Zobrazeno 1 - 10
of 2 733
pro vyhledávání: '"pde5"'
Autor:
Georgios Kallinikas, Georgios Haronis, Eirini Kallinika, Diomidis Kozyrakis, Evangelos Rodinos, Athanasios Filios, Panagiotis Filios, Despoina Mityliniou, Konstantinos Safioleas, Anastasios Zarkadas, Dimitrios Bozios, Athanasios Karmogiannis, Vasileios Konstantinopoulos, Anna Maria Konomi, Amin M. Ektesabi, James N. Tsoporis
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10704 (2024)
Diabetic bladder dysfunction (DBD) comprises a wide spectrum of lower urinary tract symptoms that impact diabetic patients’ lives, including urinary frequency, urgency, incontinence, and incomplete bladder emptying. To relieve symptoms, anticholine
Externí odkaz:
https://doaj.org/article/38ef1c6176fa484aa3d5e9a864ce8296
Efficacy and safety of PDE5 inhibitors in middle-aged and old patients with and without hypogonadism
Autor:
Chunlin Wang, Hui Zhang, Fu Wang, Jun Guo, Jianlin Yuan, Guangdong Hou, Ming Gao, Zheng Li, Yan Zhang
Publikováno v:
The Aging Male, Vol 27, Iss 1 (2024)
AbstractPurpose Although several reviews have evaluated the use of PDE5 inhibitors (PDE5i) for treating erectile dysfunction (ED), their specific use in middle-aged and old patients has not been fully evaluated. Given that elderly patients with ED of
Externí odkaz:
https://doaj.org/article/911dce18c1a946168e3d1d7aadda29c9
Publikováno v:
Quality in Sport, Vol 17 (2024)
Diabetes mellitus (DM) significantly increases the risk of erectile dysfunction (ED), affecting up to 52% of diabetic males. This review examines the epidemiology, pathophysiology, and treatment modalities of ED in diabetic patients. Key factors infl
Externí odkaz:
https://doaj.org/article/92df0271376a49b1bb835d2f19a1aa95
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Introduction: In clinical practice, phosphodiesterase 5 (PDE5) inhibitors are commonly used to treat erectile dysfunction and pulmonary arterial hypertension. However, due to the high structural similarity between PDE5 and Phosphodiesterase 6 (PDE6),
Externí odkaz:
https://doaj.org/article/8a7c4f8b72fa40868a68c25638e19ed3
Autor:
Zhenzhan Zhang, Donghua Huang, Junjie Feng, Wangji Li, Zhe Wang, Mengting Lu, Yangyang Luo, Weihao Yang, Zhou Xu, Qingfeng Xie, Wenfu Ding, Xin Tan, Wenjun He, Guoxin Li, Hao Liu, Shangtong Lei
Publikováno v:
Interdisciplinary Medicine, Vol 2, Iss 3, Pp n/a-n/a (2024)
Abstract Phosphodiesterase‐5 (PDE5) inhibitors are used clinically for the treatment of erectile dysfunction, pulmonary arterial hypertension, and other urological diseases. Emerging evidences have suggested the therapeutic capacity of PDE5 inhibit
Externí odkaz:
https://doaj.org/article/8ecf088bae654fe9963db98dcbb7270a
Autor:
Wuqing Huang, Xi Yang, Naiqi Zhang, Keyuan Chen, Jun Xiao, Zhihuang Qiu, Sujun You, Ziting Gao, Jianguang Ji, Liangwan Chen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116710- (2024)
PDE5 inhibitors was reported to play a protective role in both regulating lipid metabolism and reducing heart failure (HF). This study aimed to clarify the effectiveness of PDE5 inhibitors against hyperlipidemia-related HF by combining evidence from
Externí odkaz:
https://doaj.org/article/1c0e16c581554bfbaaee7a648c56d577
Akademický článek
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Autor:
Hamit Hakan Alp, Zübeyir Huyut, murat Cihan, Mehmet Ramazan Şekeroğlu, Gülşah Alyar, Serkan Yildirim, Bünyamin Uçar, Halil İbrahim Akbay
Publikováno v:
Van Tıp Dergisi, Vol 30, Iss 3, Pp 269-278 (2023)
INTRODUCTION: Osteoporosis is an important health problem and there is no effective treatment yet. phosphodiesterase 5 inhibitors are promising agents for the treatment of osteoporosis. In this study, we aimed to determine the effects of phosphodiest
Externí odkaz:
https://doaj.org/article/a9e3cab11fd34b9d9d5d81e32c40fed6
Publikováno v:
Plants, Vol 13, Iss 11, p 1518 (2024)
Cinnamomum osmophloeum Kanehira (CO) is an endemic species of Taiwan. This study elucidated the composition of CO hydrosol, revealing trans-cinnamaldehyde (65.03%), trans-cinnamyl acetate (7.57%), and coumarin (4.31%) as the main volatile compounds.
Externí odkaz:
https://doaj.org/article/c2ac1a72ce2c4535a4ab74f5248d058a
Autor:
Kurt Miller, Uwe May, Wolf-Dietrich Beecken, Georgios Hatzichristodoulou, Michael Böhm, Stefan Fink
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
An evidence-based consensus meeting was held with urologists, a pharmacist and a cardiologist to perform a structured benefit-risk analysis of reclassifying tadalafil, a phosphodiesterase type 5 (PDE5) inhibitor for treatment of erectile dysfunction
Externí odkaz:
https://doaj.org/article/cbd36f2815c04b41b7c11af8a38d2d05