Zobrazeno 1 - 10
of 2 048
pro vyhledávání: '"pancreatic neuroendocrine tumors"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Pancreatic neuroendocrine neoplasms (Pan-NEN) represent a group of highly heterogeneous cancers, characterized by complex and diverse biological behavior. The objective of this study was to systematically investigate the immunological featur
Externí odkaz:
https://doaj.org/article/ab1f900df27f4760be2d01bef7360a69
Autor:
Leandra Piscopo, Emilia Zampella, Fabio Volpe, Valeria Gaudieri, Carmela Nappi, Erica Di Donna, Stefania Clemente, Antonio Varallo, Mariano Scaglione, Alberto Cuocolo, Michele Klain
Publikováno v:
Current Oncology, Vol 31, Iss 9, Pp 5617-5629 (2024)
The aim of the present study was to evaluate the safety and efficacy of radionuclide therapy with [177Lu]Lu-DOTA-TATE according to our single center experience at the University of Naples Federico II. For the present analysis, we considered 21 patien
Externí odkaz:
https://doaj.org/article/a2dee3d0e61b43c9b6b706b9d0bab36d
Autor:
Mengke Ma, Wenchao Gu, Yun Liang, Xueping Han, Meng Zhang, Midie Xu, Heli Gao, Wei Tang, Dan Huang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Postoperative liver metastasis significantly impacts the prognosis of pancreatic neuroendocrine tumor (panNET) patients after R0 resection. Combining computational pathology and deep learning radiomics can enhance the detection of
Externí odkaz:
https://doaj.org/article/33843db9e41340af9a33c6eda218aebe
Autor:
Masahiro Shimura, Hiroyuki Kato, Yukio Asano, Hidetoshi Nagata, Yuka Kondo, Satoshi Arakawa, Daisuke Koike, Takayuki Ochi, Hironobu Yasuoka, Toki Kawai, Takahiko Higashiguchi, Hiroki Tani, Yoshiki Kunimura, Kazuma Horiguchi, Yutaro Kato, Masahiro Ito, Tsunekazu Hanai, Akihiko Horiguchi
Publikováno v:
Fujita Medical Journal, Vol 10, Iss 3, Pp 69-74 (2024)
Objective: This study was performed to demonstrate the clinical application of duodenum-preserving pancreatic head resection (DPPHR) as a surgical treatment for pancreatic neuroendocrine tumors (PNETs) in terms of both curability and maintenance of p
Externí odkaz:
https://doaj.org/article/da7abb3922a44195b53226ccaf35d47b
Publikováno v:
AACE Clinical Case Reports, Vol 10, Iss 4, Pp 160-163 (2024)
Background/Objective: Hypercalcemia is a common occurrence associated with malignancy, due to a number of causes: (1) lytic bone metastases, (2) production of 1,25-dihydroxyvitamin D from lymphoma, and (3) parathyroid hormone–related peptide (PTHrP
Externí odkaz:
https://doaj.org/article/5b0c0dbf5c0d4c54a5c3561231c3193f
Publikováno v:
Cancer Reports, Vol 7, Iss 9, Pp n/a-n/a (2024)
ABSTRACT Aims Surgical resection is the primary treatment option for patients diagnosed with nonfunctional pancreatic neuroendocrine tumors (NF‐Pan‐NETs). However, the postoperative prognostic evaluation for NF‐Pan‐NET patients remains obscur
Externí odkaz:
https://doaj.org/article/b41bd739eb894ad68354cee7793e85c1
Autor:
Junfeng Xu, Xin Lou, Fei Wang, Wuhu Zhang, Xiaowu Xu, Zeng Ye, Qifeng Zhuo, Yan Wang, Desheng Jing, Guixiong Fan, Xuemin Chen, Yue Zhang, Chenjie Zhou, Jie Chen, Yi Qin, Xianjun Yu, Shunrong Ji
Publikováno v:
Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)
Abstract O6‐methylguanine DNA methyltransferase (MGMT) removes alkyl adducts from the guanine O6 position (O6‐MG) and repairs DNA damage. High MGMT expression results in poor response to temozolomide (TMZ). However, the biological importance of M
Externí odkaz:
https://doaj.org/article/b9de0dc9db3b4166a7eac67e8116e9ed
Autor:
Yu Jiang, Yi-han Dong, Shi-wei Zhao, Dong-yu Liu, Ji-yang Zhang, Xiao-ya Xu, Hao Chen, Jia-bin Jin
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Pancreatic neuroendocrine tumors (PanNETs), though uncommon, have a high likelihood of spreading to other body parts. Previously, the genetic diversity and evolutionary patterns in metastatic PanNETs were not well understood. To investigate
Externí odkaz:
https://doaj.org/article/4668c6539ddf4edfb971ffedb18752f1
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34344- (2024)
Objectives: This research aimed to retrospectively construct and authenticate ultrasomics models using endoscopic ultrasonography (EUS) images for forecasting the pathological grading of pancreatic neuroendocrine tumors (PNETs). Methods: After confir
Externí odkaz:
https://doaj.org/article/8d992e4e3460457d8a997c20800dfa9b
Autor:
Shuangyang Mo, Cheng Huang, Yingwei Wang, Huaying Zhao, Wenhong Wu, Haixing Jiang, Shanyu Qin
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
ObjectivesTo develop and validate radiomics models utilizing endoscopic ultrasonography (EUS) images to distinguish insulinomas from non-functional pancreatic neuroendocrine tumors (NF-PNETs).MethodsA total of 106 patients, comprising 61 with insulin
Externí odkaz:
https://doaj.org/article/f06af7b2ca1f4fdf8ee28cafc222110a