Zobrazeno 1 - 10
of 45
pro vyhledávání: '"pd therapy"'
Publikováno v:
Bioactive Materials, Vol 25, Iss , Pp 689-700 (2023)
The low objective response rates and severe side effects largely limit the clinical outcomes of immune checkpoint blockade (ICB) therapy. Here, a tumor “self-killing” therapy based on gene-guided OX40L anchoring to tumor cell membrane was reporte
Externí odkaz:
https://doaj.org/article/d7e24fd3b4e2431ab75ce8a0fa3cc534
Autor:
Kai Zhang, Shiou Zhu, Jiamei Li, Tingting Jiang, Lu Feng, Junping Pei, Guan Wang, Liang Ouyang, Bo Liu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3015-3034 (2021)
Parkinson's disease (PD), known as one of the most universal neurodegenerative diseases, is a serious threat to the health of the elderly. The current treatment has been demonstrated to relieve symptoms, and the discovery of new small-molecule compou
Externí odkaz:
https://doaj.org/article/2f99c69d80204691acdb51aafb492f32
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
With programmed death 1/ligand 1 (PD-1/PD-L1) as the cornerstone, anti-PD antibodies have pioneered revolutionary immunotherapies for malignancies. But most patients struggled to respond to anti-PD owing to primary or acquired resistance or even hype
Externí odkaz:
https://doaj.org/article/7347ffca46734a8db5796dcc024cf182
Autor:
Ewelina Palasz, Adrianna Wysocka, Anna Gasiorowska, Malgorzata Chalimoniuk, Wiktor Niewiadomski, Grazyna Niewiadomska
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1170 (2020)
Brain-derived neurotrophic factor (BDNF) promotes neuroprotection and neuroregeneration. In animal models of Parkinson’s disease (PD), BDNF enhances the survival of dopaminergic neurons, improves dopaminergic neurotransmission and motor performance
Externí odkaz:
https://doaj.org/article/1efc307179474d6a9340704c0c7c86c2
Autor:
Lu Feng, Kai Zhang, Bo Liu, Tingting Jiang, Liang Ouyang, Guan Wang, Jiamei Li, Shiou Zhu, Junping Pei
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3015-3034 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Parkinson's disease (PD), known as one of the most universal neurodegenerative diseases, is a serious threat to the health of the elderly. The current treatment has been demonstrated to relieve symptoms, and the discovery of new small-molecule compou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d12dab43aca56bfd6a912c2aa71297ff
http://www.sciencedirect.com/science/article/pii/S2211383521000642
http://www.sciencedirect.com/science/article/pii/S2211383521000642
Autor:
Zhi Dong Zhou, Shao Ping Xie, Wuan Ting Saw, Patrick Ghim Hoe Ho, Hong Yan Wang, Lei Zhou, Yi Zhao, Eng King Tan
Publikováno v:
Cells, Vol 8, Iss 8, p 911 (2019)
Accumulative evidence indicated that the pathologically accumulated metal ions (iron species and Mn3+) and abnormally up-regulated monoamine oxidase B (MAOB) activity induced oxidation of endogenous dopamine (DA) can lead to mitochondria impairment,
Externí odkaz:
https://doaj.org/article/cf5f1a0a519c46a884f5665529f4eb61
Akademický článek
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Autor:
Surbhi Mishra, Sajeen Bahadur Amatya, Sonja Salmi, Vesa Koivukangas, Peeter Karihtala, Justus Reunanen
Publikováno v:
Cancers. 14:5121
Cancer is a deadly disease worldwide. In light of the requisite of convincing therapeutic methods for cancer, immune checkpoint inhibition methods such as anti-PD-1/PD-L1 therapy appear promising. Human microbiota have been exhibited to regulate susc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7314fb317264d7a629a21169a6b1da1d
https://doi.org/10.3390/cancers14205121
https://doi.org/10.3390/cancers14205121
Akademický článek
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Akademický článek
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