Zobrazeno 1 - 10
of 600
pro vyhledávání: '"pdl-1"'
Autor:
Sevda Jafari, Alireza Khodaei Ardakan, Elnaz Mehdizadeh Aghdam, Asghar Mesbahi, Soheila Montazersaheb, Ommoleila Molavi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Chrysin is a natural flavonoid with anti-cancer effects. Despite its beneficial effects, little information is available regarding its immunogenic cell death (ICD) properties. In this work, we hypothesized that chrysin can potentiate radioth
Externí odkaz:
https://doaj.org/article/64ba70fe3c1d42a88e2fd9c1c8d8ce3d
Publikováno v:
Medical Journal of Babylon, Vol 21, Iss 3, Pp 659-663 (2024)
Background:A programed death ligand L1 is the particular PD-1 ligand that is primarily found in lymphoid, epithelial, and myeloid cells. In order to activate the PD-1/PD-L1 pathway, which suppresses the production of cytokines and controls immune fun
Externí odkaz:
https://doaj.org/article/9160b58ca95a47aa935a40227178d1d0
Publikováno v:
Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-9 (2024)
Abstract Background B-Raf mutation positivity, B-Raf mutation positivity occurrence with programmed death ligand 1 overexpression, and musculoskeletal metastasis are singly rare in non-small cell lung cancer, and even rarer is all occurring in one pa
Externí odkaz:
https://doaj.org/article/5245cc4e3fef4493bdee96aa9690c47e
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 7812-7831 (2024)
The intestinal microbiota and the human body are in a permanent interaction. There is a symbiotic relationship in which the microbiota plays a vitally important role in the performance of numerous functions, including digestion, metabolism, the devel
Externí odkaz:
https://doaj.org/article/12b17b16d01046a4ba533de0f3cd04c8
Autor:
Shepherd Nhamoyebonde, Mark Chambers, Lerato Ndlovu, Farina Karim, Matilda Mazibuko, Zoey Mhlane, Lindiwe Madziwa, Yunus Moosa, Sashen Moodley, Monjurul Hoque, Alasdair Leslie
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionNeutrophils play a complex and important role in the immunopathology of TB. Data suggest they are protective during early infection but become a main driver of immunopathology if infection progresses to active disease. Neutrophils are now
Externí odkaz:
https://doaj.org/article/d18491f9235746e3b939ef9df4997977
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Immune escape, a process by which tumor cells evade immune surveillance, remains a challenge for cancer therapy. Tumor cells produce extracellular vesicles (EVs) that participate in immune escape by transferring bioactive molecule
Externí odkaz:
https://doaj.org/article/e86316ffe88945428b8815bbc7b10dd6
Autor:
Francesco Vitiello, Stefano Cereda, Silvia Foti, Nicole Liscia, Elena Mazza, Monica Ronzoni, Stefano Cascinu
Publikováno v:
Immunological Medicine, Vol 47, Iss 1, Pp 1-5 (2024)
AbstractSmall bowel adenocarcinoma (SBA) is a rare tumor with an unfavorable prognosis, and due to its rarity, few studies on its treatment are available. Chemotherapy remains the standard of treatment in advanced disease. Recently immunotherapy has
Externí odkaz:
https://doaj.org/article/6b99de4964474cd4b9d0055f294478ae
Autor:
Gunnar Wagenius, Anders Vikström, Anders Berglund, Stina Salomonsson, Goran Bencina, Xiaohan Hu, Dana Chirovsky, Hans Brunnström
Publikováno v:
Acta Oncologica, Vol 63, Iss 1 (2024)
Background and purpose: The treatment landscape for patients with advanced non-small cell lung cancer (NSCLC) has evolved significantly since the introduction of immunotherapies. We here describe PD-L1 testing rates, treatment patterns, and real-worl
Externí odkaz:
https://doaj.org/article/a1e8d079c2b248daaad858a25b0a9fc4
Autor:
Nicolas Roussot, Jean-David Fumet, Emeric Limagne, Marion Thibaudin, Alice Hervieu, Audrey Hennequin, Sylvie Zanetta, Lorraine Dalens, Théo Fourrier, Loick Galland, Pierre Jacob, Aurélie Bertaut, Emilie Rederstorff, Cédric Chevalier, Sarah Ghirardi, Elodie Gilbert, Azzat Khoukaz, Etienne Martin, Constance Nicolet, Magali Quivrin, David Thibouw, Noémie Vulquin, Gilles Truc, Magali Rouffiac, Francois Ghiringhelli, Céline Mirjolet
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Background Immunotherapy targeting the PD-1/PD-L1 pathway is a standard of care in a number of metastatic malignancies, but less than a fifth of patients are expected to respond to ICIs (Immune Checkpoint Inhibitors). In a clinical trial, co
Externí odkaz:
https://doaj.org/article/a9a844b15014448f8d6e92baf2f9b80d
Publikováno v:
Dermatology Practical & Conceptual, Vol 14, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/5dbc674cc2a5471ca6415e34c031ab49