Zobrazeno 1 - 10
of 2 563
pro vyhledávání: '"pc12 cell"'
Autor:
Dianmei Yu, Haiyan Wang, Yiwen Zhai, Zhixiang Lei, Minglu Sun, Si Chen, Panfeng Yin, Xianchun Wang
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-16 (2024)
Abstract Background Parkinson’s disease (PD) is characterized by death of dopaminergic neurons leading to dopamine deficiency, excessive α-synuclein facilitating Lewy body formation, etc. Latroeggtoxin-VI (LETX-VI), a proteinaceous neurotoxin disc
Externí odkaz:
https://doaj.org/article/fd3c1276d8864f32828e25c9e1180204
Autor:
Seda Şirin
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 10, Pp 8071-8090 (2023)
Parabiotics, including L-EPSs, have been administered to patients with neurodegenerative disorders. However, the antioxidant properties of L-EPSs against H2O2-induced oxidative stress in PC12 cells have not been studied. Herein, we aimed to investiga
Externí odkaz:
https://doaj.org/article/c329388f29474a88a9f4850543645a98
Autor:
Dianmei Yu, Haiyan Wang, Zhixiang Lei, Yiwen Zhai, Si Chen, Minglu Sun, Panfeng Yin, Xianchun Wang
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background Previous preliminary work found that Latroeggtoxin-VI (LETX-VI), a proteinaceous neurotoxin from the eggs of spider Latrodectus tredecimguttatus, could promote the synthesis and release of dopamine in PC12 cells. However, the unde
Externí odkaz:
https://doaj.org/article/d7e44017c4344322aa401305f110a560
Publikováno v:
Ultrasonics Sonochemistry, Vol 101, Iss , Pp 106678- (2023)
Two-dimensional (2D) biomaterials, with unique planar topology and quantum effect, have been widely recognized as a versatile nanoplatform for bioimaging, drug delivery and tissue engineering. However, during the complex application of nerve repair,
Externí odkaz:
https://doaj.org/article/62e44121989042a8b3b78a73934d21f8
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 11, Pp 2514-2519 (2023)
Parkinson’s disease is a neurodegenerative disorder, and ferroptosis plays a significant role in the pathological mechanism underlying Parkinson’s disease. Rapamycin, an autophagy inducer, has been shown to have neuroprotective effects in Parkins
Externí odkaz:
https://doaj.org/article/2fae63904c944d4ea5fd691cac2d404f
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 3, Pp 618-625 (2023)
Studies on ischemia/reperfusion (I/R) injury suggest that exogenous neural stem cells (NSCs) are ideal candidates for stem cell therapy reperfusion injury. However, NSCs are difficult to obtain owing to ethical limitations. In addition, the survival,
Externí odkaz:
https://doaj.org/article/283a68f20a8546fa8870754e74ce1d2d
Publikováno v:
Jichu yixue yu linchuang, Vol 42, Iss 12, Pp 1873-1878 (2022)
Objective To study the effect of miR-499a-5p on injury induced by chemical hypoxia of pheochromocytoma cell(PC12). Methods PC12 cells were divided into control group, hypoxia group (treated with CoCl2 for 24 h), hypoxia+miR-NC or miR-mimic groups. Ce
Externí odkaz:
https://doaj.org/article/264d695ba68941c5a4f0ce09f597ebb3
Autor:
Bingxian Zhang, Ning Zhou, Zhenkai Zhang, Ruifeng Wang, Long Chen, Xiaoke Zheng, Weisheng Feng
Publikováno v:
Molecules, Vol 29, Iss 7, p 1497 (2024)
Iridoid components have been reported to have significant neuroprotective effects. However, it is not yet clear whether the efficacy and mechanisms of iridoid components with similar structures are also similar. This study aimed to compare the neurop
Externí odkaz:
https://doaj.org/article/a89343612b2a4b4383e9a3095f402780
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