Zobrazeno 1 - 2
of 2
pro vyhledávání: '"pathology [Rhombencephalon]"'
Deficiency in the mRNA export mediator Gle1 impairs Schwann cell development in the zebrafish embryo
Autor:
Basil Sharrack, H.R. Kim, Ke Ning, N.I. Alsomali, Jonathan D. Wood, Tennore Ramesh, Chiara F. Valori, A. Seytanoglu, Alan T McGown, Mimoun Azzouz
Publikováno v:
Neuroscience 322, 287-297 (2016). doi:10.1016/j.neuroscience.2016.02.039
GLE1 mutations cause lethal congenital contracture syndrome 1 (LCCS1), a severe autosomal recessive fetal motor neuron disease, and more recently have been associated with amyotrophic lateral sclerosis (ALS). The gene encodes a highly conserved prote
Autor:
Thomas Ulas, Toni Schumacher, Walker S. Jackson, Khalid Tai, Melvin Schleif, Joachim L. Schultze, Cordula Rakers, Santiago Valle Torres, Hana Matuskova, Kristian Händler, Gabor C. Petzold, Nelli Blank
Publikováno v:
Glia 67(4), 619-633 (2018). doi:10.1002/glia.23544
Glia
Glia
Astrocytes support normal brain function, but may also contribute to neurodegeneration when they become reactive under pathological conditions such as stroke. However, the molecular underpinnings of this context‐dependent interplay between benefici