Drug repurposing to tackle parainfluenza 3 based on multi-similarities and network proximity analysis

Autor: Xinyue Chen, Bo Zhou, Xinyi Jiang, Huayu Zhong, Aijing You, Taiyan Zou, Chengcheng Zhou, Xiaoxiao Liu, Yonghong Zhang

Publikováno v: Frontiers in Pharmacology, Vol 15 (2024)

Given that there is currently no clinically approved drug or vaccine for parainfluenza 3 (PIV3), we applied a drug repurposing method based on disease similarity and chemical similarity to screen 2,585 clinically approved chemical drugs using PIV3 po

Externí odkaz: https://doaj.org/article/3ca5901f5e0943c3a93ca037f4db20ea

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Controlling a human parainfluenza virus-3 outbreak in a haematology ward in a tertiary hospital

Autor: Iglόi, Z., van Loo, I. H. M., Demandt, A. M. P., Franssen, K., Jonges, M., van Gelder, M., Erkens-Hulshof, S., van Alphen, L. B.

Publikováno v: Iglόi, Z, van Loo, I H M, Demandt, A M P, Franssen, K, Jonges, M, van Gelder, M, Erkens-Hulshof, S & van Alphen, L B 2022, ' Controlling a human parainfluenza virus-3 outbreak in a haematology ward in a tertiary hospital : the importance of screening strategy and molecular diagnostics in relation to clinical symptoms ', Journal of Hospital Infection, vol. 126, pp. 56-63 . https://doi.org/10.1016/j.jhin.2022.03.017
Journal of Hospital Infection, 126, 56-63. W.B. Saunders Ltd

Background: The human parainfluenza virus 3 (HPIV-3) outbreak at the haemato-oncology ward of the Maastricht University Medical Centre in the summer of 2016. Aim: To describe an effective strategy to control the largest reported HPIV-3 outbreak at an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9031c73e1f4fe5c1519308451b30cff9
https://doi.org/10.1016/j.jhin.2022.03.017

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Pathological study and detection of Bovine parainfluenza 3 virus in pneumonic sheep lungs using direct immunofluorescence antibody technique

Autor: Khireddine Ghougal, Bakir Mamache, Omar Bennoune, Sameh Baghezza

Publikováno v: Comparative Clinical Pathology

Bovine parainfluenza 3 virus is a common virus that causes respiratory tract infection in cattle, sheep, and goats worldwide. The objective of this study is to identify macroscopic and histopathological lung lesions in slaughtered sheep during the pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::befa734a1cc00240b299900afc744ad3
https://doi.org/10.1007/s00580-021-03211-6