Výsledky vyhledávání - "pathology [Breast Neoplasms]"

Systematic evaluation of cell-SELEX enriched aptamers binding to breast cancer cells

Autor: Silvana K. Haßel, Seyed Mohammad Taghdisi, Anna Jonczyk, H. James Stunden, Günter Mayer, Joachim L. Schultze, Marc Beyer, Laia Civit, Eicke Latz, Michael Blank, Carsten Gröber

Publikováno v: Civit Pitarch, L, Taghdisi, S M, Jonczyk, A, Hassel, S K, Gröber, C, Blank, M, Stunden, J, Beyer, M, Schultze, J, Latz, E & Mayer, G 2018, ' Systematic evaluation of cell-SELEX enriched aptamers binding to breast cancer cells ', Biochimie, vol. 145, pp. 53-62 . https://doi.org/10.1016/j.biochi.2017.10.007
Biochimie 145, 53-62 (2018). doi:10.1016/j.biochi.2017.10.007

The sensitive and specific detection of pathogenic cells is essential in clinical diagnostics. To achieve this, molecular tools are required that unequivocally recognise appropriate cell surface molecules, such as biomarkers that come along with dise

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c5b5cc0c510193c317291b71c3107a
https://doi.org/10.1016/j.biochi.2017.10.007

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Cytosolic Hsp90α and its mitochondrial isoform Trap1 are differentially required in a breast cancer model

Autor: Thomas Floss, Evangelia Vartholomaiou, Didier Picard, Marta Madon-Simon, Guillaume Muhlebach, Wolfgang Wurst, Stéphane Hagmann

Publikováno v: Oncotarget
Oncotarget, Vol. 8 (2017) pp. 17428-17442
OncoTarget 8(11), 17428-17442 (2017). doi:10.18632/oncotarget.15659
Oncotarget 8, 17428-17442 (2017)

// Evangelia Vartholomaiou 1,* , Marta Madon-Simon 1,* , Stephane Hagmann 1 , Guillaume Muhlebach 1 , Wolfgang Wurst 2,3,4,5 , Thomas Floss 2 and Didier Picard 1 1 Departement de Biologie Cellulaire, Universite de Geneve, Sciences III, Geneve, Switze

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e50f246025a20bb235fb56c0c865d6d8
http://europepmc.org/articles/PMC5392260

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Transcriptional Signature Derived from Murine Tumor-Associated Macrophages Correlates with Poor Outcome in Breast Cancer Patients

Autor: Theodore S. Kapellos, Cheei-Sing Hau, Thomas Ulas, Lea Seep, Kathrin Klee, Sander Tuit, Karin E. de Visser, Joachim L. Schultze, Marie Oestreich, Camilla Salvagno

Publikováno v: Cell reports 29(5), 1221-1235.e5 (2019). doi:10.1016/j.celrep.2019.09.067
Cell Reports, Vol 29, Iss 5, Pp 1221-1235.e5 (2019)
Cell Reports

Summary Tumor-associated macrophages (TAMs) are frequently the most abundant immune cells in cancers and are associated with poor survival. Here, we generated TAM molecular signatures from K14cre;Cdh1flox/flox;Trp53flox/flox (KEP) and MMTV-NeuT (NeuT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::904352c6d4f6141b90f99b49221c7e34

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Global and focal brain volume in long-term breast cancer survivors exposed to adjuvant chemotherapy

Autor: Henri A. Vrooman, Willem Boogerd, Wiro J. Niessen, Sanne B. Schagen, Caroline Seynaeve, Vincent Koppelmans, Fedde van der Lijn, Aad van der Lugt, Monique M.B. Breteler, Michiel B. de Ruiter

Publikováno v: Breast cancer research and treatment, 132(3)2012
Breast Cancer Research and Treatment, 132(3), 1099-1106. Springer New York
Breast cancer research and treatment, 132(3), 1099-1106. Springer New York
Breast cancer research and treatment 132(3), 1099-1106 (2011). doi:10.1007/s10549-011-1888-1

A limited number of studies have associated adjuvant chemotherapy with structural brain changes. These studies had small sample sizes and were conducted shortly after cessation of chemotherapy. Results of these studies indicate local gray matter volu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e16bf1be88b3d56e4ff2c94eff30ef81
http://resolver.tudelft.nl/uuid:035a1f2c-191f-4f1f-8a60-6be3ece14a7a

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Imaging breast cancer chemotherapy response with light. Commentary on Soliman et al., p. 2605

Autor: Tromberg, Bruce J, Cerussi, Albert E

Publikováno v: Tromberg, Bruce J; & Cerussi, Albert E. (2010). Imaging breast cancer chemotherapy response with light. Commentary on Soliman et al., p. 2605.. Clinical cancer research : an official journal of the American Association for Cancer Research, 16(9), 2486-2488. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/12q1023t

Diffuse optical spectroscopy (DOS), which is used to image tumor metabolic response to neoadjuvant chemotherapy (NAC), shows large changes in tumor functional parameters with significant reductions in oxy- and deoxyhemoglobin for responders versus no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::dfecddcb3bf60d42bd21e2377c90cf1c
http://www.escholarship.org/uc/item/12q1023t

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Diffuse optical spectroscopy measurements of healing in breast tissue after core biopsy: case study

Autor: Wendy Tanamai, Bruce J. Tromberg, David Hsiang, Cynthia Chen, Albert E. Cerussi, John Butler, Sara Siavoshi

Publikováno v: Tanamai, Wendy; Chen, Cynthia; Siavoshi, Sara; Cerussi, Albert; Hsiang, David; Butler, John; et al.(2009). Diffuse optical spectroscopy measurements of healing in breast tissue after core biopsy: case study.. Journal of biomedical optics, 14(1), 014024-0140014024. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/9xn5h4hj

Diffuse optical spectroscopy (DOS) has been used to monitor and predict the effects of neoadjuvant (i.e., presurgical) chemotherapy in breast cancer patients in several pilot studies. Because patients with suspected breast cancers undergo biopsy prio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f71809964f4e00977810a009c8e6ad1
http://www.escholarship.org/uc/item/9xn5h4hj

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The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer

Autor: Henrik Clausen, Martin Dalziel, Thomas Noll, Joyce Taylor-Papadimitriou, Steven Gschmeissner, Robert Sewell, Malin Bäckström, Joy Burchell, Hasse Karlsson, Gunnar C. Hansson, Jochem Gätgens

Publikováno v: University of Copenhagen
The journal of biological chemistry 281, 3586-3594 (2006). doi:10.1074/jbc.M511826200

The functional properties of glycoproteins are strongly influenced by their profile of glycosylation, and changes in this profile are seen in malignancy. In mucin-type O-linked glycosylation these changes can result in the production of mucins such a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::646e331df987a1ab52bb669356293480
https://pubmed.ncbi.nlm.nih.gov/16319059

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Imaging in breast cancer: diffuse optics in breast cancer: detecting tumors in pre-menopausal women and monitoring neoadjuvant chemotherapy

Autor: Amanda Durkin, Bruce J. Tromberg, Albert E. Cerussi, Natasha Shah, John Butler, Montana Compton, David Hsiang, Rita S. Mehta

Publikováno v: Tromberg, Bruce J; Cerussi, Albert; Shah, Natasha; Compton, Montana; Durkin, Amanda; Hsiang, David; et al.(2005). Imaging in breast cancer: diffuse optics in breast cancer: detecting tumors in pre-menopausal women and monitoring neoadjuvant chemotherapy.. Breast cancer research : BCR, 7(6), 279-285. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/6xb390wn
Breast Cancer Research

Diffuse optical spectroscopy (DOS) and diffuse optical imaging (DOI) are non-invasive diagnostic techniques that employ near-infrared (NIR) light to quantitatively characterize the optical properties of centimeter-thick, multiple-scattering tissues.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd34a22e313aaa925b928eec48804aa
http://www.escholarship.org/uc/item/6xb390wn

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