Reduced Insulin Sensitivity as a Marker for Acute Mountain Sickness?

Autor: Marco Maggiorini, Thomas A. Lutz, Max Gassmann, Wolfgang Langhans, Daniela Meier, Oliver Goetze, Isabelle Aeberli, Kerstin Spliethoff

Publikováno v: HIGH ALTITUDE MEDICINE & BIOLOGY

Reduced insulin sensitivity might increase the susceptibility to acute mountain sickness (AMS). The diabetogenic side effects of dexamethasone should therefore be considered for AMS treatment. To examine whether reduced insulin sensitivity is predict

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf0ab6462975c135cc70be283b68de32

Disruption of the Dopamine D2 Receptor Impairs Insulin Secretion and Causes Glucose Intolerance

Autor: David J. Hill, Marcelo Rubinstein, Edith Arany, Astrid Chamson-Reig, Ana Maria Ornstein, Michael B. Wheeler, Isabel García-Tornadú, Damasia Becu-Villalobos

Publikováno v: Paediatrics Publications
Endocrinology 2010;151(4):1441-1450
Biblioteca Digital (UBA-FCEN)
Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
instacron:UBA-FCEN

The relationship between antidopaminergic drugs and glucose has not been extensively studied, even though chronic neuroleptic treatment causes hyperinsulinemia in normal subjects or is associated with diabetes in psychiatric patients. We sought to ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14d4ffb7b0789af3b6a18291ffa9fd3d
https://doi.org/10.1210/en.2009-0996

Geniposide protects pancreatic INS-1E β cells from hIAPP-induced cell damage: potential involvement of insulin degrading-enzyme

Autor: Zhang, Yonglan, Yin, Fei, Liu, Jianhui, Wang, Yanwen

Islet amyloid deposition is increasingly seen as a pathogenic feature of type 2 diabetes mellitus (T2DM), with the deposits containing the unique amyloidogenic peptide islet amyloid polypeptide (IAPP, also known as amylin). The fibril precursors of I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1674::b0e323da910549557da9312f37e21716
https://doi.org/10.1002/cbin.10394

Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and Type 2 diabetes susceptibility

Autor: Daniel R. Witte, Brenda W.J.H. Penninx, A.G. Uitterlinden, Marian Beekman, Elisabeth M.W. Eekhoff, Louis M. Havekes, Leen M 't Hart, Jeanine J. Houwing-Duistermaat, J.M. Dekker, Gonneke Willemsen, Abbas Dehghan, Johannes A. Romijn, Robert J. Heine, N. van Leeuwen, Bruno Guigas, Nicole Vogelzangs, Torben Hansen, P.E. Slagboom, T.W. van Haeften, J. C. M. Witteman, E. van 't Riet, Hanno Pijl, Oluf Pedersen, Torsten Lauritzen, Niels Grarup, Mark H.H. Kramer, Giel Nijpels, E.J.C. de Geus, Jouke-Jan Hottenga, Albert Hofman, Annemarie M. C. Simonis-Bik, Joris Deelen, Torben Jørgensen, J. E. de Leeuw van Weenen, Michaela Diamant

Publikováno v: Diabetic Medicine, 31(8), 1001-1008. Wiley-Blackwell Publishing Ltd
Diabetic Medicine, 31(8), 1001-1008
Guigas, B, de Leeuw van Weenen, J E, van Leeuwen, N, Simonis-Bik, A M, van Haeften, T W, Nijpels, G, Houwing-Duistermaat, J J, Beekman, M, Deelen, J, Havekes, L M, Penninx, B W J H, Vogelzangs, N, van 't Riet, E, Dehghan, A, Hofman, A, Witteman, J C, Uitterlinden, A G, Grarup, N, Jørgensen, T, Witte, D, Lauritzen, T, Hansen, T, Pedersen, O, Hottenga, J, Romijn, J A, Diamant, M, Kramer, M H H, Heine, R J, Willemsen, G, Dekker, J M, Eekhoff, E M, Pijl, H, de Geus, E J, Slagboom, P E & 't Hart, L M 2014, ' Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and Type 2 diabetes susceptibility ', Diabetic medicine : a journal of the British Diabetic Association, vol. 31, no. 8, pp. 1001-8 . https://doi.org/10.1111/dme.12464
Guigas, B, de Leeuw van Weenen, J, van Leeuwen, N, Bik-Simonis, A M C, van Haeften, T W, Nijpels, G, Houwing-Duistermaat, J J, Beekman, M, Deelen, J, Havekes, L M, Penninx, B W J H, Vogelzangs, N, van 't Riet, E, Dehghan, A, Hofman, A, Witteman, J C, Uitterlinden, A G, Grarup, N, Jørgensen, T, Witte, D R, Lauritzen, T, Hansen, T, Pedersen, O, Hottenga, J J, Romijn, J A, Diamant, M, Kramer, M H H, Heine, R J, Willemsen, G, Dekker, J M, Eekhoff, E M W, Pijl, H, de Geus, E J C, Slagboom, P E & 't Hart, L M 2014, ' Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and Type 2 diabetes susceptibility ', Diabetic Medicine, vol. 31, no. 8, pp. 1001-1008 . https://doi.org/10.1111/dme.12464
Diabetic Medicine, 31(8), 1001-1008. Wiley-Blackwell
Guigas, B, van Weenen, J E D, van Leeuwen, N, Simonis-Bik, A M, van Haeften, T W, Nijpels, G, Houwing-Duistermaat, J J, Beekman, M, Deelen, J, Havekes, L M, Penninx, B, Vogelzangs, N, van 't Riet, E, Dehghan, A, Hofman, A, Witteman, J C, Uitterlinden, A G, Grarup, N, Jorgensen, T, Witte, D R, Lauritzen, T, Hansen, T, Pedersen, O, Hottenga, J, Romijn, J A, Diamant, M, Kramer, M H H, Heine, R J, Willemsen, G, Dekker, J M, Eekhoff, E M, Pijl, H, de Geus, E J, Slagboom, P E & t Hart, L M 2014, ' Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and Type 2 diabetes susceptibility ', Diabetic Medicine, vol. 31, no. 8, pp. 1001-1008 . https://doi.org/10.1111/dme.12464
Diabetic Medicine, 31(8), 1001-1008. Wiley-Blackwell Publishing
Diabetic Medicine, 8, 31, 1001-1008
Diabet Med

Aims Modulation of dopamine receptor D2 (DRD2) activity affects insulin secretion in both rodents and isolated pancreatic beta-cells. We hypothesized that single nucleotide polymorphisms in the DRD2/ANKK1 locus may affect susceptibility to Type 2 dia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e0dd7308075d7fd9f7f80224db1b2e7
https://pure.eur.nl/en/publications/31068354-33fe-48ca-9856-917bc8f380bd

Circulating Levels of MicroRNA from Children with Newly Diagnosed Type 1 Diabetes and Healthy Controls: Evidence That miR-25 Associates to Residual Beta-Cell Function and Glycaemic Control during Disease Progression:evidence that miR-25 associates to residual beta-cell function and glycaemic control during disease progression

Autor: Nielsen, Lotte B., Wang, Cheng, Sorensen, Kaspar, Bang-Berthelsen, Claus Heiner, Hansen, Lars, Andersen, Marie-Louise M., Hougaard, Philip, Juul, Anders Christian, Zhang, Chen-Yu, Pociot, Flemming, Mortensen, Henrik B.

Publikováno v: Nielsen, L B, Wang, C, Sorensen, K, Bang-Berthelsen, C H, Hansen, L, Andersen, M-L M, Hougaard, P, Juul, A C, Zhang, C-Y, Pociot, F & Mortensen, H B 2012, ' Circulating Levels of MicroRNA from Children with Newly Diagnosed Type 1 Diabetes and Healthy Controls: Evidence That miR-25 Associates to Residual Beta-Cell Function and Glycaemic Control during Disease Progression : evidence that miR-25 associates to residual beta-cell function and glycaemic control during disease progression ', Experimental Diabetes Research, vol. 2012, 896362 . https://doi.org/10.1155/2012/896362

This study aims to identify key miRNAs in circulation, which predict ongoing beta-cell destruction and regeneration in children with newly diagnosed Type 1 Diabetes (T1D). We compared expression level of sera miRNAs from new onset T1D children and ag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1202::f95e3acff7eaa8c412422a0191df7dd7
https://orbit.dtu.dk/en/publications/8d03c0d0-bbf7-4c83-9773-a02da6d4145e