Zobrazeno 1 - 10
of 93
pro vyhledávání: '"parasite genomics"'
Autor:
Vincenzo A. Ellis, Victor Kalbskopf, Arif Ciloglu, Mélanie Duc, Xi Huang, Abdullah Inci, Staffan Bensch, Olof Hellgren, Vaidas Palinauskas
Publikováno v:
Parasites & Vectors, Vol 15, Iss 1, Pp 1-12 (2022)
Abstract Background Sequencing parasite genomes in the presence of host DNA is challenging. Sequence capture can overcome this problem by using RNA probes that hybridize with the parasite DNA and then are removed from solution, thus isolating the par
Externí odkaz:
https://doaj.org/article/a1de9cad74d6469480d6e10e18f91f04
Autor:
Amy Wesolowski, Aimee R Taylor, Hsiao-Han Chang, Robert Verity, Sofonias Tessema, Jeffrey A Bailey, T Alex Perkins, Daniel E Neafsey, Bryan Greenhouse, Caroline O Buckee
Publikováno v:
BMC Medicine, Vol 16, Iss 1, Pp 1-8 (2018)
Abstract Background Recent global progress in scaling up malaria control interventions has revived the goal of complete elimination in many countries. Decreasing transmission intensity generally leads to increasingly patchy spatial patterns of malari
Externí odkaz:
https://doaj.org/article/448d92a96d6d40a2b71b8121cb25e039
Autor:
Sofonias Tessema, Amy Wesolowski, Anna Chen, Maxwell Murphy, Jordan Wilheim, Anna-Rosa Mupiri, Nick W Ruktanonchai, Victor A Alegana, Andrew J Tatem, Munyaradzi Tambo, Bradley Didier, Justin M Cohen, Adam Bennett, Hugh JW Sturrock, Roland Gosling, Michelle S Hsiang, David L Smith, Davis R Mumbengegwi, Jennifer L Smith, Bryan Greenhouse
Publikováno v:
eLife, Vol 8 (2019)
Local and cross-border importation remain major challenges to malaria elimination and are difficult to measure using traditional surveillance data. To address this challenge, we systematically collected parasite genetic data and travel history from t
Externí odkaz:
https://doaj.org/article/dd0b160873ca457bb3a195804bf4d245
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Previous studies have shown that P. falciparum parasites in South America have undergone population bottlenecks resulting in clonal lineages that are differentially distributed and that have been responsible for several outbreaks different endemic re
Autor:
Narcis B. Kabatereine, James Cotton, Fiona Allan, Matthew Berriman, Alan Tracey, Nancy Holroyd, Joanne P. Webster, Jennifer D. Noonan, Poppy H. L. Lamberton, Duncan Berger, Moses Adriko, Thomas Crellen, Edridah M. Tukahebwa
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications
Control and elimination of the parasitic disease schistosomiasis relies on mass administration of praziquantel. Whilst these programmes reduce infection prevalence and intensity, their impact on parasite transmission and evolution is poorly understoo
Autor:
Villena, Fredy E., Sanchez, Juan F., Nolasco, Oscar, Braga, Greys, Ricopa, Leonila, Barazorda, Keare, Salas, Carola J., Lucas, Carmen, Lizewski, Stephen E., Joya, Christie A., Gamboa, Dionicia, Delgado Ratto, Christopher, Valdivia, Hugo O.
Publikováno v:
Scientific reports
Malaria is a major health problem in Peru despite substantial progress achieved by the ongoing malaria elimination program. This study explored the population genetics of 63 Plasmodium falciparum and 170 P. vivax cases collected in the Peruvian Amazo
Autor:
Courage Kakaney, Jones A. Amponsah, Festus K. Acquah, Kim C. Williamson, Elizabeth Cudjoe, Anwar E. Ahmed, Linda E. Amoah, James S. McCarthy, Michelle C. Barbeau, Ruth Ayanful-Torgby, Benjamin Abuaku, Evans K. Obboh, Surendra K Prajapati, Zuleima Pava
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
Malaria is spread by the transmission of sexual stage parasites, called gametocytes. However, with Plasmodium falciparum, gametocytes can only be detected in peripheral blood when they are mature and transmissible to a mosquito, which complicates con
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Philasterides dicentrarchi is a marine benthic microaerophilic scuticociliate and an opportunistic endoparasite that can infect and cause high mortalities in cultured turbot (Scophthalmus maximus). In addition to a cytochrome pathway (CP), the ciliat
Autor:
Jianzhu Chen, Regina Hoo, Peter R. Preiser, Radoslaw Igor Omelianczyk, Han Ping Loh, Sebastian Baumgarten, Laurent Rénia, Marvin Chew
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-11 (2020)
Communications Biology
Communications Biology
The genomes of Plasmodium spp. encode a number of different multigene families that are thought to play a critical role for survival. However, with the exception of the P. falciparum var genes, very little is known about the biological roles of any o
Autor:
Sabine Anne-Kristin Fraschka, George K. Christophides, Kathrin Witmer, Dina Vlachou, Richárd Bártfai
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-19 (2020)
Scientific Reports, 10, 1, pp. 1-19
Scientific Reports, 10, 1-19
Scientific Reports
Scientific Reports, 10, 1, pp. 1-19
Scientific Reports, 10, 1-19
Scientific Reports
The malaria parasite replicates asexually in the red blood cells of its vertebrate host employing epigenetic mechanisms to regulate gene expression in response to changes in its environment. We used chromatin immunoprecipitation followed by sequencin