Výsledky vyhledávání - "paradoxical growth"

Akademický článek

Adaptation of the emerging pathogenic yeast Candida auris to high caspofungin concentrations correlates with cell wall changes

Autor: Violeta Lara-Aguilar, Cristina Rueda, Irene García-Barbazán, Sarai Varona, Sara Monzón, Pilar Jiménez, Isabel Cuesta, Ángel Zaballos, Óscar Zaragoza

Publikováno v: Virulence, Vol 12, Iss 1, Pp 1400-1417 (2021)

Candida auris has emerged as a fungal pathogen that causes nosocomial outbreaks worldwide. Diseases caused by this fungus are of concern, due to its reduced susceptibility to several antifungals. C. auris exhibits paradoxical growth (PG; defined as g

Externí odkaz: https://doaj.org/article/b9fd96d77fda452abf282dce64e3cccc

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Akademický článek

Signaling Pathways Governing the Caspofungin Paradoxical Effect in Aspergillus fumigatus

Autor: Nicolas Papon, Florent Morio, Dominique Sanglard

Publikováno v: mBio, Vol 11, Iss 4 (2020)

ABSTRACT Aspergillus fumigatus is responsible for a wide range of diseases affecting several million people worldwide. Currently, a few families of antifungals are available to fight aspergillosis, and we are facing a worrisome increase in resistance

Externí odkaz: https://doaj.org/article/b6f21d2831244aad895e39a2ebededf9

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Akademický článek

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Adaptation of the emerging pathogenic yeast Candida auris to high caspofungin concentrations correlates with cell wall changes

Autor: Ángel Zaballos, Violeta Lara-Aguilar, Oscar Zaragoza, Sara Monzón, Cristina Rueda, Sarai Varona, Irene García-Barbazán, Pilar Jiménez, Isabel Cuesta

Publikováno v: Virulence
article-version (VoR) Version of Record
Virulence, Vol 12, Iss 1, Pp 1400-1417 (2021)
Repisalud
Instituto de Salud Carlos III (ISCIII)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b5d3e27d940497cf4a8d55e9cb091f
http://europepmc.org/articles/PMC8244764

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Akademický článek

Relative Frequency of Paradoxical Growth and Trailing Effect with Caspofungin, Micafungin, Anidulafungin, and the Novel Echinocandin Rezafungin against Candida Species

Autor: Zoltán Tóth, Lajos Forgács, Tamás Kardos, Renátó Kovács, Jeffrey B. Locke, Gábor Kardos, Fruzsina Nagy, Andrew M. Borman, Awid Adnan, László Majoros

Publikováno v: Journal of Fungi, Vol 6, Iss 3, p 136 (2020)

Rezafungin is a next-generation echinocandin that has favorable pharmacokinetic properties. We compared the occurrence of paradoxical growth (PG) and trailing effect (TE) characteristics to echinocadins with rezafungin, caspofungin, micafungin and an

Externí odkaz: https://doaj.org/article/a23d6cbe580347f09bb0724220ec9922

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Akademický článek

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Akademický článek

Antifungal Effect of Novel 2-bromo-2-chloro-2-(4-chlorophenylsulfonyl)-1-phenylethanone against Candida strains

Autor: Monika Staniszewska, Małgorzata Bondaryk, Magdalena Wieczorek, Eine Estrada-Mata, Hector Manuel Mora Montes, Zbigniew Ochal

Publikováno v: Frontiers in Microbiology, Vol 7 (2016)

We investigated the antifungal activity of novel a 2-bromo-2-chloro-2-(4-chlorophenylsulfonyl)-1-phenylethanone (compound 4). The synthesis of compound 4 was commenced from sodium 4-chlorobenzene sulfinate and the final product was obtained by treatm

Externí odkaz: https://doaj.org/article/1a7110aeff19468cbb2bb57cdbecdffa

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Paradoxical Increase in Body Mass Induced by Beta-Guanidinopropionic Acid in Juvenile Spontaneously Hypertensive Rats

Autor: L M. Brewster

Publikováno v: Cureus

Background The adenosine triphosphate (ATP) regenerating enzyme creatine kinase (CK) is intimately involved in blood pressure generation. Consequently, the creatine transporter and CK inhibitor beta-guanidinopropionic acid (GPA) successfully reduced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ccc833b180ea83ed03bee4f1faa2ad0
https://doi.org/10.7759/cureus.19394

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Akademický článek

Recent Insights into the Paradoxical Effect of Echinocandins

Autor: Johannes Wagener, Veronika Loiko

Publikováno v: Journal of Fungi, Vol 4, Iss 1, p 5 (2017)

Echinocandin antifungals represent one of the most important drug classes for the treatment of invasive fungal infections. The mode of action of the echinocandins relies on inhibition of the β-1,3-glucan synthase, an enzyme essentially required for

Externí odkaz: https://doaj.org/article/04ff65c4531548568fd4cbbe241d1a8c

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Akademický článek

Role of Virulence Determinants in Candida albicans’ Resistance to Novel 2-bromo-2-chloro-2-(4-chlorophenylsulfonyl)-1-phenylethanone

Autor: Monika Staniszewska, Małgorzata Bondaryk, Zbigniew Ochal

Publikováno v: Journal of Fungi, Vol 3, Iss 3, p 32 (2017)

We investigated the role of KEX2, SAP4-6, EFG1, and CPH1 in the virulence of Candida under a novel compound 2-bromo-2-chloro-2-(4-chlorophenylsulfonyl)-1-phenylethanone (Compound 4). We examined whether the exposure of C. albicans cells to Compound 4

Externí odkaz: https://doaj.org/article/d163f5b8ebcb4f8aa4b38d1f6d723975

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