Zobrazeno 1 - 10
of 21
pro vyhledávání: '"pathology [Nerve Net]"'
Autor:
Bernhard Bogerts, Henrik Dobrowolny, Berend Malchow, Thomas Schneider-Axmann, Christoph Schmitz, Florian Raabe, Peter Falkai, Andrea Schmitt, Ludovico Cantuti-Castelvetri, Johann Steiner, Laura Tatsch, Mikael Simons, Verena Huber, Lenka Slapakova
Publikováno v:
European archives of psychiatry and clinical neuroscience 270(4), 413-424 (2019). doi:10.1007/s00406-019-01067-0
In schizophrenia, decreased hippocampal volume, reduced oligodendrocyte numbers in hippocampal cornu ammonis (CA) subregions and reduced neuron number in the dentate gyrus have been reported; reduced oligodendrocyte numbers were significantly related
Autor:
Ewa Baczynska, David Baidoe-Ansah, Jakub Wlodarczyk, Luisa Strackeljan, Alexander Dityatev, Rahul Kaushik, Carla Cangalaya
Publikováno v:
Cells
Cells 10(8), 1862 (2021). doi:10.3390/cells10081862
Cells, Vol 10, Iss 1862, p 1862 (2021)
Volume 10
Issue 8
Cells 10(8), 1862 (2021). doi:10.3390/cells10081862
Cells, Vol 10, Iss 1862, p 1862 (2021)
Volume 10
Issue 8
The extracellular matrix (ECM) plays a key role in synaptogenesis and the regulation of synaptic functions in the central nervous system. Recent studies revealed that in addition to dopaminergic and serotoninergic neuromodulatory systems, microglia a
Autor:
Keith W. Muir, Martin Ebinger, Christian Gerloff, Thies Ingwersen, Salvador Pedraza, Alina Königsberg, Claus Z Simonsen, Götz Thomalla, Josep Puig, Eckhard Schlemm, Jochen B. Fiebach, Jens Fiehler, Anke Wouters, Bastian Cheng, Vincent Thijs, Ivana Galinovic, Matthias Endres, Florent Boutitie, Robin Lemmens, Norbert Nighoghossian
Publikováno v:
Nature Communications 12(1), 2590 (2021). doi:10.1038/s41467-021-22786-w
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.2590. ⟨10.1038/s41467-021-22786-w⟩
Nature Communications, 2021, 12 (1), pp.2590. ⟨10.1038/s41467-021-22786-w⟩
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Schlemm, E, Ingwersen, T, Königsberg, A, Boutitie, F, Ebinger, M, Endres, M, Fiebach, J B, Fiehler, J, Galinovic, I, Lemmens, R, Muir, K W, Nighoghossian, N, Pedraza, S, Puig, J, Simonsen, C Z, Thijs, V, Wouters, A, Gerloff, C, Thomalla, G & Cheng, B 2021, ' Preserved structural connectivity mediates the clinical effect of thrombolysis in patients with anterior-circulation stroke ', Nature Communications, vol. 12, no. 1, 2590 . https://doi.org/10.1038/s41467-021-22786-w
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.2590. ⟨10.1038/s41467-021-22786-w⟩
Nature Communications, 2021, 12 (1), pp.2590. ⟨10.1038/s41467-021-22786-w⟩
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Schlemm, E, Ingwersen, T, Königsberg, A, Boutitie, F, Ebinger, M, Endres, M, Fiebach, J B, Fiehler, J, Galinovic, I, Lemmens, R, Muir, K W, Nighoghossian, N, Pedraza, S, Puig, J, Simonsen, C Z, Thijs, V, Wouters, A, Gerloff, C, Thomalla, G & Cheng, B 2021, ' Preserved structural connectivity mediates the clinical effect of thrombolysis in patients with anterior-circulation stroke ', Nature Communications, vol. 12, no. 1, 2590 . https://doi.org/10.1038/s41467-021-22786-w
Thrombolysis with recombinant tissue plasminogen activator in acute ischemic stroke aims to restore compromised blood flow and prevent further neuronal damage. Despite the proven clinical efficacy of this treatment, little is known about the short-te
Autor:
Ballarini, Tommaso, Albrecht, Franziska, Synofzik, Matthis, Wiltfang, Jens, Germany, FTLD Consortium, 4RTNI, Otto, Markus, Schroeter, Matthias L, Mueller, Karsten, Jech, Robert, Diehl-Schmid, Janine, Fliessbach, Klaus, Kassubek, Jan, Lauer, Martin, Fassbender, Klaus, Schneider, Anja
Publikováno v:
NeuroImage: Clinical
NeuroImage: Clinical 25, 102112 (2020). doi:10.1016/j.nicl.2019.102112
NeuroImage : Clinical
NeuroImage: Clinical, Vol 25, Iss, Pp-(2020)
NeuroImage: Clinical 25, 102112 (2020). doi:10.1016/j.nicl.2019.102112
NeuroImage : Clinical
NeuroImage: Clinical, Vol 25, Iss, Pp-(2020)
Highlights • Does corticobasal syndrome (CBS) alter brain volume and functional connectivity? • Brain volume changes are severe and widespread in CBS compared to controls. • CBS shows both decreases and increases in brain functional connectivit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2af1a8c5752119810ea7477d63b56c
https://hdl.handle.net/21.11116/0000-0005-4E0C-821.11116/0000-0005-619A-0
https://hdl.handle.net/21.11116/0000-0005-4E0C-821.11116/0000-0005-619A-0
Autor:
Alexander N.W. Taylor, Robert Stahl, Katharina Buerger, Miguel Ángel Araque Caballero, Michael Ewers, Martin Dichgans, Lana Kambeitz-Ilankovic, Julia Hartmann, Daniel Janowitz, Lee Simon-Vermot, Birgit Ertl-Wagner, Claudia Mueller, Marco Duering, Nicolai Franzmeier, Cihan Catak
Publikováno v:
Journal of Alzheimer's Disease
Journal of Alzheimer's disease 59(4), 1381-1392 (2017). doi:10.3233/JAD-170360
Journal of Alzheimer's disease 59(4), 1381-1392 (2017). doi:10.3233/JAD-170360
Reserve in aging and Alzheimer's disease (AD) is defined as maintaining cognition at a relatively high level in the presence of neurodegeneration, an ability often associated with higher education among other life factors. Recent evidence suggests th
Autor:
Rittman, Timothy, Borchert, Robin, Frisoni, Giovanni B, Rosser, Martin, Santiago, Beatriz, Scarpini, Elio, Schönecker, Sonja, Semler, Elisa, Shafei, Rachelle, Shoesmith, Christen, Tábuas-Pereira, Miguel, Tainta, Mikel, Taipa, Ricardo, Laforce, Robert, Tang-Wai, David, Thomas, David L, Thonberg, Hakan, Timberlake, Carolyn, Tiraboschi, Pietro, Vandamme, Philip, Vandenbulcke, Mathieu, Veldsman, Michele, Verdelho, Ana, Villanua, Jorge, Finger, Elizabeth, Warren, Jason, Wilke, Carlo, Woollacott, Ione, Wlasich, Elisabeth, Zetterberg, Henrik, Zulaica, Miren, Mendonça, Alexandre, Sorbi, Sandro, Rohrer, Jonathan D, Rowe, James B, Initiative, Genetic Frontotemporal Dementia, Afonso, Sónia, Almeida, Maria Rosario, Jones, Simon, Anderl-Straub, Sarah, Andersson, Christin, Antonell, Anna, Archetti, Silvana, Arighi, Andrea, Balasa, Mircea, Barandiaran, Myriam, Bargalló, Nuria, Bartha, Robart, Bender, Benjamin, van Swieten, John, Benussi, Luisa, Bessi, Valentina, Binetti, Giuliano, Black, Sandra, Bocchetta, Martina, Borrego-Ecija, Sergi, Bras, Jose, Bruffaerts, Rose, Caroppo, Paola, Cash, David, Borroni, Barbara, Castelo-Branco, Miguel, Convery, Rhian, Cope, Thomas, Cosseddu, Maura, de Arriba, María, Di Fede, Giuseppe, Díaz, Zigor, Dick, Katrina M, Duro, Diana, Fenoglio, Chiara, Galimberti, Daniela, Ferrari, Camilla, Ferreira, Catarina B, Flanagana, Toby, Fox, Nick, Freedman, Morris, Fumagalli, Giorgio, Gabilondo, Alazne, Gasparotti, Roberto, Gauthier, Serge, Gazzina, Stefano, Masellis, Mario, Ghidoni, Roberta, Giaccone, Giorgio, Gorostidi, Ana, Greaves, Caroline, Guerreiro, Rita, Heller, Carolin, Hoegen, Tobias, Indakoetxea, Begoña, Jelic, Vesna, Jiskoot, Lize, Tartaglia, Maria Carmela, Karnath, Hans-Otto, Keren, Ron, Leitão, Maria João, Lladó, Albert, Lombardi, Gemma, Loosli, Sandra, Maruta, Carolina, Mead, Simon, Meeter, Lieke, Miltenberger, Gabriel, Graff, Caroline, van Minkelen, Rick, Mitchell, Sara, Nacmias, Benedetta, Neason, Mollie, Nicholas, Jennifer, Öijerstedt, Linn, Olives, Jaume, Padovani, Alessandro, Panman, Jessica, Papma, Janne, Tagliavini, Fabrizio, Pievani, Michela, Pijnenburg, Yolande, Premi, Enrico, Prioni, Sara, Prix, Catharina, Rademakers, Rosa, Redaelli, Veronica, Rogaeva, Ekaterina, Rosa-Neto, Pedro, Rossi, Giacomina
Publikováno v:
Neurobiology of Aging, Vol. 77 (2019) pp. 169-177
Neurobiology of aging 77, 169-177 (2019). doi:10.1016/j.neurobiolaging.2018.12.009
Neurobiology of aging 77, 169-177 (2019). doi:10.1016/j.neurobiolaging.2018.12.009
© 2019 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)
The presymptomatic phase of neurodegenerative diseases are characterized by structural brain cha
The presymptomatic phase of neurodegenerative diseases are characterized by structural brain cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4dfd461e97ef0b5558f4c216fb52fd5
https://hdl.handle.net/11572/355864
https://hdl.handle.net/11572/355864
Autor:
Bradley T. Hyman, Naomi Klickstein, Marc Aurel Busche, George A. Carlson, Tarun V. Kamath, Julia Schiantarelli, Israel Nelken, Susanne Wegmann, Simon Dujardin, Caitlin Commins
Publikováno v:
Nature reviews / Neuroscience 22(1), 57-64 (2018). doi:10.1038/s41593-018-0289-8
The coexistence of amyloid-β (Aβ) plaques and tau neurofibrillary tangles in the neocortex is linked to neural system failure and cognitive decline in Alzheimer’s disease. However, the underlying neuronal mechanisms are unknown. By employing in v
Autor:
Anton Ivanov, Vu Thao Quyen Le-Schulte, Christophe Bernard, Fabio Morellini, Ronny Eichler, Axel Neu, Stephan Lawrence Marguet, Igor Jakovcevski, Ileana L. Hanganu-Opatz, Dirk Isbrandt, Andrea Merseburg
Publikováno v:
Nature medicine 21(12), 1436-1444 (2015). doi:10.1038/nm.3987
The nervous system is vulnerable to perturbations during specific developmental periods. Insults during such susceptible time windows can have long-term consequences, including the development of neurological diseases such as epilepsy. Here we report
Autor:
Benno Gesierich, Marco Duering, Ruthger Righart, Martin Dichgans, Vera Zietemann, Frank A. Wollenweber
Publikováno v:
Neurology 84(16), 1685-1692 (2015). doi:10.1212/WNL.0000000000001502
To study remote effects distant from acute ischemic infarcts by measuring longitudinal changes of cortical thickness in connected brain regions as well as changes in microstructural integrity in connecting fiber tracts.Thirty-two patients (mean age 7
Publikováno v:
The lancet / Psychiatry 4(10), 768-774 (2017). doi:10.1016/S2215-0366(17)30330-9
Summary Background In anti-NMDA receptor (NMDAR) encephalitis, antibody-mediated dysfunction of NMDARs causes severe neuropsychiatric symptoms, including psychosis, memory deficits, and movement disorders. However, it remains elusive how antibody-med