Zobrazeno 1 - 10
of 7 050
pro vyhledávání: '"pan-cancer"'
Autor:
Yongfeng Wang, Yanzong Zhao, Guangming Zhang, Yifeng Lin, Chunling Fan, Hui Wei, Shude Chen, Ling Guan, Kan Liu, Shenhan Yu, Liangyin Fu, Jing Zhang, Yuan Yuan, Jin He, Hui Cai
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Lymphocyte activating gene-3 (LAG3) is a distinctive T cell co-receptor that is expressed on the surface of lymphocytes. It plays a special inhibitory immune checkpoint role due to its unique domain and signaling pattern. Our aim is to explo
Externí odkaz:
https://doaj.org/article/43912141bdbf44bda946214736fc3bb9
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background Malignant cells exhibit reduced period circadian regulator 3 (PER3) expression. However, the underlying mechanisms of variations in PER3 expression in cancers and the specific function of PER3 in tumor progression remain poorly un
Externí odkaz:
https://doaj.org/article/f8862a4825e446a9bf1c3ea7780f620f
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Previous studies have shown a relationship between SPECC1 and the prognosis of breast cancer, indicating a potential function for SPECC1 in the initiation and progression of cancer. However, the role played by SPECC1 in other tumors is not y
Externí odkaz:
https://doaj.org/article/bf374a35b73245968e58e25012f30149
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Background The dysregulation of fucosyltransferases (FUTs) contributes to alterations in fucosylated epitope expression, which serve as distinctive features of cancer cells. Nonetheless, a comprehensive elucidation of the prognostic biologic
Externí odkaz:
https://doaj.org/article/5f02536b94b947e3b219843c8acd724d
Autor:
Yang Zhou, Zhenzhen Luo, Jinfeng Guo, Lixia Wu, Xiaoli Zhou, Jun Jie Huang, Daijia Huang, Li Xiao, Qiuhua Duan, Jianhua Chang, Libao Gong, Junjie Hang
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background Sp1, a transcription factor, regulates essential cellular processes and plays important tumorigenic roles across diverse cancers. However, comprehensive pan-cancer analyses of its expression and potential immunomodulatory roles re
Externí odkaz:
https://doaj.org/article/243f3bc470d742bbaedd27025ce9266c
Autor:
Jie Li, Han Yang, Yixin Qi, Peng Yu, Xiahui Han, Zongliang Zhang, Kai Zhao, Xinbao Yin, Guanqun Zhu, Xuechuan Yan, Zaiqing Jiang, Xuezhen Ma, Tianzhen He, Ke Wang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Recent studies indicate that CISD3 is crucial in mitochondrial function and tumorigenesis. Using various databases, we systematically analyzed its expression, prognostic value, and immune activity. Our findings show CISD3 is mainly expressed
Externí odkaz:
https://doaj.org/article/339f4afcf556495ba514ec240ebdc9d6
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract As frontline cells, the precise recruitment of neutrophils is crucial for resolving inflammation and maintaining the homeostasis of the organism. Increasing evidence suggests the pivotal role of neutrophil chemotaxis in cancer progression an
Externí odkaz:
https://doaj.org/article/4091c30892d94779817ce71847861a89
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Background As the emergence of technologies such as sequencing and gene mapping, significant advancements have been made in understanding the landscape of tumors. However, the effective treatment of tumors continues to pose a tremendous chal
Externí odkaz:
https://doaj.org/article/8072e6a722ff47a7a5164cde8d1ebe68
Autor:
Li-Yue Sun, Yu-Ying Jiang, Xin-Xin Zeng, Ju Shen, Ke-Xin Xian, Quan-An Xu, Xian Xu, Lei Liang, Xu-Hui Zhang
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background Epstein-Barr virus (EBV) infection has been closely linked to the development of various types of cancer. EB nuclear antigen 1 binding protein 2 (EBNA1BP2) is a crucial molecule for stable isolation of EBV in latent infection. How
Externí odkaz:
https://doaj.org/article/d5f74cd79e9044948f2852e39586685f
Autor:
Qing-xin Yu, Rui-cheng Wu, Jie Wang, Zhou-Ting Tuo, Jun Yang, Yong-ping Zhang, Jing Jin, Quan Yuan, Chun-nian Wang, De-chao Feng, Deng-xiong Li
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background Recent studies have established a correlation between ADAMTSL2 (ADAMTS-like 2) and the development of various cancers. This study aims to conduct a comprehensive pan-cancer analysis in 37 cancer types and investigate its potential
Externí odkaz:
https://doaj.org/article/8459183a11ba457390ac58c09b95a2f8