Zobrazeno 1 - 10
of 736
pro vyhledávání: '"paracrine signaling"'
Autor:
Divya Sridharan, Julie A. Dougherty, Uzair Ahmed, Shridhar K. Sanghvi, Syed Baseeruddin Alvi, Ki Ho Park, Helena Islam, Sue E. Knoblaugh, Harpreet Singh, Elizabeth D. Kirby, Mahmood Khan
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Background Human induced pluripotent stem cells (hiPSCs) and their differentiated cell types have a great potential for tissue repair and regeneration. While the primary focus of using hiPSCs has historically been to regenerate damaged tissu
Externí odkaz:
https://doaj.org/article/3817c12ff63f4441b96167eaf8169674
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionMacrophages play a key role in most of the inflammatory diseases such as Rheumatoid Arthritis (RA), but the mechanism underlying their pathogenesis is still under study. Among stem cells, human dental pulp stem cells (hDPSCs) have attract
Externí odkaz:
https://doaj.org/article/214f3247485d49d7b17b398459750482
Autor:
Tianchu Wang, Ryan T. Wagner, Ryan A. Hlady, Xiaoyu Pan, Xia Zhao, Sungho Kim, Liguo Wang, Jeong‐Heon Lee, Huijun Luo, Erik P. Castle, Douglas F. Lake, Thai H. Ho, Keith D. Robertson
Publikováno v:
Molecular Oncology, Vol 18, Iss 1, Pp 44-61 (2024)
Histone‐lysine N‐methyltransferase SETD2 (SETD2), the sole histone methyltransferase that catalyzes trimethylation of lysine 36 on histone H3 (H3K36me3), is often mutated in clear cell renal cell carcinoma (ccRCC). SETD2 mutation and/or loss of H
Externí odkaz:
https://doaj.org/article/94fc00dd4ad84cafa77273b4de5bc7d6
Autor:
Jordan Carroll, Jessie Chen, Rahul Mittal, Joana R. N. Lemos, Mannat Mittal, Shreya Juneja, Amro Assayed, Khemraj Hirani
Publikováno v:
Cells, Vol 13, Iss 22, p 1914 (2024)
Alpha cells in the pancreas, traditionally known for their role in secreting glucagon to regulate blood glucose levels, are gaining recognition for their involvement in the pathophysiology of type 1 diabetes (T1D). In T1D, autoimmune destruction of b
Externí odkaz:
https://doaj.org/article/540fc38ccca4484baae854cea78260eb
Autor:
Aysegul Atasoy-Zeybek, Michael J. Coenen, Gresin P. Hawse, Delphine Logeart-Avramoglou, Christopher H. Evans, Rodolfo E. De La Vega
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 350-363 (2023)
Bone morphogenetic protein-2 (BMP-2) is an osteogenic protein used clinically to enhance bone healing. However, it must be applied in very high doses, causing adverse side effects and increasing costs while providing only incremental benefit. Preclin
Externí odkaz:
https://doaj.org/article/a6616c8594034237bd2d18ec1d533163
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 271, Iss , Pp 115994- (2024)
Chronic exposure to crystalline silica (CS) contributes to pulmonary fibrosis. Airway epithelium dysfunction and fibroblast activation have both been recognized as pivotal players, alongside disturbances in ferroptosis and glycolysis reprogramming. H
Externí odkaz:
https://doaj.org/article/5fc201d94be44aba96d14a8286158f0d
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The vascular endothelium is a multifunctional cellular system which directly influences blood components and cells within the vessel wall in a given tissue. Importantly, this cellular interface undergoes critical phenotypic changes in response to var
Externí odkaz:
https://doaj.org/article/ef3cca5466c24aa7ae58cdcb05c406b8
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