Zobrazeno 1 - 10
of 128
pro vyhledávání: '"parviz Abdolmaleki"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Ferroptosis is a regulated form of cell death characterized by iron-dependent lipid peroxidation of polyunsaturated fatty acids (PUFAs). Despite its significance, the precise molecular mechanisms underlying ferroptosis remain elusive, particularly co
Externí odkaz:
https://doaj.org/article/c75a378c2f0242b39606f491e551d413
Autor:
Jaber Zafari, Nima Rastegar-Pouyani, Fatemeh Javani Jouni, Nabaa Najjar, Seyedeh Zohreh Azarshin, Emad Jafarzadeh, Parviz Abdolmaleki, Farshad Hoseini Shirazi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Cisplatin is a chemotherapy drug widely used in cancer treatment. Alongside its clinical benefits, however, it may inflict intolerable toxicity and other adverse effects on healthy tissues. Due to the limitation of administering a high dose
Externí odkaz:
https://doaj.org/article/42a2f23fde0e43ce9f3dd35db8585419
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Superparamagnetic nanoparticles (SPMNPs) have attracted considerable attention in biomedicine, particularly magnetic hyperthermia for cancer treatment. However, the development of efficient and eco-friendly methods for synthesizing SPMNPs remains a c
Externí odkaz:
https://doaj.org/article/ad3935c0c35a48d4875a4b7377c5a696
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Breast cancer is one of the leading causes of cancer deaths in women worldwide. Magnetic fields have shown anti-tumor effects in vitro and in vivo as a non-invasive therapy method that can affect cellular metabolism remotely. Doxorubicin (DO
Externí odkaz:
https://doaj.org/article/8b4c11af16974b33baeebaeea004cd92
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundDrug resistance in cancer cells is a major concern in chemotherapy. Cisplatin (CIS) is one of the most effective chemotherapeutics for ovarian cancer. Here, we investigated an experimental approach to increase CIS cytotoxicity and overcome
Externí odkaz:
https://doaj.org/article/a739a742e4a14fa78a39b67d17d0bd9e
Autor:
Narjes Mohammadi Ballakuti, Faezeh Ghanati, Hassan Zare-Maivan, Mozhgan Alipour, Mahtab Moghaddam, Parviz Abdolmaleki
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Taxol (Paclitaxel) and its derivative taxanes are widely used in chemotherapy and treatment of different types of cancer. Although the extracted taxanes from Taxus sp. are currently used in semi-synthetic production of Taxol, providing alter
Externí odkaz:
https://doaj.org/article/0c9e69beac414cbf98025206bad0573a
Publikováno v:
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, Vol 29, Iss 6, Pp 20-27 (2021)
Introduction: Cancer is the leading cause of death in most countries. There are several methods used to treat cancer. Doxorubicin is one of the most important chemotherapy drugs that has several side effects, such as infertility, hyperuricemia, neuro
Externí odkaz:
https://doaj.org/article/b680da67bbb64b199dfb44da25464f4d
Autor:
Mozhgan Alipour, Mahsa Motavaf, Parviz Abdolmaleki, Alireza Zali, Farzad Ashrafi, Saeid Safari, Behnam Hajipour-Verdom
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder whose early diagnosis leads to a chance for successful treatment and decreases the side effects. Hyperphosphorylation of tau proteins is a pathological hallmark of AD that causes
Externí odkaz:
https://doaj.org/article/68c13b145d5040f498ac6f82d36ec148
Autor:
Yaser Shabanpour, Sharareh Sajjadi, Esmaeil Behmard, Parviz Abdolmaleki, Amir Homayoun Keihan
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The human immunodeficiency virus type 1 protease (HIV-1 PR) is an important enzyme in the life cycle of the HIV virus. It cleaves inactive pre-proteins of the virus and changes them into active proteins. Darunavir (DRV) suppresses the wild-type HIV-1
Externí odkaz:
https://doaj.org/article/8d0caeaa315b4fa285c3fdece790853a
Autor:
Esmaeil Behmard, Hussein T Abdulabbas, Saade Abdalkareem Jasim, Sohrab Najafipour, Abdolmajid Ghasemian, Akbar Farjadfar, Ebrahim Barzegari, Amin Kouhpayeh, Parviz Abdolmaleki
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0272582 (2022)
Hepatitis C virus (HCV) infects the liver and causes chronic infection. Several mutations in the viral genome have been associated with drug resistance development. Currently, there is no approved vaccine against the HCV. The employment of computatio
Externí odkaz:
https://doaj.org/article/291ac45854564b36a44b037e1529ec5e