Zobrazeno 1 - 10
of 28
pro vyhledávání: '"patient‐derived explant"'
Autor:
Denis Belitškin, Pauliina Munne, Shishir M. Pant, Johanna M. Anttila, Ilida Suleymanova, Kati Belitškina, Daniel Kirchhofer, James Janetka, Taivo Käsper, Sami Jalil, Jeroen Pouwels, Topi A. Tervonen, Juha Klefström
Publikováno v:
Molecular Oncology, Vol 18, Iss 3, Pp 547-561 (2024)
Hepsin, a type II transmembrane serine protease, is commonly overexpressed in prostate and breast cancer. The hepsin protein is stabilized by the Ras‐MAPK pathway, and, downstream, this protease regulates the degradation of extracellular matrix com
Externí odkaz:
https://doaj.org/article/3e25433eb30948a582897944f0e227ae
Akademický článek
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Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 2, Pp n/a-n/a (2021)
Abstract Carcinomas are complex heterocellular systems containing epithelial cancer cells, stromal fibroblasts, and multiple immune cell‐types. Cell‐cell communication between these tumor microenvironments (TME) and cells drives cancer progressio
Externí odkaz:
https://doaj.org/article/184de529423d4e5fa321067eee5ab70d
Autor:
Collin Gilbreath, Shihong Ma, Lan Yu, Rajni Sonavane, Carlos M. Roggero, Anvita Devineni, Ryan Mauck, Neil B. Desai, Aditya Bagrodia, Ralf Kittler, Ganesh V. Raj, Yi Yin
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100898- (2021)
The study of DNA damage repair response (DDR) in prostate cancer is restricted by the limited number of prostate cancer cell lines and lack of surrogates for heterogeneity in clinical samples. Here, we sought to leverage our experience with patient d
Externí odkaz:
https://doaj.org/article/81556393fb8f47888a4c4ffdabdcfa43
Autor:
Margaret M. Centenera, Theresa E. Hickey, Shalini Jindal, Natalie K. Ryan, Preethi Ravindranathan, Hisham Mohammed, Jessica L. Robinson, Matthew J. Schiewer, Shihong Ma, Payal Kapur, Peter D. Sutherland, Clive E. Hoffmann, Claus G. Roehrborn, Leonard G. Gomella, Jason S. Carroll, Stephen N. Birrell, Karen E. Knudsen, Ganesh V. Raj, Lisa M. Butler, Wayne D. Tilley
Publikováno v:
Molecular Oncology, Vol 12, Iss 9, Pp 1608-1622 (2018)
Breast and prostate cancer research to date has largely been predicated on the use of cell lines in vitro or in vivo. These limitations have led to the development of more clinically relevant models, such as organoids or murine xenografts that utiliz
Externí odkaz:
https://doaj.org/article/0552f838da6a4c13b4e0ce9e34c20273
Autor:
Margaret M. Centenera, Andrew D. Vincent, Max Moldovan, Hui-Ming Lin, David J. Lynn, Lisa G. Horvath, Lisa M. Butler
Publikováno v:
Cancers; Volume 14; Issue 7; Pages: 1708
Prostate cancer is a complex and heterogeneous disease, but a small number of cell lines have dominated basic prostate cancer research, representing a major obstacle in the field of drug and biomarker discovery. A growing lack of confidence in cell l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd7c2fe23738138565e94e5ee6ea0f0
Autor:
Rajni Sonavane, Ganesh V. Raj, Aditya Bagrodia, Anvita Devineni, Ralf Kittler, Yi Yin, Lan Yu, Collin Gilbreath, Carlos M. Roggero, Shihong Ma, Neil Desai, Ryan Mauck
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100898-(2021)
Translational Oncology
Translational Oncology
The study of DNA damage repair response (DDR) in prostate cancer is restricted by the limited number of prostate cancer cell lines and lack of surrogates for heterogeneity in clinical samples. Here, we sought to leverage our experience with patient d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1164d4d83ffc7f1b2c90713b27a88d
http://www.sciencedirect.com/science/article/pii/S1936523320303909
http://www.sciencedirect.com/science/article/pii/S1936523320303909
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Kelly J. Gregory, Stephanie M Morin, Alex Kubosiak, Benjamin J Schalet, Jennifer Ser-Dolansky, Sallie S. Schneider, D. Joseph Jerry
Publikováno v:
Immunology and Cell Biology
Ex vivo mammary explant systems are an excellent model to study interactions between epithelium and stromal cell types because they contain physiologically relevant heterotypic interactions in the background of genetically diverse patients. The intac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa9b2e69ca31742c55068d108d8ad4f
https://pubmed.ncbi.nlm.nih.gov/32713010
https://pubmed.ncbi.nlm.nih.gov/32713010