong, Chen Tian, Jian Wang, Rui Huang, Qun Zhang, Chao Wu, Yuxin Chen, Jie Li
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
Indices for predicting HBsAg or HBeAg seroconversion in patients with chronic hepatitis B virus (HBV) infection during antiviral therapy remain elusive. We aimed to investigate if the presence of HBsAb-specific B cells at baseline can predict HBsAg o
Externí odkaz:
https://doaj.org/article/c8af4198e7ea45f6858f1002c9e3681b
Akademický článek
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Publikováno v:
International Journal of General Medicine, Vol Volume 15, Pp 4441-4451 (2022)
Li Zhu,1– 3,* Jin Li,4,5,* Junchi Xu,4,5 Fan Chen,2,3 Xunxun Wu,2,3 Chuanwu Zhu1– 3 1Department of Infectious Diseases, the Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People’s Republic of China; 2Department of He
Externí odkaz:
https://doaj.org/article/a10e47a31baf4feb82a2a84e8a40bada
Publikováno v:
Di-san junyi daxue xuebao, Vol 44, Iss 2, Pp 155-161 (2022)
Objective To evaluate the predictive efficacy of serum pregenomic RNA (pgRNA) level in HBeAg clearance for chronic hepatitis B (CHB) patients treated with polyethylene glycol interferon alfa (PEG-IFN-α). Methods Twenty-five CHB patients with HBeAg p
Externí odkaz:
https://doaj.org/article/2d32ec3369e44843b251b4431b18c142
Autor:
Yifei Guo, Jiajia Han, Yongmei Zhang, Chengmeng Jin, Yao Zhang, Jingjing He, Shiqi Chen, Yue Guo, Yanxue Lin, Fahong Li, Feifei Yang, Zhongliang Shen, Richeng Mao, Haoxiang Zhu, Jiming Zhang
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
BackgroundHepatitis B surface antigen (HBsAg) loss, namely, the functional cure, can be achieved through the pegylated interferon (PEG-IFN)-based therapy. However, it is an unignorable fact that a small proportion of patients who achieved functional
Externí odkaz:
https://doaj.org/article/222ac99b519942649fd73d1499757260
Autor:
Xiaoyue Bi, Si Xie, Shuling Wu, Weihua Cao, Yanjie Lin, Liu Yang, Tingting Jiang, Wen Deng, Shiyu Wang, Ruyu Liu, Yuanjiao Gao, Ge Shen, Min Chang, Hongxiao Hao, Mengjiao Xu, Xiaoxue Chen, Leiping Hu, Yao Lu, Lu Zhang, Yao Xie, Minghui Li
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundTo investigate the changes of natural killer (NK) cell phenotype in the interferon alpha (IFN-α) treatment of chronic hepatitis B (CHB) and its relationship with clinical indicators.MethodsThe CHB patients who did not receive any antiviral
Externí odkaz:
https://doaj.org/article/e768f1025d984b57bcb8491541f1e347