Zobrazeno 1 - 10
of 1 261
pro vyhledávání: '"pan-cancer analysis"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Immunotherapy has emerged as a vital component in the contemporary landscape of cancer treatment. Recent studies have indicated that CEP55 plays an oncogenic role; however, its specific mechanisms in promoting tumor proliferation and its pot
Externí odkaz:
https://doaj.org/article/452b6cae713c46a299a151bf4057d546
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract A pan-cancer analysis summarizing the overall changes in mRNA and protein stability of ADM9, as well as its oncogenic function on immune cell line modulation and checkpoints within the tumor microenvironment (TME), is lacking, despite the fa
Externí odkaz:
https://doaj.org/article/1723da08c0fe4a2491ab4d724cce0e07
Autor:
Yang Zhou, Zhenzhen Luo, Jinfeng Guo, Lixia Wu, Xiaoli Zhou, Jun Jie Huang, Daijia Huang, Li Xiao, Qiuhua Duan, Jianhua Chang, Libao Gong, Junjie Hang
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background Sp1, a transcription factor, regulates essential cellular processes and plays important tumorigenic roles across diverse cancers. However, comprehensive pan-cancer analyses of its expression and potential immunomodulatory roles re
Externí odkaz:
https://doaj.org/article/243f3bc470d742bbaedd27025ce9266c
Autor:
Qing-xin Yu, Rui-cheng Wu, Jie Wang, Zhou-Ting Tuo, Jun Yang, Yong-ping Zhang, Jing Jin, Quan Yuan, Chun-nian Wang, De-chao Feng, Deng-xiong Li
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background Recent studies have established a correlation between ADAMTSL2 (ADAMTS-like 2) and the development of various cancers. This study aims to conduct a comprehensive pan-cancer analysis in 37 cancer types and investigate its potential
Externí odkaz:
https://doaj.org/article/8459183a11ba457390ac58c09b95a2f8
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Background GPNMB is a type I transmembrane protein, and emerging evidence supports the relationship between GPNMB and cancers. Objective Through a comprehensive pan-cancer analysis, we examined the expression levels, prognostic significance,
Externí odkaz:
https://doaj.org/article/da99621e8f904e62be8ba8f365ded02f
Autor:
Chen SL, Hu D, Chen TZ, Shen SY, Zhao CF, Wang C, Tong SY, Liu Z, Lin SH, Jin LX, He YB, Zhang ZZ
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 6743-6764 (2024)
Shi-liang Chen,1,* Dan Hu,2,* Tian-zhu Chen,3,* Si-yu Shen,4,* Chen-fei Zhao,1,* Cong Wang,1 Shi-yuan Tong,5 Zhao Liu,6 Shao-hua Lin,1 Li-xia Jin,7 Yi-bo He,1 Zhe-zhong Zhang1 1Department of Clinical Lab, The First Affiliated Hosp
Externí odkaz:
https://doaj.org/article/6434313906ed4575867b9efb2318d376
Autor:
Yi-Chao Chen, Wei-Zhong Zheng, Chun-Peng Liu, Yong-Qiang Zhao, Jun-Wei Li, Ze-Sen Du, Tian-Tian Zhai, Hao-Yu Lin, Wen-Qi Shi, Shan-Qing Cai, Feng Pan, Si-Qi Qiu
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Currently, there are no optimal biomarkers available for distinguishing patients who will respond to immune checkpoint inhibitors (ICIs) therapies. Consequently, the exploration of novel biomarkers that can predict responsiveness
Externí odkaz:
https://doaj.org/article/9ac3cb8cd59b4399be13a7a64c025086
Autor:
Chao Hu, Qingzhou Li, Lei Xiang, Yan Luo, Shengrong Li, Jun An, Xiankuo Yu, Guochen Zhang, Yuhui Chen, Yumei Wang, Dong Wang
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 234-250 (2024)
TRIB3, a pseudokinase, was previously studied within only some specific cancer types, leaving its comprehensive functions in pan-cancer contexts largely unexplored. Here, we performed an integrated analysis of TRIB3 expression, prognosis, genetic alt
Externí odkaz:
https://doaj.org/article/6eb9b5b50a194e34b47da794898e15e0
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-20 (2024)
Abstract Purpose Recent studies have increasingly linked Ephrin receptor B2 (EPHB2) to cancer progression. However, comprehensive investigations into the immunological roles and prognostic significance of EPHB2 across various cancers remain lacking.
Externí odkaz:
https://doaj.org/article/daa24ebb74294bba9106ff8718c0b22b
Autor:
Li Cao, Fang Li, Shuang Cai, Jinyuan Zhang, Chen Guo, Sadiq Ali, Jing Zhou, Xintao Jing, Xiaofei Wang, Yannan Qin, Fei Wu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Recent studies indicate that Glypican 1 (GPC-1) is aberrantly expressed and plays a key role in certain cancers, but little is known in the hepatocellular carcinoma. Raw data from TCGA, GTEx and TIMER databases were utilized to comprehensive
Externí odkaz:
https://doaj.org/article/40a0975b439a4617a3a48d808618ec89