Uncertainty quantification of parenchymal tracer distribution using random diffusion and convective velocity fields

Autor: Matteo Croci, Vegard Vinje, Marie E. Rognes

Publikováno v: Fluids and Barriers of the CNS, Vol 16, Iss 1, Pp 1-21 (2019)

Abstract Background Influx and clearance of substances in the brain parenchyma occur by a combination of diffusion and convection, but the relative importance of these mechanisms is unclear. Accurate modeling of tracer distributions in the brain reli

Externí odkaz: https://doaj.org/article/30ec40f561804f098a804866d53692f0

Changing the Currently Held Concept of Cerebrospinal Fluid Dynamics Based on Shared Findings of Cerebrospinal Fluid Motion in the Cranial Cavity Using Various Types of Magnetic Resonance Imaging Techniques

Autor: Mitsunori Matsumae, Satoshi Yatsushiro, Kagayaki Kuroda, Naokazu Hayashi, Akihiro Hirayama, Takatoshi Sorimachi, Hideki Atsumi, Ken Takizawa

Publikováno v: Neurologia medico-chirurgica

The "cerebrospinal fluid (CSF) circulation theory" of CSF flowing unidirectionally and circulating through the ventricles and subarachnoid space in a downward or upward fashion has been widely recognized. In this review, observations of CSF motion us

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb221579e9a17c75564a0d6b4f29138
https://doi.org/10.2176/nmc.ra.2018-0272

Rapid lymphatic efflux limits cerebrospinal fluid flow to the brain

Autor: Arno Bücker, Qiaoli Ma, Klaus Fassbender, Yann Decker, Miriam Ries, Michael Detmar, Steven T. Proulx, Chantal Riner, Andreas Müller

Publikováno v: Acta Neuropathologica, 137 (1)
Acta Neuropathologica
Ma, Qiaoli; Ries, Miriam; Decker, Yann; Müller, Andreas; Riner, Chantal; Bücker, Arno; Fassbender, Klaus; Detmar, Michael; Proulx, Steven T. (2019). Rapid lymphatic efflux limits cerebrospinal fluid flow to the brain. Acta neuropathologica, 137(1), pp. 151-165. Springer-Verlag 10.1007/s00401-018-1916-x

The relationships between cerebrospinal fluid (CSF) and brain interstitial fluid are still being elucidated. It has been proposed that CSF within the subarachnoid space will enter paravascular spaces along arteries to flush through the parenchyma of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::304aa198efc9a027922241159c9ccab0
https://hdl.handle.net/20.500.11850/318439

Voluntary Exercise Promotes Glymphatic Clearance of Amyloid Beta and Reduces the Activation of Astrocytes and Microglia in Aged Mice

Autor: Feng-ying Liang, Jinsheng Zeng, Yue Lan, Guang-yan Dai, Qun Zhang, Xiao-fei He, Dong-xu Liu, Zhong Pei, Guang-qing Xu

Publikováno v: Frontiers in Molecular Neuroscience, Vol 10 (2017)
Frontiers in Molecular Neuroscience

Age is characterized by chronic inflammation, leading to synaptic dysfunction and dementia because the clearance of protein waste is reduced. The clearance of proteins depends partly on the permeation of the blood–brain barrier (BBB) or on the exch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f3fcbabe364898f18c5114cdb352991
https://doi.org/10.3389/fnmol.2017.00144

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.